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Protein Overview: EOS1

General Information:
Name(s) found: EOS1 / YNL080C [SGD]
Description(s) found:
Found 33 descriptions.
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  • Protein involved in N-glycosylation; deletion mutation confers sensitivity to exidative stress and shows synthetic lethality with mutations in the spindle checkpoint genes BUB3 and MAD1; YNL080C is not an essential gene [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 366 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [IDALink to PubMed article]
    membrane [ISSLink to PubMed article]
    Biological Process: response to oxidative stress [IMPLink to PubMed article]
    protein amino acid N-linked glycosylation [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTWILSTGMG PHEDKYAKHE RATFKKTYSS MKTLSLNHLT AKQHMLMALC RDISLLPPLT  60
   61 YIFTSLRKAW RVSMRTSITL YEPQSLRDAF TYFWQKLNSA YDNNSSFEGA SQKAVNGDGK 120
  121 DSLLLSALTT ARASEYLLCS LWCLVSLYLS YAILDSLMVR WIVKYSTVAA ILRMFSMSLI 180
  181 IVTLELLLLS SLSPELDYFL HTWILISCVL TAVYIWQSYL TSDLRYIRNQ EGEVQEDTNV 240
  241 PEETEDYEDG EDDADEDSHV VVADESTVDV PSNDSLSDNS DGGLFPVNRP SVSHSQSPKR 300
  301 PKKYPKKAFN FTTKRTIDLY KITVLCVVPV GLASFITMLG LLRNLFIQRL DVEQLERILH 360
  361 EMHPPA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..32]
    [124..366]    		 ORFEUS 7.51 Beta chain
    2 View Details [33..123] ORFEUS 7.51 Beta chain
    3 View Details [232..366] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle