Protein Overview: APAF_RAT

General Information:
Name(s) found:	APAF_RAT [Swiss-Prot]
Description(s) found: Found 20 descriptions. SHOW ALL	Apoptotic protease-activating factor 1 OS=Rattus norvegicus GN=Apaf1 PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	1249 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN] soluble fraction [UNKNOWN] cytoplasm [IEA] cytosol [UNKNOWN] intracellular [IEA]
Biological Process:	forebrain development [UNKNOWN] neural tube closure [UNKNOWN] induction of apoptosis [IDA] multicellular organismal development [UNKNOWN] DNA fragmentation involved in apoptosis [UNKNOWN] regulation of apoptosis [IEA] activation of caspase activity [UNKNOWN] brain development [UNKNOWN] defense response [IEA] activation of caspase activity by cytochrome c [UNKNOWN] glial cell apoptosis [IEP] neuron apoptosis [UNKNOWN]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] identical protein binding [UNKNOWN] protein binding [UNKNOWN][IEA] apoptotic protease activator activity [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAKARNCLL QHKEALEKDI KTSYIMDHMI SNGVLTVVEE EKVKSQATQY QRAAALIKMI  60
   61 LNKDNYAYIS FYNALLHEGY KDLAGLLHSG LPLVSSSSGK DTDGGNTSFV RTVLCEGGVP 120
  121 QRPVIFVTRK KLVSAIQQKL WKLNGEPGWV TIYGMAGCGK SVLAAEAVRD HALLEGCFSG 180
  181 GVHWVSIGKQ DKSGLLMKLQ NLCTRLGQEE SFSQRLPLNI EEAKDRLRVL MLRKHPRSLL 240
  241 ILDDVWDPWV LKAFDNQCQI LLTTRDKSVT DSVMGPKYVI PVESGLGKEK GLEILSLFVN 300
  301 MKKEDLPVEA HSIIKECKGS PLVVSLVGAL LRDFPNRWAY YLRQLQNKQF KRIRKSSSYD 360
  361 YEALDEAMSI SVEMLREDIK DYYTDLSILQ KDVKVPTKVL CVLWDLETEE VEDILQEFVN 420
  421 KSLLFCNRNG KSFCYYLHDL QVDFLTEKNR SQLQDLHRKM VTQFQRYHQP HTLSPGQEDC 480
  481 MYWYNFLAYH MASAGMHKEL CALMFSLDWI KAKTELVGPA HLIHEFVEYR HILDEKDCAV 540
  541 CENFQEFLSL NGHLLGRQPF PNIVQLGLCE PETSEVYQQA KLQAKQEVDT GRLYLEWINK 600
  601 KTIKNLSRLV VRPHTDAVYH ACFSQDGQRI ASCGADKTLQ VFKAETGEKL LDIKAHEDEV 660
  661 LCCAFSSDDS YIATCSVDKK VKIWDSGTGK LVHTYEEHSE QVNCCHFTNK SNHLLLATGS 720
  721 NDSFLKLWDL NQKECRNTMF GHTNSVTHCR FSPDDELLAS CSADGTLKLW DVRSANEKKS 780
  781 INVKRFFLSS EDPPEDVEVI VKCCSWSADG DRIIVAAKNK VLLLDIHTSG LLTEIHTGHH 840
  841 STIQYCDFSP YDHLAVIALS QYCVELWNID SRVKVADCRG HLSWVHGVMF SPDGSSFLTA 900
  901 SDDQTIRVWE TRKVCKNSAI VLKQEIDVVF QENEMMVLAV DNIRGLQLIA GKTGQIDYLP 960
  961 EAQVSCCCLS PHLEYVAFGD EEGAIKIIEL PNNRVFSSGI GHKKAVRHIQ FTADGKTLIS1020
 1021 SSEDSVIQVW NWQTEEYVFL QAHQETVKDF RLLRDSRLLS WSFDGTVKVW NVITGRIERD1080
 1081 FTCHQGTVLS CAISSDATKF SSTSADKTAK IWSFELPSPL HELKGHNSCV RCSAFSLDGI1140
 1141 LLATGDDNGE IRIWNVSDGQ LLHLCAPISI EEGTATHGGW VTDVCFSPDR KMLVSAGGYL1200
 1201 KWWNVVTGES SQTFYTNGTN LKKIHVSPDF RTYVTVDNLG ILYILQVLE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: APAF_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: