YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: GPX2_MOUSE
Organism: Mus musculus
Length: 190 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GPX2_MOUSE.

Description E-value Query
Range
Subject
Range
GPX3 - glutathione peroxidase 3 (plasma)
1.293E7 [0..3] [187..35]
GPX3_RAT - Glutathione peroxidase 3 precursor - Rattus norvegicus (Rat)
1.293E7 [0..3] [187..35]
gi|32477575, gi|... - gi|32477575|ref|NP_870569.1| thioredoxin [Rhodopirellula baltica SH 1], gi|32448129|emb|CAD77646.1| ...
2.585E7 [0..15] [53..334]
gi|15899027, gi|... - gi|15899027|ref|NP_343632.1| peroxiredoxin [Sulfolobus solfataricus P2], gi|13815558|gb|AAK42422.1| ...
gi|25318992 - pir||G90395 hypothetical protein bcp-3 [imported] - Sulfolobus solfataricus
gi|241769027, gi... - gi|241769027|ref|ZP_04766450.1| alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal aller...
2.585E7 [0..9] [41..8]
GPX1_CHLRE - Glutathione peroxidase, mitochondrial precursor - Chlamydomonas reinhardtii
2.585E7 [0..4] [42..39]
gi|34556527 - gi|34556527|ref|NP_906342.1| putative lipoprotein thiredoxin [Wolinella succinogenes DSM 1740]
gi|34482241 - gi|34482241|emb|CAE09242.1| PUTATIVE LIPOPROTEIN THIREDOXIN [Wolinella succinogenes]
2.585E7 [0..11] [184..42]
RESA_OCEIH - Thiol-disulfide oxidoreductase resA OS=Oceanobacillus iheyensis GN=resA PE=3 SV=1
RESA_OCEIH - Thiol-disulfide oxidoreductase ResA OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC...
2.585E7 [0..9] [53..54]
GPX3_BOVIN - Glutathione peroxidase 3 precursor - Bos taurus (Bovine)
1.293E7 [0..2] [187..34]

Back

Predicted Domain #1
Region A:
Residues: [1-190]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYIAKSFYD LSAIGLDGEK IDFNTFRGRA VLIENVASLU GTTTRDYNQL NELQCRFPRR  60
   61 LVVLGFPCNQ FGHQENCQNE EILNSLKYVR PGGGYQPTFS LTQKCDVNGQ NEHPVFAYLK 120
  121 DKLPYPYDDP FSLMTDPKLI IWSPVRRSDV SWNFEKFLIG PEGEPFRRYS RSFQTINIEP 180
  181 DIKRLLKVAI 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.69897
Match: 1gp1A
Description: Glutathione peroxidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
selenium binding 3.88074839847028 bayes_pls_golite062009
antioxidant activity 3.8464796631544 bayes_pls_golite062009
glutathione binding 3.70571520983029 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.43831566988273 bayes_pls_golite062009
peroxidase activity 3.43831566988273 bayes_pls_golite062009
NADH dehydrogenase activity 3.34867897786732 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 3.27312030654855 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 3.14026319569721 bayes_pls_golite062009
glutathione transferase activity 3.10261229787796 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 2.66666794593609 bayes_pls_golite062009
glutathione peroxidase activity 2.56524997297011 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 2.5141654924344 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 2.23310780102446 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
transcription regulator activity 1.84647221968732 bayes_pls_golite062009
proteasome inhibitor activity 1.80247749812127 bayes_pls_golite062009
protein disulfide oxidoreductase activity 1.47769936616412 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
binding 1.25802922431343 bayes_pls_golite062009
protein binding 1.18479617596618 bayes_pls_golite062009
hydrolase activity 1.04103775676964 bayes_pls_golite062009
phospholipid-hydroperoxide glutathione peroxidase activity 0.874146425427531 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
signal transducer activity 0.588857285491299 bayes_pls_golite062009
molecular transducer activity 0.588857285491299 bayes_pls_golite062009
transferase activity 0.245320538630117 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle