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View Structure Prediction Details

Protein: fd3F-PB
Organism: Drosophila melanogaster
Length: 360 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fd3F-PB.

Description E-value Query
Range
Subject
Range
gi|76654354 - gi|76654354|ref|XP_590057.2| PREDICTED: similar to forkhead box K1 [Bos taurus]
169.0 [0..4] [335..368]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWLKSKTNHR KTSRPKKPPF TYTELIEYAL EDKGELTVSG IYQWISDRFP YYKSNDDRWK  60
   61 NSVRHNLSIN PHFRKGVKAP QGAGHLWAIS SGDSAENVLA WEHKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.154902
Match: 1d5vA
Description: Adipocyte-transcription factor FREAC-11 (s12, fkh-14)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.55329976718261 bayes_pls_golite062009
DNA binding 5.08959163553491 bayes_pls_golite062009
nucleic acid binding 4.99681957904233 bayes_pls_golite062009
transcription factor activity 4.33152142980289 bayes_pls_golite062009
transcription activator activity 3.70589483230587 bayes_pls_golite062009
sequence-specific DNA binding 3.58179858678904 bayes_pls_golite062009
binding 3.52874320222492 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.60738445921725 bayes_pls_golite062009
transcription repressor activity 2.22485867684613 bayes_pls_golite062009
protein binding 1.80415286835431 bayes_pls_golite062009
transcription factor binding 0.85714789329232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.66743181561551 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.23177057841536 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [106-214]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRLDLFFKME SINRERIQQH QQQQQLQQHQ QQHQQHSPQQ KQHSAAQQQH MPQASSCMYD  60
   61 EAAVAVATLT QEMMQTNSGG GSTETSQQQQ QQQQHHHHHS HQNHQNHNQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [215-360]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HHQRLLPFND LLSDDELRKT AGQILNGIHR EVEVQSVNSI ISTYHDVLLD NDYLNPIHKD  60
   61 VVVTESVLRQ QHGTNLGGGN NNQNNQMGGN SHMGGGNSQY YITEIDPMEL GIQMSHQVEP 120
  121 SEEEVLFSDE FNLNYFGYNP GSDIVA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle