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View Structure Prediction Details

Protein: CG9059-PA
Organism: Drosophila melanogaster
Length: 1077 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG9059-PA.

Description E-value Query
Range
Subject
Range
gi|7293308, gi|2... - gi|7293308|gb|AAF48688.1| CG9059-PB, isoform B [Drosophila melanogaster], gi|24642699|ref|NP_573185....
526.0 [0..33] [1077..2]

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Predicted Domain #1
Region A:
Residues: [1-83]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEIQKPHSA LKRPSLKRET VVVNNSAPTI KKVTLVPKDE ELVAISPERR NWRGIFIALL  60
   61 VIAAVFSLII FSIFLLSPED EGL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [84-145]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RIRGRRMLPS DILGRSLQWK PFNGTWSNGR ELIYRDPTGG LSILNMADLT TRILMTNSTF  60
   61 RQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.154902
Match: 2g9aA
Description: No description for 2g9aA was found.

Predicted Domain #3
Region A:
Residues: [146-969]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNAESFLVAP DQKYVLLQSD SNAEGSRHHV YEVQTANTFP LGPTENIAEA PRLQHVVWAP  60
   61 ANPPPPLGAP PPSGASGASG ASGASTTTMA PLPSGSIILN SLAGAANGPA SAGASGSSAP 120
  121 NPNGKAGGYN LNQAIAFVHH NDIYYKPKVQ GELVCRITQT GSGSLEGEST GVVFNGVPDW 180
  181 MYENVPELES RRSSMEFSPD GLFLAFLSYN DSEVNEYKYT WMGDDIKYPA VMSQRYPKTG 240
  241 SRNPNVTVNV VNLSVIKYIF PTQIKLPSEL SNGSYVGGLT WASSTDLSVT VTNREQTKAT 300
  301 TVLCRAPHFH CQAVHTEVTI NDGWVLPSER PIFSVRNQGH NRLGKMVQNA EEIQAESQNV 360
  361 NVTDGQTHTT HEISNGGYLL KRLPVRDGEH GHYRHVVFIS SLDRRPVPLT MGRFEVTEIV 420
  421 GWDEPHEIVY FMAAPEKRPG ERHLYKISLK LNVTESNRTY ITSTSPTCLT CDNTESTYRL 480
  481 HRARISQRGD RWEDIVARLE PDDCLYDIPK NCLFNRVQFS QDYSYYVQEC LGPEAPSVYL 540
  541 VETASNDKIY VLNAGDVLRH RLSQLAIPQS RTFSVEIRHG FHAQVRLFLP PGMREEEDVA 600
  601 FPLVLHVDAS PGSQLVTERF HVDWNWYLAS QRSFIVAQID GRGSGFQGEL LRTQVHGKLG 660
  661 TVEVEDQLGV LTYLRDNLKF IDPLRICAFG WGYGGYASSM MLIDDSQQVL QCAVAINPIV 720
  721 NFGFHYSFFT ERYIPLKGDY LRALQEADLT MKAGNIKGRN LMLMHGTADT LVHQEHTLML 780
  781 VRALVEQQVK FRHQVYPDED HAIARSLSHV YKTMEWYFDE CFGP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 83.69897
Match: 1orvA
Description: Dipeptidyl peptidase IV/CD26, N-terminal domain; Dipeptidyl peptidase IV/CD26, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 4.09944423676394 bayes_pls_golite062009
peptidase activity 2.49064988313037 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.10044305272656 bayes_pls_golite062009
catalytic activity 1.39629727416851 bayes_pls_golite062009
palmitoyl-(protein) hydrolase activity 1.01438408843885 bayes_pls_golite062009
binding 0.549512873906854 bayes_pls_golite062009
heparin binding 0.437236652275566 bayes_pls_golite062009
endopeptidase activity 0.43631945855397 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.282381128231187 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [970-1077]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDDNEWDPTG LFLSDIDIGP ATDAHPDADA AGDSAGSNLS TLLTATTTSA SLSALDELDN  60
   61 RLQALDLITS STATTLSKVA GKLCNYSSKR RLHQSEAVLA QKSRILQH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1b41A
Description: Acetylcholinesterase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle