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View Structure Prediction Details

Protein: CAZA2_RAT
Organism: Rattus norvegicus
Length: 286 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAZA2_RAT.

Description E-value Query
Range		 Subject
Range
CAZA1_RAT - F-actin-capping protein subunit alpha-1 OS=Rattus norvegicus GN=Capza1 PE=1 SV=1
 517.0 [0..1] [286..1]
CAZA1_CHICK - F-actin-capping protein subunit alpha-1 OS=Gallus gallus GN=CAPZA1 PE=1 SV=1
 515.0 [0..1] [286..1]
CAZA1_BOVIN - F-actin-capping protein subunit alpha-1 OS=Bos taurus GN=CAPZA1 PE=2 SV=1
 515.0 [0..1] [286..1]
gi|61371588, gi|... - gi|61371588|gb|AAX43695.1| capping protein muscle Z-line alpha 1 [synthetic construct], gi|61365542|...
 514.0 [0..1] [286..1]
gi|109013601 - gi|109013601|ref|XP_001107677.1| PREDICTED: F-actin capping protein alpha-1 subunit [Macaca mulatta]
 513.0 [0..1] [286..1]
CAPZA1 - capping protein (actin filament) muscle Z-line, alpha 1
gi|123979702, gi... - gi|61355548|gb|AAX41151.1| capping protein muscle Z-line alpha 1 [synthetic construct], gi|60821852|...
 513.0 [0..1] [286..1]
gi|73981496 - gi|73981496|ref|XP_533066.2| PREDICTED: similar to capping protein (actin filament) muscle Z-line, a...
 513.0 [0..1] [286..1]
CAZA1_MOUSE - F-actin-capping protein subunit alpha-1 OS=Mus musculus GN=Capza1 PE=1 SV=4
 513.0 [0..1] [286..1]
CAZA1_PONAB - F-actin-capping protein subunit alpha-1 OS=Pongo abelii GN=CAPZA1 PE=2 SV=3
CAZA1_PONPY - F-actin-capping protein subunit alpha-1 - Pongo pygmaeus (Orangutan)
 512.0 [0..1] [286..1]

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Predicted Domain #1
Region A:
Residues: [1-286] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADLEEQLSD EEKVRIAAKF IIHAPPGEFN EVFNDVRLLL NNDNLLREGA AHAFAQYNLD  60
   61 QFTPVKIEGY EDQVLITEHG DLGNGKFLDP KNRICFKFDH LRKEATDPRP YEAENAIESW 120
  121 RTSVETALRA YVKEHYPNGV CTVYGKKVDG QQTIIACIES HQFQAKNFWN GRWRSEWKFT 180
  181 VTPSTTQVVG ILKIQVHYYE DGNVQLVSHK DIQDSLTVSN EVQTAKEFIK IVEAAENEYQ 240
  241 TAISENYQTM SDTTFKALRR QLPVTRTKID WNKILSYKIG KEMQNA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 147.0
Match: 1iznA
Description: Capz alpha-1 subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 6.56144513012007 bayes_pls_golite062009
actin filament binding 5.39928513902709 bayes_pls_golite062009
cytoskeletal protein binding 5.10504476256679 bayes_pls_golite062009
binding 2.03345990933192 bayes_pls_golite062009
protein binding 1.31870344025745 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle