General Information: |
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Name(s) found: |
CNTF_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 200 amino acids |
Gene Ontology: |
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Cellular Component: |
nucleus
[IDA]
extracellular space [UNKNOWN][IEA] cytoplasm [IEA] cell projection cytoplasm [IDA] cytosol [IDA] neuronal cell body [IDA] axon [IDA] |
Biological Process: |
neuroprotection
[IDA]
positive regulation of phosphoinositide 3-kinase cascade [IDA] positive regulation of tyrosine phosphorylation of Stat3 protein [UNKNOWN][IDA] multicellular organismal development [IEA] regulation of resting membrane potential [IDA] positive regulation of cell proliferation [UNKNOWN][IDA] nervous system development [IDA] positive regulation of hormone secretion [IDA] protein heterooligomerization [IPI] positive regulation of MAPKKK cascade [IDA] negative regulation of photoreceptor cell differentiation [UNKNOWN][IEA] muscle organ morphogenesis [UNKNOWN][IEA] neuron development [UNKNOWN][IEA] growth [IEA] regulation of retinal cell programmed cell death [UNKNOWN][IEA] JAK-STAT cascade [IDA] negative regulation of neuron apoptosis [IDA] positive regulation of JAK-STAT cascade [IDA] astrocyte activation [IDA] positive regulation of cell growth [IDA] positive regulation of axon regeneration [IDA] ciliary neurotrophic factor-mediated signaling pathway [UNKNOWN][IEA] cell differentiation [IEA] membrane hyperpolarization [IDA] |
Molecular Function: |
growth factor activity
[UNKNOWN][TAS]
protein binding [UNKNOWN][IEA] cytokine activity [IDA] ciliary neurotrophic factor receptor binding [IPI] interleukin-6 receptor binding [UNKNOWN][IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MAFAEQTPLT LHRRDLCSRS IWLARKIRSD LTALMESYVK HQGLNKNINL DSVDGVPVAS 60 61 TDRWSEMTEA ERLQENLQAY RTFQGMLTKL LEDQRVHFTP TEGDFHQAIH TLMLQVSAFA 120 121 YQLEELMVLL EQKIPENEAD GMPATVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRVIS 180 181 SHQMGISALE SHYGAKDKQM |
SHOWING SINGLE HITS. [ Hide Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)