YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Nup133-PA
Organism: Drosophila melanogaster
Length: 1200 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Nup133-PA.

Description E-value Query
Range
Subject
Range
NUP133 - nucleoporin 133kDa
gi|157928803, gi... - gi|157928803|gb|ABW03687.1| nucleoporin 133kDa [synthetic construct], gi|123995185|gb|ABM85194.1| nu...
1226.0 [0..8] [1187..3]

Back

Predicted Domain #1
Region A:
Residues: [1-536]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERNLQKQLY GISRESSPGA RRYSMPAASA DSTRKSIFGG SASCAQMSGS LKRTALTNSR  60
   61 LSLSVRSTQS IAGIRSDYNS VESFGCPLPV VVNEALTFAG PGAGTVTAKV TQNGWAWVVQ 120
  121 GRRLLIWQYK DTAKSGSPPR VGKLARRGGG LAQCRELTLP YSDLGHKSDL ISVFQTEGQQ 180
  181 MASCIAVSAT GEVRYWSSIA HDGNSVDLSI LTGQEFVQLL SLPTQQGYLA VTTTCNLVFL 240
  241 RVGLTNGRYT LHHKTIKPAT SFLGGFGKKF ASILIGMNTG ADKDQTLVGM CCESNLESGE 300
  301 TIVAVLSDRA IQRWSLSNNG NTENLLYEDA DMLRRIREEF ITNFWKFRLP ADSLEIDLHL 360
  361 LDFHVVKNKA YILAGAVNAA HAPQMCYALV TGTAQAERML LESFTPLNMN KFFSAKTEED 420
  421 CLSVRFVVGS SHIYLYTSKV VYPLHLTNSV PTAELEAEKI EFHQHDDRIL SAVICSQLPL 480
  481 FFSRTHGLVS ITPGDFDGTE MMNMSSCNTP DLYAPNSCNA SFAVADHSAL TNSTNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 121.0
Match: 1xksA
Description: The crystal structure of the N-terminal domain of Nup133 reveals a beta-propeller fold common to several nucleoporins
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleocytoplasmic transporter activity 7.36869426424539 bayes_pls_golite062009
transporter activity 2.55928656852707 bayes_pls_golite062009
binding 1.5683135853172 bayes_pls_golite062009
protein binding 0.571876690720183 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [537-671]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LHLFELDPDE MYNELSDEVG QLKAAFLYHM KRNSNMVKTI VDELLRNVTA ADPSGAPMDA  60
   61 YKLDRIVITI AEDLAEDIPI ADPRWEEALA DQEMNRHAIG SSRSMQIINQ LRDKIIAFQH 120
  121 FITFLHSSLV WDKLN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [672-862]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VIPCGSHSLK PTGCILADIS EKIVAAMALR SIQTKLPKLI EEAIDATVAL WHEEPQGSLT  60
   61 YQDIFYVKLS RFQNVFEALA DIADDRIAAQ NQTTISVAHF VNEINSIVLD VLGQVFKYRK 120
  121 QHASSFRLSH EKLPSYENLP WTAMAGSAGV RDTLTRLIDI SVRYGSHCVS ETELKQQLYQ 180
  181 QIFELIDLVL D

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [863-938]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRKTYLKSVR DTEKFNVLQQ QFEAQRRELI SVLIKDRQYE YAAKIAEKYL DFQSLVLICD  60
   61 ETQDKERLED YTRKYE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [939-1101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYDFSQFAIN WHLRQNRHGE VFERFKGNQT ALAQFMRDHP SLGWIQLIFN GDFERAAKVL  60
   61 YELAQCETEF VARKKSMLSL AKLAAFAAAE SDLTAQVEKI NADLTLVEYQ SQLGHDVLES 120
  121 FGFDPAEQKV LKAEEIISLY IAEENETASE TEFRKALELL SYV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1102-1200]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQPYDMRHKI WCAAIKRDNW TDYDPNNAVH YMQKLLFYKI IEISQLMGND SENVLPPMED  60
   61 FLESVELGDL PQQKPFQYLL KLTYEYVADM FKQPDDMEL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle