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Protein Overview: BAG7

General Information:
Name(s) found: BAG7 / YOR134W [SGD]
Description(s) found:
Found 29 descriptions.
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  • Rho GTPase activating protein (RhoGAP), stimulates the intrinsic GTPase activity of Rho1p, which plays a role in actin cytoskeleton organization and control of cell wall synthesis; structurally and functionally related to Sac7p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 409 amino acids

    Gene Ontology:
    Cellular Component: intracellular [TASLink to PubMed article]
    Biological Process: small GTPase mediated signal transduction [ISSLink to PubMed article]
    Molecular Function: Rho GTPase activator activity [ISSLink to PubMed article]
    signal transducer activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFNMNLLSTP SSEEGSPQNR SSSMSSVEGK KDRDTFTNLQ NEFDGKVFGV SLEESLKVAQ  60
   61 EEVIIQKSTN EIGSIPVVIA KSGKYLKENA LDTTGIFRIA GSNKRVRELQ AVFSKPPDYG 120
  121 RKFEGWCDFN VHDIATLLKR YLNSLSEPLV PLALYDIFRN PILENPKINE HKEQIIKDYE 180
  181 DIYMLLPQQN RHLILYLAAL LNLFARNEKK NLMSASNLAA IVQPSLLSHP KDEMCPKEYE 240
  241 ASRTVIEFLI LHASDIIPNT EKANKDTMPH AGTVAKFNNI TVPEMAIDSD EEDFVHPSID 300
  301 DHMLPRSRAL SDSNNFTIHH HHHHHHALFP SPIDFDNNGL SVPRSFKGRT LSAESLSPRL 360
  361 SKLLGNVGNS SNTGIKDPTE RVPRGEHKTK HKQRQSWLRR LTSPSRTQP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..145] PSI-BLAST 175.679424 Cdc42GAP
    2 View Details [146..286] PSI-BLAST 175.679424 Cdc42GAP
    3 View Details [287..409] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • GTPase regulator activity
    		•  5.23789256375467 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  5.21562004568462 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  4.91645234075732 bayes_pls_golite062009
  • GTPase activator activity
    		•  4.81440293338491 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  4.76400460221691 bayes_pls_golite062009
  • Rho GTPase activator activity
    		•  4.58620967349979 bayes_pls_golite062009
  • enzyme regulator activity
    		•  4.5322075775333 bayes_pls_golite062009
  • enzyme activator activity
    		•  4.29367232260052 bayes_pls_golite062009
  • Rac GTPase activator activity
    		•  3.29568423512865 bayes_pls_golite062009
  • binding
    		•  1.62780792681766 bayes_pls_golite062009
  • protein binding
    		•  1.21496582666968 bayes_pls_golite062009
  • GTPase binding
    		•  0.240141218420366 bayes_pls_golite062009
  • small GTPase binding
    		•  0.0713778754122761 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle