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Protein Overview: DHNA_ECOLI

General Information:
Name(s) found: DHNA_ECOLI [Swiss-Prot]
Description(s) found:
Found 8 descriptions.
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  • NADH dehydrogenase (EC 1.6.99.3) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 434 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTPLKKIVI VGGGAGGLEM ATQLGHKLGR KKKAKITLVD RNHSHLWKPL LHEVATGSLD  60
   61 EGVDALSYLA HARNHGFQFQ LGSVIDIDRE AKTITIAELR DEKGELLVPE RKIAYDTLVM 120
  121 ALGSTSNDFN TPGVKENCIF LDNPHQARRF HQEMLNLFLK YSANLGANGK VNIAIVGGGA 180
  181 TGVELSAELH NAVKQLHSYG YKGLTNEALN VTLVEAGERI LPALPPRISA AAHNELTKLG 240
  241 VRVLTQTMVT SADEGGLHTK DGEYIEADLM VWAAGIKAPD FLKDIGGLET NRINQLVVEP 300
  301 TLQTTRDPDI YAIGDCASCP RPEGGFVPPR AQAAHQMATC AMNNILAQMN GKPLKNYQYK 360
  361 DHGSLVSLSN FSTVGSLMGN LTRGSMMIEG RIARFVYISL YRMHQIALHG YFKTGLMMLV 420
  421 GSINRVIRPR LKLH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..434] PSI-BLAST 72.154902 Dihydrolipoamide dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on NADH or NADPH
    		•  7.86778387378753 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.83215507169904 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  4.19923051777224 bayes_pls_golite062009
  • dihydrolipoyl dehydrogenase activity
    		•  4.08166950447814 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  4.05603184984386 bayes_pls_golite062009
  • NADH dehydrogenase activity
    		•  3.68406278988218 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  3.50748163367583 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.32472671529283 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.16108349803474 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor
    		•  2.95007671227328 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.81614304979011 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.67270952915475 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  2.61710146943904 bayes_pls_golite062009
  • catalytic activity
    		•  2.35839632763616 bayes_pls_golite062009
  • protein binding
    		•  1.21627488765992 bayes_pls_golite062009
  • binding
    		•  1.07739303382566 bayes_pls_golite062009
  • oxygen-dependent protoporphyrinogen oxidase activity
    		•  0.84508368783381 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  0.7227919966299 bayes_pls_golite062009
  • NADPH-adrenodoxin reductase activity
    		•  0.689874846468951 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  0.421557797391339 bayes_pls_golite062009
  • glutathione-disulfide reductase activity
    		•  0.33334782799369 bayes_pls_golite062009
  • lipoamide binding
    		•  0.193025676337591 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
    		•  0.18455498413733 bayes_pls_golite062009
  • succinate dehydrogenase activity
    		•  0.110826254138262 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.34

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle