YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: dwg-PA
Organism: Drosophila melanogaster
Length: 592 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dwg-PA.

Description E-value Query
Range
Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
664.0 [0..146] [592..2411]

Back

Predicted Domain #1
Region A:
Residues: [1-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMNSKIAEVV VLNCRTCTRA CKLHKPLQEE IDLGSEGSTT LASMLNYCTG LSFEPQDGAA  60
   61 MPQHICLHCL QLLEQAFNFK RMVIDSDELL RLG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.0
Match: 1pzwA
Description: Crystal structure of the zinc finger associated domain of the Drosophila transcription factor Grauzone
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.00967542385368 bayes_pls_golite062009
DNA binding 3.60745514727532 bayes_pls_golite062009
nucleic acid binding 3.47256374293954 bayes_pls_golite062009
binding 2.96409924710655 bayes_pls_golite062009
transcription factor activity 2.90769972671972 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.40923942043513 bayes_pls_golite062009
transcription repressor activity 1.88834375049208 bayes_pls_golite062009
sequence-specific DNA binding 1.62841402245495 bayes_pls_golite062009
transcription activator activity 1.62405765585032 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.49515149729803 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.46067968492906 bayes_pls_golite062009
protein binding 1.39455913713025 bayes_pls_golite062009
transcription factor binding 1.38523780690867 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.26452462867497 bayes_pls_golite062009
structural constituent of ribosome 1.14370842685155 bayes_pls_golite062009
structural molecule activity 1.03433454627943 bayes_pls_golite062009
transcription cofactor activity 0.58115018700114 bayes_pls_golite062009
catalytic activity 0.101795606736461 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [94-157]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDEARCSSFH ESQTHSPNQS QQHDQQQQAF DSTEEYVMIE MLNEEQENVA NLDEELAEED  60
   61 RRIF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.522879
Match: 1v65A
Description: Solution structure of the Kruppel-associated box (KRAB) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 2.36376512665406 bayes_pls_golite062009
DNA binding 2.2458683155586 bayes_pls_golite062009
binding 2.05464920186799 bayes_pls_golite062009
protein binding 0.476896736636797 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [158-364]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AMTVDEEEEF LTEEVDQDDE LSEEEHQLAQ SGDQQEEHIT MESVHEFQPA EVEYVTIKNE  60
   61 FETIVTEEDE FEVMNDSGAH DAILDCQMIV IPAEGAIDEV IGEETLELEG DGREEHLLPE 120
  121 AEDVCEDEDF LEESLDSAPP TAGEALPYVC TVCQKAFRQQ CRLNQHMRSH VDEKQYECEE 180
  181 CGKRLKHLRN YKEHMLTHTN VKPHQCS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 7.6
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #4
Region A:
Residues: [365-592]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ICGRFYRTTS SLAVHKRTHA EKKPYNCDQC GRGYAAFDHL RRHKLTHTGE RPYACDLCDK  60
   61 AYYDSSSLRQ HKISHTGKKA FTCEICGVGL SQKSGYKKHM MVHSGVKAHK CDVCGHAFTF 120
  121 TSNLNAHVRL HSGEKPFKCE VCVKAFPTKK RLASHMRVHN KESPVTATVA VQSINPPSRQ 180
  181 AGAEGATGGG ATGGSPTGGG ATGGSATNLH ITEVHEQPVS TSKVVMVL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.69897
Match: 2i13A
Description: No description for 2i13A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle