Protein Overview: CN5A_MOUSE, PDE5...

General Information:
Name(s) found:	PDE5A_MOUSE [Swiss-Prot] CN5A_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|37077162\|sp\|Q8CG03.1\|PDE5A_MOUSE RecName: Full=cGMP-specific 3',5'-cyclic phosphodiesterase; AltName: Full=cGMP-binding cGMP-specific phosphodiesterase; Short=CGB-PDE [NCBI NR] gi\|23510317\|ref\|NP_700471.1\| phosphodiesterase 5A [Mus musculus] [NCBI NR] gi\|23305887\|gb\|AAN17330.1\| cGMP-binding/cGMP-specific phosphodiesterase [Mus musculus] [NCBI NR] cGMP-specific 3',5'-cyclic phosphodiesterase OS=Mus musculus GN=Pde5a PE=1 SV=1 [Swiss-Prot] (Q8CG03) cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase) [Swiss-Prot] Ensembl_locations(Chr-bp):7-29115428 cGMP-binding/cGMP-specific phosphodiesterase [hmr_yeast5_DM3-1_pombe.fasta] phosphodiesterase 5A, cGMP-specific; cGMP-binding/cGMP-specific phosphodiesterase [HMR_022704-rand.fasta] cGMP-specific 3',5'-cyclic phosphodiesterase [ipi.MOUSE.v3.06.fasta] phosphodiesterase 5A, cGMP-specific [Mus musculus]gi\|23305887\|gb\|AAN17330.1\| cGMP-binding/cGMP-specific phosphodiesterase [Mus musculus]gi\|37077162\|sp\|Q8CG03\|CN5A_MOUSE cGMP-specific 3',5'-cyclic phosphodiesterase (CGB-PDE) (cGMP-binding cGMP-specific p [nrdb_11152004_Chlamydomonas] Tax_Id=10090 cGMP-specific 3',5'-cyclic phosphodiesterase [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] phosphodiesterase 5A, cGMP-specific [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] cGMP-specific 3',5'-cyclic phosphodiesterase (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cGMP-binding/cGMP-specific phosphodiesterase [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Pde5a cGMP-specific 3',5'-cyclic phosphodiesterase [mouse-ipi-250309-contam.fasta] phosphodiesterase 5A [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta] cGMP-specific 3',5'-cyclic phosphodiesterase (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase) [nr-271106-contam.fasta] Tax_Id=10090 Gene_Symbol=Pde5a cGMP-specific 3',5'-cyclic phosphodiesterase ENSMUSG00000053965 IPI00229355 IPI00465762 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00229355.1\|SWISS-PROT:Q8CG03\|TREMBL:Q0VBW0\|ENSEMBL:ENSMUSP00000069011\|REFSEQ:NP_700471 Tax_Id=10090 Gene_Symbol=Pde5a cGMP-specific 3',5'-cyclic phosphodiesterase [ipi.MOUSE.fasta.20090209] cGMP-specific 3',5'-cyclic phosphodiesterase OS=Mus musculus GN=Pde5a [011711_HMR.fasta]
Organism:	Mus musculus
Length:	865 amino acids
Gene Ontology:
Cellular Component:	cytosol [UNKNOWN]
Biological Process:	regulation of the force of heart contraction [UNKNOWN] short-term memory [UNKNOWN] positive regulation of chronic inflammatory response [UNKNOWN] cGMP catabolic process [IDA] signal transduction [IEA] positive regulation of apoptosis [UNKNOWN] positive regulation of vasoconstriction [UNKNOWN]
Molecular Function:	nucleotide binding [IEA] catalytic activity [IEA] metal ion binding [IEA] 3',5'-cyclic-GMP phosphodiesterase activity [UNKNOWN] cGMP binding [IDA] cyclic-nucleotide phosphodiesterase activity [IDA] hydrolase activity [IEA] 3',5'-cyclic-nucleotide phosphodiesterase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERAGPNSVR SQQQRDPDWV EAWLDDHRDF TFSYFIRKAT RDMVNAWFSE RVHNIPVCKE  60
   61 GIRAHTESCS CSLQQSPHAD NTTPGAPARK ISASEFDRPL RPIVVKDSEG TVSFLSDSGK 120
  121 KEQMPLTPPR FDSDEGDQCS RLLELVKDIS SHLDVTALCH KIFLHIHGLI SADRYTLFLV 180
  181 CEDSSKDKFL ISRLFDVAEG STLEEASNNC IRLEWNKGIV GHVAAFGEPL NIKDAYEDPR 240
  241 FNAEVDQITG YKTQSILCMP IKNHREEVVG VAQAINKKSG NGGTFTEKDE KDFAAYLAFC 300
  301 GIVLHNAQLY ETSLLENKRN QVLLDLASLI FEEQQSLEVI LKKIAATIIS FMQVQKCTIF 360
  361 IVDEDCPDSF SRVFHMECEE VGKPSDPLTR EQDANKINYM YAQYVKNTME PLNIPDVTKD 420
  421 KRFPWTNENM GHVNTPCIGS LLCTPIKNGK KNKVIGVCQL VNKMEENTGK IKAFNQNDEQ 480
  481 FLEAFVIFCG LGIQNTQMYE AVERAMAKQM VTLEVLSYHA SAAEEETREL QALSAAVVPS 540
  541 AQTLKITDFS FSDFELSDLE TALCTIRMFT DLNLVQNFQM KHEVLCRWIL SVKKNYRKNV 600
  601 AYHNWRHAFN TAQCMFAALK AGKIQNKLTD LETLALLIAA LSHDLDHRGV NNSYIQRSEH 660
  661 PLAQLYCHSI MEHHHFDQCL MILNSPGNQI LSGLSIDEYK TTLKIIKQAI LATDLALYIK 720
  721 RRGEFFELIR KNQFSFEDPL QKELFLAMLM TACDLSAITK PWPIQQRIAE LVAAEFFDQG 780
  781 DRERKELNME PADLMNREKK NKIPSMQVGF IDAICLQLYE ALTHVSEDCL PLLDGCRKNR 840
  841 QKWQALAEQQ EKMLLNGESS QGKRD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: CN5A_MOUSE, PDE5...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: