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Protein Overview: SPO22

General Information:
Name(s) found: SPO22 / YIL073C [SGD]
Description(s) found:
Found 10 descriptions.
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  • Meiosis-specific protein essential for chromosome synapsis, involved in completion of nuclear divisions during meiosis; induced early in meiosis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 886 amino acids

    Gene Ontology:
    Cellular Component: nuclear chromosome [IDALink to PubMed article]
    Biological Process: synaptonemal complex assembly [IMPLink to PubMed article]
    synapsis [IMPLink to PubMed article]
    meiosis [IEPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAEKASDKY FNEVFCKCKI FATKLLSIHE ALFRTNTNLL RNFKCYISSF KSASEYRFDD  60
   61 LITNTQQHSE KYLQIINENV ESFSNEEKTE FKKLTFEFYL VNFQLYLSEN DLDTANIYTA 120
  121 KVNITDNSKY MDADLLIELC RMIYNSTVML KEINNPETQL VDVNIISFLK DVEKYLELPV 180
  181 ENLKSHTDYS NLKYSVLIFM ANCLVEGHPQ ASELEQCDHY LSLLQNEYPN KVDPFILAIN 240
  241 LTKRRNIVNP AETIEEILMR MIMSVDVISN FQAVIASIND LSKMNTKFSI VCLDYLLINK 300
  301 LNSKNDSKFL GKAICSRFLI TTQSKTMNDS EIAESLENFS TQMERIVSEP LTKHAISCII 360
  361 TLLWNTGKKL EKMEKYVVSI RFYKLALKDI ISQNYSDRGK IQRALQVVYN KIEDYSNTVR 420
  421 VYQDMDEVDR QSPLCQLLML QSFLADDKTE EALTCLQKIK SSEDEKSTDA LILAVAECKR 480
  481 KTDLSVQGLL MIFDKLQSKS NSQTISSTSS SQTLSILRYT LQMIVKVSEE EPLETFINYL 540
  541 PTVQKLLQKA VEFLKTVKLL NQLPPDVEKE AIYQQSVAVN EIEWFASFSY NVAVKCLVDQ 600
  601 SCESISEFPQ YCIQFIDLIP VQDFTFPKMY HFTYWRFKAT ILQLIIAKEK AKQDQHQKDW 660
  661 DIYEKSEELV NSINVMKKSS EFKDGSSLED RNTLHECFLE ALTIHLESAL MMPDQTRILD 720
  721 ILKKTELYQD SRVDALLIDI SSNMEDLPKG VLIEILETVL KRNMGPEVKE RELCSWLRIL 780
  781 LENAINLNHE VELRILDRVL KILNINQSSL QDTDGVLQTE LETIATYCWN IGVNYIIKDN 840
  841 KSNGIVWCKH SMGFANMVNE GLQEQLYSLW ESLASSANID INSIAK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] deduced N/A No confident structure predictions are available.
    2 View Details [128..131]
    [318..566]    		 ORFEUS 9.32 (+)-bornyl diphosphate synthase
    3 View Details [132..150]
    [164..172]
    [284..317]    		 ORFEUS 9.32 (+)-bornyl diphosphate synthase
    4 View Details [151..163]
    [173..283]    		 ORFEUS 9.32 (+)-bornyl diphosphate synthase
    5 View Details [567..810] ORFEUS 8.16 Transcription factor MalT domain III
    6 View Details [811..886] deduced N/A Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle