Protein Overview: DPYD_RAT

General Information:
Name(s) found:	DPYD_RAT [Swiss-Prot]
Description(s) found: Found 15 descriptions. SHOW ALL	Dihydropyrimidine dehydrogenase [NADP(+)] OS=Rattus norvegicus GN=Dpyd PE=2 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	1025 amino acids
Gene Ontology:
Cellular Component:	soluble fraction [IDA] cytoplasm [UNKNOWN][IEA][ISS] cytosol [UNKNOWN][IDA]
Biological Process:	purine base catabolic process [UNKNOWN] UMP biosynthetic process [IEA] uracil catabolic process [UNKNOWN][ISS] response to nutrient [IDA] thymine catabolic process [UNKNOWN] circadian rhythm [IDA] thymidine catabolic process [UNKNOWN][ISS] pyrimidine base catabolic process [UNKNOWN][IDA][TAS] 'de novo' pyrimidine base biosynthetic process [IEA] response to drug [IDA] response to glucocorticoid stimulus [IEP] uracil metabolic process [IDA] oxidation reduction [IEA]
Molecular Function:	NADP or NADPH binding [IDA] protein homodimerization activity [UNKNOWN][IDA] oxidoreductase activity [IEA] metal ion binding [IEA] electron carrier activity [IEA] dihydropyrimidine dehydrogenase (NADP+) activity [UNKNOWN][IDA][ISS] 4 iron, 4 sulfur cluster binding [IEA] binding [IEA] iron-sulfur cluster binding [IEA] uracil binding [IDA] dihydroorotate oxidase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGVLSRDAP DIESILALNP RIQAHATLRS TMAKKLDKKH WKRNTDKNCF ICEKLENNFD  60
   61 DIKHTTLGER GALREAVRCL KCADAPCQKS CPTSLDIKSF ITSIANKNYY GAAKLIFSDN 120
  121 PLGLTCGMVC PTSDLCVGGC NLHATEEGPI NIGGLQQFAT EVFKAMNIPQ IRSPLLPPPE 180
  181 HMPEAYSAKI ALFGAGPASI SCASFLARLG YSDITIFEKQ EYVGGLSTSE IPQFRLPYDV 240
  241 VNFEIELMKD LGVKIICGKS ISTDEMTLST LKENGYKAAF IGIGLPEPKK DHIFQGLTQV 300
  301 QGFYTSKDFL PLVAKGSKPG MCACHSPLPS VRGAVIVLGA GDTAFDCATS ALRCGARRVF 360
  361 IVFRKGFANI RAVPEEMELA KEEKCEFLPF LSPRKVIVKD GKIVGMQFVR TEQDETGNWV 420
  421 EDEEQIVRLK ADVVISPFGS VLDDPKVIEA LSPIKFNRWG LPEVNPETMQ TSEPWVFAGG 480
  481 DVVGMANTTV ESVNDGKQAS WYIHEYIQAQ YGALVPSQPT LPLFYTPVDL VDISVEMAGL 540
  541 RFPNPFGLAS ATPATSTPMI RRAFEAGWGF ALTKTFSLDK DIVTNVSPRI IRGTTSGPLY 600
  601 GPGQSSFLNI ELISEKTAAY WCHSVTELKA DFPDNILIAS IMCSYNKNDW MELSKMAEAS 660
  661 GADALELNLS CPHGMGERGM GLACGQDPEL VRNICRWVRQ SVRVPFFAKL TPNVTDIVSI 720
  721 ARAAKEGGAD GVTATNTVSG LMGLKADGSP WPSVGSGKRT TYGGVSGTTI RPIALRAVTA 780
  781 IARALPGFPI LATGGIDSAE SGLQFLHSGA SVLQVCSAIQ NQDFTVIEDY CTGLKALLYL 840
  841 KSIEELSDWD GQSPPTMSHQ KGKPVPHIAE LMGQKLPSFG PYLERRKKIL AASKIRENDQ 900
  901 NRACSPLQRK HFNSQKPIPA IKDVIGKSLQ YLGTFGELNI MEQVVALIDE EMCINCGKCY 960
  961 MTCNDSGYQA IQFDPETHLP TVSDTCTGCT LCLSVCPIMD CIRMVSRATP YEPKRGLPLA1020
 1021 VKPVC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.86

Protein Overview: DPYD_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: