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View Structure Prediction Details

Protein: Fs-PA
Organism: Drosophila melanogaster
Length: 767 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Fs-PA.

Description E-value Query
Range
Subject
Range
gi|115764748, gi... - gi|115966263|ref|XP_001197817.1| PREDICTED: similar to receptor protein Notch1 [Strongylocentrotus p...
260.0 [0..5] [764..182]

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Predicted Domain #1
Region A:
Residues: [1-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHHHHQHQP TSSQNNLTFL KSNYKFKRRA MSMAIRALPA TTTPAEARRA EPSQNTDQLA  60
   61 ATMSKTSAAT ATQLARATSR ECRTILGLFI VSAWSALQEL ANCLRQDEDR YVGHGRDVNA 120
  121 SSDASDEVSM AREQQQHQRQ HSKHSASSSP AKSMRCTRAK AASASTGTAA ATATLGAAAA 180
  181 EGATSGHQLG GQPLMALLIG LLLLNFRLAA AGTCWQTHL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.69897
Match: 2p6aD
Description: No description for 2p6aD was found.

Predicted Domain #2
Region A:
Residues: [220-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSGKCGQVFS TDISRSECCG SSQSFSYTDR ELSSVEYFFA TAIGGGVECS PCMESCKGFK  60
   61 CGPNKKCVKR KGRPKCVCAP ECGAALRRRT HQQELELEQE PELEEEQQEM KPPRESRSLS 120
  121 SE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.39794
Match: 1jv2B
Description: Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [342-700]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTNFNLGLDG GQRQRADNQR KLQPRESKHR RLLIIDSSSR SSSNLPDQPT SGRRGRVEMT  60
   61 GYERRRHRNN HGKHLTRSMT TGANDSFPAD KTPAQSPAAD SILAQSRLAN LANANEPAND 120
  121 INRQSSTRVR HQHARRIEHA PNPDNGLRKR QHKQQQQHQH QHQDRMNTEA QSANTTVSGS 180
  181 GSGATNHRRI SQLQHGSETA ASSDLANTHD LAHLGGIYAP LPPQHSNPVC GTDGRTYNTE 240
  241 CQLRKRACRT NNAQLEVAYR GHCKNSCSGV HCLNGLTCVE DQYLMPHCIA CRIECPWDNL 300
  301 DVDSSGYDER QAVCGVDGKT YRSACDINRM ICKIGRSIAV AYPGPCRAGR VSCADIKCG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1n7dA
Description: Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.286076792172079 bayes_pls_golite062009
protein binding 0.14494900666454 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [701-767]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKDNCLVDLQ TRQPRCVTCR YKCPRKQQRP VHKICGYNNQ TYNSWCEMHK HSCESRYFIG  60
   61 VKSQGSC

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.02
Match: 2p6aD
Description: No description for 2p6aD was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle