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Protein Overview: ERR1, ERR2

General Information:
Name(s) found: ERR2 / YPL281C [SGD]
ERR1 / YOR393W [SGD]
Description(s) found:
Found 38 descriptions.
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  • Protein of unknown function, has similarity to enolases [SGD]
  • Protein of unknown function, has similarity to enolases [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 437 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: phosphopyruvate hydratase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSITKVHART VYDSRGNPTV EVEITTENGL FRAIVPSGAS TGIHEAVELR DGNKSEWMGK  60
   61 GVTKAVSNVN SIIGPALIKS ELCVTNQKGI DELMISLDGT SNKSRLGANA ILGVSLCVAR 120
  121 AAAAQKGITL YKYIAELADA RQDPFVIPVP FFNVLNGGAH AGGSLAMQEF KIAPVGAQSF 180
  181 AEAMRMGSEV YHHLKILAKE QYGPSAGNVG DEGGVAPDID TAEDALDMIV EAINICGYEG 240
  241 RVKVGIDSAP SVFYKDGKYD LNFKEPNSDP SHWLSPAQLA EYYHSLLKKY PIISLEDPYA 300
  301 EDDWSSWSAF LKTVNVQIIA DDLTCTNKTR IARAIEEKCA NTLLLKLNQI GTLTESIEAA 360
  361 NQAFDAGWGV MISHRSGETE DPFIADLVVG LRCGQIKSGA LSRSERLAKY NELLRIEEEL 420
  421 GDDCIYAGHR FHDGNKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] PSI-BLAST 2800.0 Enolase
    2 View Details [128..437] PSI-BLAST 2800.0 Enolase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphopyruvate hydratase activity
    		•  10.7545435133049 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.33007926350873 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.15117039251634 bayes_pls_golite062009
  • DNA binding
    		•  1.97129250063131 bayes_pls_golite062009
  • binding
    		•  1.95079397144714 bayes_pls_golite062009
  • intramolecular lyase activity
    		•  1.72552670956901 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.36446664329679 bayes_pls_golite062009
  • transcription factor activity
    		•  1.24065454553451 bayes_pls_golite062009
  • lyase activity
    		•  0.953241510600178 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.908937887773213 bayes_pls_golite062009
  • hydro-lyase activity
    		•  0.874016693867333 bayes_pls_golite062009
  • catalytic activity
    		•  0.534516847146079 bayes_pls_golite062009
  • protein binding
    		•  0.476896736636797 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle