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Protein Overview: VTA1

General Information:
Name(s) found: VTA1 / YLR181C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Multivesicular body (MVB) protein involved in endosomal protein sorting; regulates Vps4p activity by promoting its oligomerization; has an N-terminal Vps60- and Did2- binding domain, a linker region, and a C-terminal Vps4p binding domain [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 330 amino acids

    Gene Ontology:
    Cellular Component: endosome [IDALink to PubMed article]
    multivesicular body [IDALink to PubMed article]
    Biological Process: late endosome to vacuole transport [IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASNAARVVA TAKDFDKVGL GIIGYYLQLY AVELILSEED RSQEMTALAT ELLDTIEAFK  60
   61 KEIGGESEAE DSDKSLHVMN TLIHDQEKAK IYMLNFTMSL YNEKLKQLKD GPWDVMLKRS 120
  121 LWCCIDLFSC ILHLWKENIS ETSTNSLQKR IKYCKIYLSK LAKGEIGSSD EKTLDYADFA 180
  181 DDSEEIKDED VDHQTSDLEN NNNDKVEGLA PKDQTTSYEP VDEVPEFIDD ADSVNEEEQT 240
  241 VDKNEDAITK DEQQVVKKEV DLTRPSAPSE PAAAEHKSYT KDELTKIMDR ASKIEQIQKL 300
  301 AKYAISALNY EDLPTAKDEL TKALDLLNSI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) VPS60 VTA1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CDC13 VTA1 1 Unpublished Fields Lab Data
    View Screen PTC2 VTA1 1 Unpublished Fields Lab Data
    View Screen GPI14 VTA1 1 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data VTA1 and SNF7 Huh WK, et al. (2003)
    View Data VTA1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [85..330] ab initio 11.0 No description for 1ldvA was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle