General Information: |
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Name(s) found: |
NRG1_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 662 amino acids |
Gene Ontology: |
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Cellular Component: |
integral to plasma membrane
[UNKNOWN]
extracellular space [UNKNOWN] cytoplasm [UNKNOWN] integral to membrane [IEA] synapse [UNKNOWN] extracellular region [IEA] plasma membrane [UNKNOWN][IEA] apical plasma membrane [UNKNOWN] |
Biological Process: |
activation of transmembrane receptor protein tyrosine kinase activity
[UNKNOWN]
cell proliferation [UNKNOWN] embryonic development [IEA] positive regulation of cardiac muscle cell proliferation [UNKNOWN] ventricular cardiac muscle cell differentiation [UNKNOWN] nervous system development [UNKNOWN] positive regulation of Ras protein signal transduction [UNKNOWN] myelination [IEP] positive regulation of cell adhesion [UNKNOWN] cellular protein complex disassembly [UNKNOWN] negative regulation of secretion [UNKNOWN] MAPKKK cascade [UNKNOWN] heart development [UNKNOWN] positive regulation of cell growth [UNKNOWN] wound healing [UNKNOWN] locomotory behavior [UNKNOWN] anti-apoptosis [UNKNOWN] regulation of cell differentiation [UNKNOWN] neuron fate commitment [UNKNOWN] cell migration [UNKNOWN] cell morphogenesis [UNKNOWN] regulation of protein heterodimerization activity [UNKNOWN] transmembrane receptor protein tyrosine kinase signaling pathway [UNKNOWN] peripheral nervous system development [UNKNOWN] neurotransmitter receptor metabolic process [UNKNOWN] regulation of blood pressure [IEP] muscle organ development [UNKNOWN] synapse assembly [UNKNOWN] positive regulation of protein kinase activity [UNKNOWN] negative regulation of transcription [UNKNOWN] negative regulation of cardiac muscle cell apoptosis [UNKNOWN] glucose transport [IMP] glial cell differentiation [UNKNOWN] |
Molecular Function: |
growth factor activity
[UNKNOWN][IEA]
transcription cofactor activity [UNKNOWN] protein binding [UNKNOWN] ErbB-2 class receptor binding [UNKNOWN] protein tyrosine kinase activator activity [UNKNOWN] ErbB-3 class receptor binding [UNKNOWN][IMP] receptor binding [UNKNOWN][IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MSERKEGRGK GKGKKKDRGS RGKPGPAEGD PSPALPPRLK EMKSQESAAG SKLVLRCETS 60 61 SEYSSLRFKW FKNGNELNRK NKPENIKIQK KPGKSELRIN KASLADSGEY MCKVISKLGN 120 121 DSASANITIV ESNEFITGMP ASTETAYVSS ESPIRISVST EGANTSSSTS TSTTGTSHLI 180 181 KCAEKEKTFC VNGGECFTVK DLSNPSRYLC KCPNEFTGDR CQNYVMASFY MTSRRKRQET 240 241 EKPLERKLDH SLVKESKAEE LYQKRVLTIT GICIALLVVG IMCVVAYCKT KKQRQKLHDR 300 301 LRQSLRSERS NLVNIANGPH HPNPPPENVQ LVNQYVSKNV ISSEHIVERE VETSFSTSHY 360 361 TSTAHHSTTV TQTPSHSWSN GHTESVISES NSVIMMSSVE NSRHSSPAGG PRGRLHGLGG 420 421 PRDNSFLRHA RETPDSYRDS PHSERYVSAM TTPARMSPVD FHTPSSPKSP PSEMSPPVSS 480 481 MTVSMPSVAV SPFVEEERPL LLVTPPRLRE KKYDHHPQQL NSFHHNPAHQ STSLPPSPLR 540 541 IVEDEEYETT QEYESVQEPV KKVTNSRRAK RTKPNGHIAN RLEMDSNTSS VSSNSESETE 600 601 DERVGEDTPF LGIQNPLAAS LEVAPAFRLA ESRTNPAGRF STQEELQARL SSVIANQDPI 660 661 AV |
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