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Protein Overview: SHC1

General Information:
Name(s) found: SHC1 / YER096W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Sporulation-specific activator of Chs3p (chitin synthase III), required for the synthesis of the chitosan layer of ascospores; has similarity to Skt5p, which activates Chs3p during vegetative growth; transcriptionally induced at alkaline pH [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 512 amino acids

    Gene Ontology:
    Cellular Component: prospore membrane [IDALink to PubMed article]
    Biological Process: ascospore formation [IDALink to PubMed article]
    chitin biosynthetic process [IGILink to PubMed article]
    Molecular Function: enzyme activator activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMTICSNTP GAYPEIGAYN EVDKQLESSG FSSDSSLILN KPEVRQYWSS VSSHISRSGD  60
   61 VFTNDKEKIS SSIGEDAMDI DASPSLIEKY NSFPTRKILP EQDEFENDVE DDASSSLKEK 120
  121 SQGSCEIEIA SEISSEILNG TSADGNSEFH DFAEPPPSQN ESVALSFSQS NDLDFLNNPS 180
  181 GSGSSNDINR STSSISLPRH VSLDFNVYNS LCLTNEVTAS ESHNVAKFHL GKKNKKSLLP 240
  241 RWKTIEMYGE VVKKTQDIYS NFQYAQYILR VGLDTEKLHE LVKELEDESN SFSVDSLKEY 300
  301 LVNDAKVILK KLSAVGYPDA QYLLGDAYSS GVFGKIKNRR AFLLFSAAAK RMHIESVYRT 360
  361 AICYECGLGV TRNAPKAVNF LTFAATKNHP AAMYKLGVYS YHGLMGLPDD ILTKMDGYRW 420
  421 LRRATSMASS FVCGAPFELA NIYMTGYKDL IISDPDYAMA LYEKAAALGH TESARILEDA 480
  481 RRSGGFVSRG HPPSAQKYHK TSHEAVAAKK LI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) GIP1 SHC1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen RHO1 SHC1 2 Drees BL, et al. (2001)
    View Screen SPC97 SHC1 1 Unpublished Fields Lab Data
    View Screen EST1 SHC1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] deduced N/A No confident structure predictions are available.
    2 View Details [153..336] PSI-BLAST 4.0 Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
    3 View Details [337..447] PSI-BLAST 4.0 Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
    4 View Details [448..512] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.736853224379565 bayes_pls_golite062009
  • protein binding
    		•  0.582813988794606 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle