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Protein Overview: DENR_YEAST

General Information:
Name(s) found: DENR_YEAST [Swiss-Prot]
Description(s) found:
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  • Translation machinery-associated protein 22 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TMA22 PE=1 SV=1 [Swiss-Prot]
  • Protein of unknown function; associates with ribosomes and has a putative RNA binding domain; interacts with Tma20p; similar to human GRAP and human DRP1, which interacts with human Tma20p homolog MCT-1 [Saccharomyces cerevisiae] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 198 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLREVIYCGI CSYPPEYCEF SGKLKRCKVW LSENHADLYA KLYGTDDNTQ EVEAVTNKLA  60
   61 ESSIGEAREE KLEKDLLKIQ KKQENREQRE LAKKLSSKVI IKREARTKRK FIVAISGLEV 120
  121 FDIDMKKLAK TFASRFATGC SVSKNAEKKE EVVIQGDVMD EVETYIHSLL EEKGLKDVKV 180
  181 ETIDAKKKKK PAAEGAAK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..62] deduced N/A No confident structure predictions are available.
    2 View Details [63..198] PSI-BLAST 20.221849 YciH

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.36535619829821 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.221356879029422 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.213614307171087 bayes_pls_golite062009
  • protein binding
    		•  0.189517592830504 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle