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View Structure Prediction Details

Protein: FBpp0301193, AP-...
Organism: Drosophila melanogaster
Length: 963 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0301193, AP-....

Description E-value Query
Range
Subject
Range
AP-1gamma-PB - The gene AP-1Ã?ŽÃ?³ is referred to in FlyBase by the symbol Dmel\AP-1Ã?ŽÃ?³ (CG9113, FBg...
620.0 [0..2] [963..15]

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Predicted Domain #1
Region A:
Residues: [1-675]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSEHGFNPA FNMATIRQAF TEAVERVRMP TPTRLRDLIR QIRAARTAAE ERAVVNKECA  60
   61 YIRSTFREED SVWRCRNIAK LLYIHMLGYP AHFGQLECLK LTASTRFTDK RIGYLGAMLL 120
  121 LDERQDVHLL ITNCLKNDLN SSTQFVVGLA LCTLGAIASP EMARDLASEV ERLMKSPNTY 180
  181 IRKKATLCAF RVIRRVPELM EIFLPATRSL LSEKNHGILI TGVTLITEMC ENSSDTLMHF 240
  241 KKIVPNLVRI LKNLILGGYS PEHDVSGVSD PFLQVKILRL LRILGHNDPD ASEAMNDILA 300
  301 QVATNTETSK NVGNTILYET VLSIMDIRSE GGLRVLAVNI LGRFLLNSDK NIRYVALNTL 360
  361 LRTVHADTSA VQRHRTTILE CLKDPDVSIR RRAMELSFAL INAQNIRTMT KELLLFLEKA 420
  421 DAEFKAQCSS GMILAAERYS PTTRWHLDTQ LSVLIAAGNY VRDDVVSSTI QLVSSSPVPE 480
  481 QTYITNRFWE SLQVANHCED KQPLLQVAVW AIGEYGDLFM YGANEDEFER PTESDLIAVY 540
  541 YKFLTSAQVS TTSKQYALVS LAKLSTRLQQ CVEEIQALIT SFGSHLNVDL QQRGVEFTQL 600
  601 FGHYKHLRPP LLEKMPAMQI SRISSQNGES GGGSFDDNSP DVIENGVEGG GGGGHSLIES 660
  661 NMNTLGDNTN ILLDL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 150.0
Match: 1w63A
Description: AP1 clathrin adaptor core
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [676-774]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGSTDLSAGG AGDLVAATDL SNAVHKKNSR NANDVVAPVS NNQDLLDLLD LDLSAPSSTT  60
   61 TGAPAGGGGG GGIVALVGDN NQSSAANMNN MLGGLDLGG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [775-963]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FGSGLDSSAS IPTNGNDLAS MLGGLGAPPA ASPSLAASAP VGNLIDGHAG SLLADLNPTA  60
   61 ASNNVVVPPQ GPRLTALDKD GLLVQLVSVR GSDCMRIYMT TTNNSDNTLD QYLLQAAVQR 120
  121 SFQLQMLTPS GSVLPPGGVI TQEMRVVATS NATLRMRLRI QYVLDGQQQV EQTEVSGFPE 180
  181 QQPAPAAAE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.221849
Match: 1iu1A
Description: Gamma1-adaptin domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.73706375360191 bayes_pls_golite062009
protein binding 1.07977592306595 bayes_pls_golite062009
transporter activity 0.169557557237959 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle