Protein Overview: GRIK5_RAT

General Information:
Name(s) found:	GRIK5_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|JH0592 glutamate receptor chain KA-2 precursor - rat [NCBI NR] gi\|56510\|emb\|CAA77667.1\| kainate receptor [Rattus norvegicus] [NCBI NR] gi\|3287840\|sp\|Q63273.1\|GRIK5_RAT RecName: Full=Glutamate receptor, ionotropic kainate 5; AltName: Full=Glutamate receptor KA-2; Short=KA2; Flags: Precursor [NCBI NR] gi\|149056617\|gb\|EDM08048.1\| glutamate receptor, ionotropic, kainate 5, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149056616\|gb\|EDM08047.1\| glutamate receptor, ionotropic, kainate 5, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|13994161\|ref\|NP_113696.1\| glutamate receptor, ionotropic, kainate 5 precursor [Rattus norvegicus] [NCBI NR] Glutamate receptor ionotropic, kainate 5 OS=Rattus norvegicus GN=Grik5 PE=1 SV=1 [Swiss-Prot] (Q63273) Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) [Swiss-Prot] Ensembl_locations(Chr-bp):1-77452972 Glutamate receptor, ionotropic kainate 5 precursor [hmr_yeast5_DM3-1_pombe.fasta] glutamate receptor KA2 precursor [HMR_022704-rand.fasta] glutamate receptor KA2 precursor [Rattus norvegicus]gi\|56510\|emb\|CAA77667.1\| kainate receptor [Rattus norvegicus]gi\|3287840\|sp\|Q63273\|GLK5_RAT Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2)gi\|92293\|pir\|\|JH0592 glutam [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Glutamate receptor, ionotropic kainate 5 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031508) glutamate receptor, ionotropic, kainate 5 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glutamate receptor KA2 precursor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glutamate receptor, ionotropic, kainate 5, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] kainate receptor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 5 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] glutamate receptor, ionotropic, kainate 5 precursor [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Grik5 Glutamate receptor, ionotropic kainate 5 [rat-ipi-250309-contam.fasta] Glutamate receptor, ionotropic kainate 5 OS=Rattus norvegicus GN=Grik5 [011711_HMR.fasta] Glutamate receptor, ionotropic kainate 5 OS=Rattus norvegicus GN=Grik5 PE=1 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	979 amino acids
Gene Ontology:
Cellular Component:	presynaptic membrane [UNKNOWN][IEA] synaptosome [IDA] neuronal cell body [IDA] synapse [IEA] ionotropic glutamate receptor complex [IDA] perikaryon [IDA] plasma membrane [UNKNOWN][IEA] membrane fraction [UNKNOWN] dendrite [IDA] terminal button [IDA] postsynaptic membrane [UNKNOWN][IEA] integral to membrane [IEA] cell junction [IEA] kainate selective glutamate receptor complex [UNKNOWN][IEA] axon [IDA]
Biological Process:	neuroprotection [IMP] ion transport [IEA] regulation of excitatory postsynaptic membrane potential [UNKNOWN][IEA] regulation of membrane potential [UNKNOWN][IEA] cellular response to glucose stimulus [IEP] synaptic transmission [IDA] regulation of synaptic vesicle fusion to presynaptic membrane [UNKNOWN][IEA] receptor clustering [IDA] establishment of localization in cell [IMP] protein retention in ER lumen [IMP] synaptic transmission, glutamatergic [UNKNOWN][IEA]
Molecular Function:	ion channel activity [IEA] identical protein binding [IPI] protein binding [IPI] kainate selective glutamate receptor activity [UNKNOWN][IDA] glutamate receptor activity [IDA] PDZ domain binding [IPI] SH3 domain binding [IMP] receptor activity [IEA] extracellular-glutamate-gated ion channel activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
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    1 MPAELLLLLI VAFANPSCQV LSSLRMAAIL DDQTVCGRGE RLALALAREQ INGIIEVPAK  60
   61 ARVEVDIFEL QRDSQYETTD TMCQILPKGV VSVLGPSSSP ASASTVSHIC GEKEIPHIKV 120
  121 GPEETPRLQY LRFASVSLYP SNEDVSLAVS RILKSFNYPS ASLICAKAEC LLRLEELVRG 180
  181 FLISKETLSV RMLDDSRDPT PLLKEIRDDK VSTIIIDANA SISHLVLRKA SELGMTSAFY 240
  241 KYILTTMDFP ILHLDGIVED SSNILGFSMF NTSHPFYPEF VRSLNMSWRE NCEASTYPGP 300
  301 ALSAALMFDA VHVVVSAVRE LNRSQEIGVK PLACTSANIW PHGTSLMNYL RMVEYDGLTG 360
  361 RVEFNSKGQR TNYTLRILEK SRQGHREIGV WYSNRTLAMN ATTLDINLSQ TLANKTLVVT 420
  421 TILENPYVMR RPNFQALSGN ERFEGFCVDM LRELAELLRF RYRLRLVEDG LYGAPEPNGS 480
  481 WTGMVGELIN RKADLAVAAF TITAEREKVI DFSKPFMTLG ISILYRVHMG RKPGYFSFLD 540
  541 PFSPAVWLFM LLAYLAVSCV LFLAARLSPY EWYNPHPCLR ARPHILENQY TLGNSLWFPV 600
  601 GGFMQQGSEI MPRALSTRCV SGVWWAFTLI IISSYTANLA AFLTVQRMEV PVESADDLAD 660
  661 QTNIEYGTIH AGSTMTFFQN SRYQTYQRMW NYMQSKQPSV FVKSTEEGIA RVLNSRYAFL 720
  721 LESTMNEYHR RLNCNLTQIG GLLDTKGYGI GMPLGSPFRD EITLAILQLQ ENNRLEILKR 780
  781 KWWEGGRCPK EEDHRAKGLG MENIGGIFVV LICGLIIAVF VAVMEFIWST RRSAESEEVS 840
  841 VCQEMLQELR HAVSCRKTSR SRRRRRPGGP SRALLSLRAV REMRLSNGKL YSAGAGGDAG 900
  901 AHGGPQRLLD DPGPPGGPRP QAPTPCTHVR VCQECRRIQA LRASGAGAPP RGLGTPAEAT 960
  961 SPPRPRPGPT GPRELTEHE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: GRIK5_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: