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View Structure Prediction Details

Protein: ING5_MOUSE
Organism: Mus musculus
Length: 240 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ING5_MOUSE.

Description E-value Query
Range
Subject
Range
gi|53133760 - gi|53133760|emb|CAG32209.1| hypothetical protein [Gallus gallus]
205.0 [0..1] [240..1]
gi|187469549, gi... - gi|62655421|ref|XP_343635.2| PREDICTED: similar to inhibitor of growth family, member 5 [Rattus norv...
204.0 [0..1] [240..1]
gi|88959271 - gi|88959271|ref|XP_946119.1| PREDICTED: similar to inhibitor of growth family, member 5 [Homo sapien...
202.0 [0..12] [240..118]
gi|94966952, gi|... - gi|94966952|ref|NP_001035670.1| inhibitor of growth family, member 5 [Bos taurus], gi|83638568|gb|AA...
198.0 [0..1] [240..1]
gi|37362232, gi|... - gi|38016167|ref|NP_937854.1| inhibitor of growth family, member 5a [Danio rerio], gi|37362232|gb|AAQ...
198.0 [0..1] [239..1]
gi|37590948, gi|... - gi|45360937|ref|NP_988867.1| inhibitor of growth family, member 5 [Xenopus (Silurana) tropicalis], g...
196.0 [0..1] [238..1]
gi|148226875, gi... - gi|54311377|gb|AAH84763.1| LOC495304 protein [Xenopus laevis], gi|148226875|ref|NP_001088440.1| hypo...
196.0 [0..1] [238..1]

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Predicted Domain #1
Region A:
Residues: [1-165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATAMYLEHY LDSIENLPCE LQRNFQLMRE LDQRTEDKKA EIDILAAEYI STVKTLSSAQ  60
   61 RVEHLQKIQS AYSKCKEYSD DKVQLAMQTY EMVDKHIRRL DADLARFEAD LKDRMDGSDF 120
  121 ESTGARSLKK GRSQKEKRSS RGRGRRTSEE DTPKKKKHKS GSEFT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.04
Match: 1m1jC
Description: Fibrinogen C-terminal domains; Fibrinogen gamma chain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [166-240]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSILSVHPSD VLDMPVDPNE PTYCLCHQVS YGEMIGCDNP DCPIEWFHFA CVDLTTKPKG  60
   61 KWFCPRCVQE KRKKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.39794
Match: 1weuA
Description: Solution structure of PHD domain in ING1-like protein BAC25009
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
histone acetyltransferase activity 7.10262960897544 bayes_pls_golite062009
lysine N-acetyltransferase activity 7.10262960897544 bayes_pls_golite062009
N-acetyltransferase activity 5.0952093808777 bayes_pls_golite062009
4.93977737347339 bayes_pls_golite062009
4.75659254650148 bayes_pls_golite062009
N-acyltransferase activity 4.73470737654883 bayes_pls_golite062009
acetyltransferase activity 4.29938591960121 bayes_pls_golite062009
acyltransferase activity 3.59302841227183 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.54892905221507 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.34035867339622 bayes_pls_golite062009
histone binding 3.01402804224903 bayes_pls_golite062009
binding 2.93415748500038 bayes_pls_golite062009
transcription regulator activity 2.89424169822343 bayes_pls_golite062009
DNA binding 2.67786232715949 bayes_pls_golite062009
nucleic acid binding 2.6327300364647 bayes_pls_golite062009
protein binding 2.4739446713993 bayes_pls_golite062009
transcription repressor activity 2.13907615882531 bayes_pls_golite062009
transcription activator activity 2.06834170490665 bayes_pls_golite062009
protein deacetylase activity 1.85191754801422 bayes_pls_golite062009
histone deacetylase activity 1.81121374048292 bayes_pls_golite062009
methylated histone residue binding 1.80051107279585 bayes_pls_golite062009
transcription factor activity 1.62385700361588 bayes_pls_golite062009
sequence-specific DNA binding 1.17383679324331 bayes_pls_golite062009
deacetylase activity 0.912057424750107 bayes_pls_golite062009
histone methyltransferase activity 0.476506467104495 bayes_pls_golite062009
protein kinase activity 0.405766438875014 bayes_pls_golite062009
chromatin binding 0.39425178848458 bayes_pls_golite062009
nucleosome binding 0.252195940764881 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.14235705491362 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.0901653273812402 bayes_pls_golite062009
transcription factor binding 0.0538806851320555 bayes_pls_golite062009
histone methyltransferase activity (H3-K4 specific) 0.0490968711985191 bayes_pls_golite062009
kinase activity 0.00387875923819597 bayes_pls_golite062009

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