General Information: |
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Name(s) found: |
TGFR2_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 567 amino acids |
Gene Ontology: |
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Cellular Component: |
integral to plasma membrane
[IDA]
caveola [UNKNOWN][IMP] cytoplasm [IDA] membrane [IEA] transforming growth factor beta receptor complex [IC] external side of plasma membrane [UNKNOWN] integral to membrane [UNKNOWN][IEA] cytosol [IDA] receptor complex [UNKNOWN][IEA] plasma membrane [UNKNOWN] cell surface [IDA] |
Biological Process: |
embryonic development
[IEP]
negative regulation of cardiac muscle cell proliferation [IMP] trachea formation [UNKNOWN] response to estrogen stimulus [IEP] mammary gland morphogenesis [UNKNOWN] transforming growth factor beta receptor signaling pathway [UNKNOWN][IEA][IMP][TAS] response to glucose stimulus [IEP] wound healing [IEP] response to hypoxia [IEP][TAS] in utero embryonic development [UNKNOWN] gut development [IEP] response to cholesterol [UNKNOWN] common-partner SMAD protein phosphorylation [IDA] response to organic substance [IEP] smoothened signaling pathway [UNKNOWN] response to nutrient [IEP] trachea morphogenesis [UNKNOWN] response to organic cyclic substance [IEP] bronchus development [UNKNOWN] receptor-mediated endocytosis [IDA] bronchus morphogenesis [UNKNOWN] positive regulation of tolerance induction to self antigen [UNKNOWN] organ morphogenesis [IMP] organ regeneration [IEP] peptidyl-serine phosphorylation [UNKNOWN] peptidyl-threonine phosphorylation [UNKNOWN] positive regulation of NK T cell differentiation [UNKNOWN] lung lobe morphogenesis [UNKNOWN] negative regulation of cell proliferation [IGI][IMP] vasculogenesis [IEP] protein amino acid phosphorylation [UNKNOWN][IEA] pathway-restricted SMAD protein phosphorylation [UNKNOWN] positive regulation of B cell tolerance induction [UNKNOWN] response to mechanical stimulus [IEP] lung morphogenesis [UNKNOWN] positive regulation of smooth muscle cell proliferation [IMP] heart development [UNKNOWN] patterning of blood vessels [UNKNOWN] myeloid dendritic cell differentiation [UNKNOWN] activation of protein kinase activity [UNKNOWN] lung development [UNKNOWN][IEP] response to steroid hormone stimulus [IEP] aging [IEP] embryo implantation [IEP] regulation of cell proliferation [UNKNOWN] positive regulation of skeletal muscle tissue regeneration [IEP] gastrulation [UNKNOWN] positive regulation of T cell tolerance induction [UNKNOWN] response to drug [UNKNOWN] |
Molecular Function: |
protein homodimerization activity
[TAS]
transforming growth factor beta receptor activity [UNKNOWN] receptor activity [IEA] transforming growth factor beta receptor activity, type II [IEA][IMP][TAS] transmembrane receptor protein serine/threonine kinase activity [UNKNOWN] nucleotide binding [IEA] transforming growth factor beta binding [UNKNOWN] ATP binding [IEA] receptor signaling protein serine/threonine kinase activity [IEA] protein binding [UNKNOWN][IPI] SMAD binding [UNKNOWN] glycosaminoglycan binding [UNKNOWN] metal ion binding [IEA] protein heterodimerization activity [TAS] transferase activity [IEA] mitogen-activated protein kinase kinase kinase binding [IPI] type III transforming growth factor beta receptor binding [UNKNOWN] type I transforming growth factor beta receptor binding [UNKNOWN] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MGRGLLRGLW PLHIVLWTRI ASTIPPHVPK SVNSDLMAGD NSGAVKLPQL CKFCDVTLST 60 61 CDNQKSCMSN CSVTSICEKP QEVCVAVWRK NDKNITLETV CHDPKFTYHG FTLEDATSPT 120 121 CVMKEKKRAG ETFFMCSCNT EECNDYIIFN EEYTTSSPDL LLVIIQVTGV SLLPPLGIAI 180 181 AVIAIFYCYR VHRQQKLSPS WESSKPRKLM DFSDNCAIIL EDDRSDISST CANNINHNTE 240 241 LLPIELDTLV GKGRFAEVYK AKLKQNTSEQ FETVAVKIFP YEEYSSWKTE KDIFSDINLK 300 301 HENILQFLTA EERKTEMGKQ YWLITAFHAK GNLQEYLTRH VISWEDLRKL GSSLARGIAH 360 361 LHSDHTPCGR PKMPIVHRDL KSSNILVKND LTCCLCDFGL SLRLDPTLSV DDLANSGQVG 420 421 TARYMAPEVL ESRMNLENME SFKQTDVYSM ALVLWEMTSR CNAVGEVKDY EPPFGSKVRE 480 481 HPCVESMKDN VLRDRGRPEI PSFWLNHQGI QIVCETLTEC WDHDPEARLT AQCVAERFSE 540 541 LEHPDRLSGR SCSQEKIPED GSLNTTK |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.16 |
Source: Reynolds et al. (2008)