General Information: |
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Name(s) found: |
GLP1R_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 463 amino acids |
Gene Ontology: |
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Cellular Component: |
integral to plasma membrane
[IDA]
clathrin-coated endocytic vesicle [IMP] plasma membrane [IEA] |
Biological Process: |
neuroprotection
[IDA]
insulin secretion [IMP] positive regulation of calcium ion transport via voltage-gated calcium channel activity [IMP] signal transduction [IEA] positive regulation of cell proliferation [IMP] feeding behavior [IMP] [NOT]positive regulation of glucose import [IDA] positive regulation of cell differentiation [IMP] activation of adenylate cyclase activity by G-protein signaling pathway [IMP] associative learning [IDA] positive regulation of heart contraction [IDA] positive regulation of transcription from RNA polymerase II promoter [IMP] hormone secretion [IDA] memory [IDA] positive regulation of blood pressure [IDA] elevation of cytosolic calcium ion concentration [UNKNOWN] learning or memory [IMP] neuropeptide signaling pathway [TAS] response to glucose stimulus [IMP] negative regulation of apoptosis [IDA] positive regulation of insulin secretion [IDA] release of sequestered calcium ion into cytosol [IDA] cAMP-mediated signaling [UNKNOWN][IMP] |
Molecular Function: |
peptide receptor activity
[IDA]
G-protein coupled receptor activity [TAS] peptide receptor activity, G-protein coupled [IPI] glucagon receptor activity [IEA] peptide hormone binding [IDA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MAVTPSLLRL ALLLLGAVGR AGPRPQGATV SLSETVQKWR EYRHQCQRFL TEAPLLATGL 60 61 FCNRTFDDYA CWPDGPPGSF VNVSCPWYLP WASSVLQGHV YRFCTAEGIW LHKDNSSLPW 120 121 RDLSECEESK QGERNSPEEQ LLSLYIIYTV GYALSFSALV IASAILVSFR HLHCTRNYIH 180 181 LNLFASFILR ALSVFIKDAA LKWMYSTAAQ QHQWDGLLSY QDSLGCRLVF LLMQYCVAAN 240 241 YYWLLVEGVY LYTLLAFSVF SEQRIFKLYL SIGWGVPLLF VIPWGIVKYL YEDEGCWTRN 300 301 SNMNYWLIIR LPILFAIGVN FLVFIRVICI VIAKLKANLM CKTDIKCRLA KSTLTLIPLL 360 361 GTHEVIFAFV MDEHARGTLR FVKLFTELSF TSFQGFMVAV LYCFVNNEVQ MEFRKSWERW 420 421 RLERLNIQRD SSMKPLKCPT SSVSSGATVG SSVYAATCQN SCS |
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