General Information: |
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Name(s) found: |
CCR2_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 373 amino acids |
Gene Ontology: |
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Cellular Component: |
dendrite
[IDA]
perinuclear region of cytoplasm [IDA] cytoplasm [UNKNOWN] integral to membrane [IEA] cytosol [IDA] neuronal cell body [IDA] perikaryon [IDA] plasma membrane [UNKNOWN][IEA] |
Biological Process: |
negative regulation of angiogenesis
[IEA]
G-protein coupled receptor protein signaling pathway [IMP] signal transduction [IEA] hemopoiesis [UNKNOWN][IEA] positive regulation of MAPKKK cascade [IDA] cellular calcium ion homeostasis [IDA] cellular defense response [UNKNOWN][IEA] inflammatory response [UNKNOWN][IDA] blood vessel remodeling [IEP] immune response [UNKNOWN] inflammatory response to antigenic stimulus [IEP] cytokine-mediated signaling pathway [UNKNOWN][IMP] chemokine-mediated signaling pathway [IMP] humoral immune response [UNKNOWN][IEA] positive regulation of macrophage chemotaxis [IEA] sensory perception of pain [UNKNOWN][IEA] regulation of vascular endothelial growth factor production [IEA] regulation of cell migration [UNKNOWN][IEA] |
Molecular Function: |
C-C chemokine binding
[IEP][IMP]
G-protein coupled receptor activity [IEA] chemokine binding [IMP] protein binding [UNKNOWN] protein homodimerization activity [IDA] CCR2 chemokine receptor binding [UNKNOWN] C-C chemokine receptor activity [UNKNOWN][IMP] receptor activity [IEA] cytokine binding [UNKNOWN] chemokine receptor activity [IEP] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MEDSNMLPQF IHGILSTSHS LFPRSIQELD EGATTPYDYD DGEPCHKTSV KQIGAWILPP 60 61 LYSLVFIFGF VGNMLVIIIL ISCKKLKSMT DIYLFNLAIS DLLFLLTLPF WAHYAANEWV 120 121 FGNIMCKLFT GLYHIGYFGG IFFIILLTID RYLAIVHAVF ALKARTVTFG VITSVVTWVV 180 181 AVFASLPGII FTKSEQEDDQ HTCGPYFPTI WKNFQTIMRN ILSLILPLLV MVICYSGILH 240 241 TLFRCRNEKK RHRAVRLIFA IMIVYFLFWT PYNIVLFLTT FQEFLGMSNC VVDMHLDQAM 300 301 QVTETLGMTH CCVNPIIYAF VGEKFRRYLS IFFRKHIAKN LCKQCPVFYR ETADRVSSTF 360 361 TPSTGEQEVS VGL |
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