Protein Overview: AREG_RAT

General Information:
Name(s) found:	AREG_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8392917\|ref\|NP_058819.1\| amphiregulin preproprotein [Rattus norvegicus] [NCBI NR] gi\|49596\|emb\|CAA38967.1\| schwannoma-derived growth factor precursor [Rattus norvegicus] [NCBI NR] gi\|149033785\|gb\|EDL88581.1\| amphiregulin [Rattus norvegicus] [NCBI NR] gi\|134383\|sp\|P24338.1\|AREG_RAT RecName: Full=Amphiregulin; Short=AR; AltName: Full=Schwannoma-derived growth factor; Short=SDGF; Flags: Precursor [NCBI NR] pir\|\|S13296 Schwannoma-derived growth factor - rat [NCBI NR] Amphiregulin OS=Rattus norvegicus GN=Areg PE=1 SV=1 [Swiss-Prot] (P24338) Amphiregulin precursor (AR) (Schwannoma-derived growth factor) (SDGF) [Swiss-Prot] Ensembl_locations(Chr-bp):14-17240011 Schwannoma-derived growth factor precursor [hmr_yeast5_DM3-1_pombe.fasta] amphiregulin preproprotein; schwannoma-derived growth factor [HMR_022704-rand.fasta] amphiregulin preproprotein [Rattus norvegicus]gi\|49596\|emb\|CAA38967.1\| schwannoma-derived growth factor precursor [Rattus norvegicus]gi\|134383\|sp\|P24338\|SDGF_RAT Schwannoma-derived growth factor precursor (SDGF) (Amphiregulin) (AR)gi\|112283\|pir\|\|S13296 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Amphiregulin precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_017123) amphiregulin preproprotein [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] amphiregulin preproprotein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Amphiregulin precursor (AR) (Schwannoma-derived growth factor) (SDGF) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] amphiregulin [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] schwannoma-derived growth factor precursor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 AMPHIREGULIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Areg Amphiregulin [rat-ipi-250309-contam.fasta] Amphiregulin OS=Rattus norvegicus GN=Areg [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	243 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] extracellular space [UNKNOWN][IDA] cytoplasm [UNKNOWN][IEA] membrane [IEA] integral to membrane [IEA] intracellular [UNKNOWN][IEA] cell surface [UNKNOWN]
Biological Process:	positive regulation of phosphorylation [IDA] epithelial cell proliferation involved in mammary gland duct elongation [UNKNOWN][IEA] G-protein coupled receptor protein signaling pathway [UNKNOWN] neuron projection development [IMP] epidermal growth factor receptor signaling pathway [UNKNOWN][IDA] positive regulation of cell proliferation [IDA][IMP] response to cAMP [IEP] positive regulation of DNA replication [UNKNOWN] response to organic cyclic substance [IEP] response to hydrogen peroxide [IEP] dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis [UNKNOWN][IEA] response to peptide hormone stimulus [IEP] negative regulation of osteoblast differentiation [IDA] mammary gland branching involved in thelarche [UNKNOWN][IEA] central nervous system development [NAS] mammary gland alveolus development [UNKNOWN][IEA] response to glucocorticoid stimulus [IMP] response to estradiol stimulus [UNKNOWN][IEA] glial cell proliferation [IDA]
Molecular Function:	growth factor activity [IDA] epidermal growth factor receptor binding [IDA] cytokine activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTPSLSLAL SVLSLLVLGS GHYAAGLELN GTSSGKGEPS SGDHSAGGLV VSEVSTISEM  60
   61 PSGSELSTGD YDYSEEYDNE PQISGYIVDD SVRVEQVIKP KENKTEGEKS SEKPKRKKKG 120
  121 GKGGKGRRNR KKKKNPCAAK FQNFCIHGEC RYIENLEVVT CHCHQDYFGE RCGEKTMKTQ 180
  181 KKDDSDLSKI ALAAIIVFVS AVSVAAIGII TAVLLRKRFF REYEEAEERR RLRQENGTAH 240
  241 AIA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: AREG_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: