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Protein Overview: CG17565-PA

General Information:
Name(s) found: CG17565-PA / FBpp0082737 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG17565 (CG17565, FBgn0038424). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12258703..12260462. It has the cytological map location 89B16. Based on sequence similarity, it is predicted to have molecular function</span>: Rab geranylgeranyltransferase activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 419 amino acids

    Gene Ontology:
    Cellular Component: Rab-protein geranylgeranyltransferase complex [ISS]
    Biological Process: NONE FOUND
    Molecular Function: Rab geranylgeranyltransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTEEELMFR NFQRLKSYIF DDEKVSTTTS REQQKTESSV EKCFDRFEQI MFTDPRLTQI  60
   61 FRLEHQYYLD AMLRRLPSNY ECLDSSRAWC VYWILQAAQL LSFNFDDQTL NHVVQFLSNC 120
  121 RSPTGGFGGG PGQYAHLAPT YAAVNSLCII GSEQAYRAID RPTLVQFLFS VRDSDGSFRL 180
  181 HVDGETDVRG AYCAISCAKL LNLPEPVIKE LFAGTGDWIA QCQTYEGGFG GAPGLEAHGG 240
  241 YTFCGIAGLA LLNEADKCDR QALLKWTLRR QMTYEGGFQG RTNKLVDGCY SFWVGATIPI 300
  301 TQATLSGVDK QMEHTLFDVE ALQEYILLCC QKQSGGLIDK PGKPQDLYHT CYTLSGVSIA 360
  361 QHSECASSPQ VLGDTINELL PTHPLFNIPP KSVAAARSHF SNSNDTEFLG KDSPSKEES

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..419] PSI-BLAST 91.154902 Protein farnesyltransferase, beta-subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein prenyltransferase activity
    		•  13.7736019666673 bayes_pls_golite062009
  • protein geranylgeranyltransferase activity
    		•  12.9757276506747 bayes_pls_golite062009
  • Rab geranylgeranyltransferase activity
    		•  12.8088011327065 bayes_pls_golite062009
  • prenyltransferase activity
    		•  11.6786310564018 bayes_pls_golite062009
  • CAAX-protein geranylgeranyltransferase activity
    		•  10.5569796788906 bayes_pls_golite062009
  • protein farnesyltransferase activity
    		•  10.5544498824038 bayes_pls_golite062009
  • binding
    		•  1.68564752993879 bayes_pls_golite062009
  • protein binding
    		•  1.45455287827127 bayes_pls_golite062009
  • transferase activity
    		•  1.0950430724883 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.854896924803117 bayes_pls_golite062009
  • catalytic activity
    		•  0.497699107100544 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle