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Protein Overview: CAT2

General Information:
Name(s) found: CAT2 / YML042W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Carnitine acetyl-CoA transferase present in both mitochondria and peroxisomes, transfers activated acetyl groups to carnitine to form acetylcarnitine which can be shuttled across membranes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 670 amino acids

    Gene Ontology:
    Cellular Component: peroxisome [ISSLink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article][ISSLink to PubMed article]
    peroxisomal matrix [TAS]
    Biological Process: carnitine metabolic process [IMPLink to PubMed article]
    Molecular Function: carnitine O-acetyltransferase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRICHSRTLS NLKDLPITSR RAMHSAIVNY STQKAQFPVE TNNGEHYWAE KPNKFYQNKR  60
   61 PNFQGITFAK QQDLPSLPVP ELKSTLDKYL QTIRPFCNDV ETFERQQLLC KDFSEHMGPI 120
  121 LQDRLKEYAN DKRNWMAKFW DEQSYLQYND PIVPYVSYFY SHMPLPNHLS KIDNDPLIKA 180
  181 TAIISTVVKF IEAIKDESLP VEIIKGMPFC MNSFSLMFNT SRLPGKPEDN QDTNIFYSVY 240
  241 ENNFVTIAYK GKFYKLMTHD GNDKPLSENE IWRQLYSVVF QGSQSDPKLG GIGSLTSLPR 300
  301 DQWREVHLEL MKDPISQDSL ETIHKSSFML CLDLDQSPVT LEEKSRNCWH GDGINRFYDK 360
  361 SLQFLVTGNG SSGFLAEHSK MDGTPTLFLN NYVCQQLNKL DVDDFMRKVI TPSSTVAMKP 420
  421 MELPFIITPK IHKAIESAQL QFKETIGEHD LRVWHYNKYG KTFIKRHGMS PDAFIQQVIQ 480
  481 LAVFKYLKRQ LPTYEAASTR KYFKGRTETG RSVSTASLEF VSKWQNGDVP IAEKIQALKH 540
  541 SAKEHSTYLK NAANGNGVDR HFFGLKNMLK SNDDQIPPLF KDPLFNYSST WLISTSQLSS 600
  601 EYFDGYGWSQ VNDNGFGLAY MLNNEWLHIN IVNKPAKSGA SVNRLHYYLS QAADEIFDAL 660
  661 ENENKRKAKL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) CAT2 MLS1 POT1 POX1 YAT1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen NUP2 CAT2 1 Unpublished Fields Lab Data
    View Screen NAF1 CAT2 1 Hazbun TR, et al. (2003)
    View Screen RAD17 CAT2 1 Unpublished Fields Lab Data
    View Screen MET18 CAT2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..62] deduced N/A No confident structure predictions are available.
    2 View Details [63..265] Pfam 7.244125 Choline/Carnitine o-acyltransferase No confident structure predictions are available.
    3 View Details [266..371]
    [385..411]    		 ORFEUS 7.1 Glutamate mutase, large subunit
    4 View Details [372..384]
    [412..547]    		 ORFEUS 7.1 Glutamate mutase, large subunit
    5 View Details [548..670] ORFEUS 7.1 Glutamate mutase, large subunit


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle