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Protein Overview: CHK1_RAT

General Information:
Name(s) found: CHK1_RAT [Swiss-Prot]
Description(s) found:
Found 21 descriptions.
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  • Serine/threonine-protein kinase Chk1 OS=Rattus norvegicus GN=Chek1 PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 476 amino acids

    Gene Ontology:
    Cellular Component: replication fork [UNKNOWN][IEA]
    chromosome, telomeric region [UNKNOWN]
    nucleus [UNKNOWN][IEA]
    cytoskeleton [IEA]
    microtubule organizing center [IEA]
    cytoplasm [IEA]
    cellular_component [ND]
    nucleoplasm [UNKNOWN]
    Biological Process: regulation of S phase [IMP]
    DNA repair [UNKNOWN][IEA]
    DNA replication [UNKNOWN]
    protein amino acid phosphorylation [UNKNOWN][IDA]
    response to DNA damage stimulus [UNKNOWN]
    DNA damage induced protein phosphorylation [IMP]
    cell cycle [IEA]
    DNA damage checkpoint [UNKNOWN]
    G2/M transition of mitotic cell cycle [UNKNOWN][IEA]
    cellular response to organic substance [IEP]
    senescence [UNKNOWN]
    G2/M transition DNA damage checkpoint [IMP]
    cellular response to caffeine [IEP]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    protein binding [UNKNOWN][IEA]
    protein kinase activity [UNKNOWN][IDA]
    protein serine/threonine kinase activity [UNKNOWN][IEA]
    transferase activity [IEA]
    kinase activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVPFVEDWD LVQTLGEGAY GEVQLAVNRI TEEAVAVKIV DMKRAIDCPE NIKKEICINK  60
   61 MLNHENVVKF YGHRREGNIQ YLFLEYCSGG ELFDRIEPDI GMPEQDAQRF FHQLMAGVVY 120
  121 LHGIGITHRD IKPENLLLDE RDNLKISDFG LATVFRHNNR ERLLNKMCGT LPYVAPELLK 180
  181 RKEFHAEPVD VWSCGIVLTA MLAGELPWDQ PSDSCQEYSD WKEKKTYLNP WKKIDSAPLA 240
  241 LLHKILVENP SARITIPDIK KDRWYNKPLN RGAKRPRATS GGMSESSSGF SKHIHSNLDF 300
  301 SPINSGSSEE NVKFSSSQPE PRTGLSLWDT GPSNVDKLVQ GISFSQPTCP DHMLVNSQLL 360
  361 GTPGSSQNPW QRLVKRMTRF FTKLDADKSY QCLKETFEKL GYQWKKSCMN QVTVSTMDRR 420
  421 NNKLIFKINL VEMDEKILVD FRLSKGDGLE FKRHFLKIKG KLSDIVSSQK VWFPVT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle