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Protein Overview: CASP3_RAT

General Information:
Name(s) found: CASP3_RAT [Swiss-Prot]
Description(s) found:
Found 21 descriptions.
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  • Caspase-3 OS=Rattus norvegicus GN=Casp3 PE=2 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 277 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN]
    soluble fraction [IDA]
    cytoplasm [UNKNOWN][IEA]
    mitochondrion [UNKNOWN]
    cytosol [UNKNOWN][IDA][IMP]
    [NOT]nucleolus [UNKNOWN]
    plasma membrane [UNKNOWN]
    nucleoplasm [UNKNOWN]
    Biological Process: response to X-ray [IEP]
    response to wounding [UNKNOWN]
    response to amino acid stimulus [IEP]
    negative regulation of cell cycle [UNKNOWN]
    response to antibiotic [IEP]
    response to UV [UNKNOWN]
    induction of apoptosis via death domain receptors [UNKNOWN]
    induction of apoptosis by extracellular signals [UNKNOWN]
    positive regulation of neuron apoptosis [IMP]
    learning or memory [IMP]
    T cell homeostasis [UNKNOWN]
    sensory perception of sound [UNKNOWN]
    heart development [UNKNOWN]
    response to glucose stimulus [IDA]
    wound healing [IEP]
    response to hypoxia [IEP]
    negative regulation of B cell proliferation [UNKNOWN]
    induction of apoptosis [UNKNOWN][TAS]
    apoptosis [UNKNOWN][IMP]
    response to glucocorticoid stimulus [IEP]
    nuclear fragmentation during apoptosis [UNKNOWN]
    response to cobalt ion [IEP]
    response to metal ion [IEP]
    glial cell apoptosis [IEP]
    neuron apoptosis [UNKNOWN]
    response to organic substance [IEP]
    neuron differentiation [IEP]
    induction of apoptosis by oxidative stress [UNKNOWN]
    negative regulation of activated T cell proliferation [UNKNOWN]
    hippocampus development [IEP]
    response to organic cyclic substance [IEP]
    response to nicotine [IEP]
    response to hydrogen peroxide [IDA]
    response to DNA damage stimulus [UNKNOWN]
    negative regulation of cyclin-dependent protein kinase activity [UNKNOWN]
    B cell homeostasis [UNKNOWN]
    keratinocyte differentiation [UNKNOWN]
    intracellular signaling pathway [IMP]
    DNA fragmentation involved in apoptosis [UNKNOWN]
    response to drug [IEP]
    negative regulation of apoptosis [UNKNOWN]
    proteolysis [UNKNOWN][IDA]
    positive regulation of apoptosis [IMP]
    cell fate commitment [UNKNOWN]
    release of cytochrome c from mitochondria [UNKNOWN]
    response to estradiol stimulus [IEP]
    response to lipopolysaccharide [IEP]
    Molecular Function: protein binding [UNKNOWN][IPI]
    cysteine-type endopeptidase activity [UNKNOWN][IEA]
    cysteine-type peptidase activity [UNKNOWN][IDA]
    peptidase activity [UNKNOWN][IEA]
    cyclin-dependent protein kinase inhibitor activity [UNKNOWN]
    phospholipase A2 activator activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNNETSVDS KSINNFETKT IHGSKSMDSG IYLDSSYKMD YPEMGLCIII NNKNFHKSTG  60
   61 MSARNGTDVD AANLRETFMA LKYEVRNKND LTREEIMELM DSVSKEDHSK RSSFVCVILS 120
  121 HGDEGVIFGT NGPVDLKKLT SFFRGDYCRS LTGKPKLFII QACRGTELDC GIETDSGTDD 180
  181 DMACQKIPVE ADFLYAYSTA PGYYSWRNSR DGSWFIQSLC AMLKLYAHKL EFMHILTRVN 240
  241 RKVATEFESF SLDATFHAKK QIPCIVSMLT KELYFYH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle