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View Structure Prediction Details

Protein: gi|84796203, gi|...
Organism: Drosophila melanogaster
Length: 1403 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|84796203, gi|....

Description E-value Query
Range
Subject
Range
FBpp0088624, FBp... - The gene La related protein is referred to in FlyBase by the symbol Dmel\larp (CG42551, FBgn0260724)...
646.0 [0..439] [1403..1]

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Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAKQSGSPK AGTSPLDKRV LQPKAQQQQQ QTKQTASQNN NAQNTASNKK TQQQQQPQQG  60
   61 ATTTTQTTTA AAAAATAAAA ATAATTSAAA ATSSAAAVPA ATTETATTTT VDASQADALA 120
  121 KV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [123-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVKDKKKVNQ KASDFSNVGD WPTLIGGTSG SGKATSNEPK RNPTKKQQSA KTAAAVAASS  60
   61 NTTSSEVATE SNVAGTTSSS NSNPSSSTTT TNTTTNSQAT TAPVASTSHD AKAQRDAEPA 120
  121 ANSAAGTTGT AAGPALTKKI PKHKWRPLPI DLAKSSRPKP IGGRPNRRFS DDI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [296-452]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADQRRPPRVY HDRQPGAGGA GVESRHPHAG RHPYGSRPAT ATSERVDSWR SSSSTTTAAF  60
   61 DEQRSGAAGG AGAAGTGVGS ATRGPRRYRT PYRGGRQGRG GFSRQGPGRP TYRIPRHLLA 120
  121 SGEYANYLPA DAAGADSQSS YVLMGTHYFG NVPAAYI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [453-584]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELDANSIKEA IKKQVEYYFS VDNLTGDFFL RRKMDPEGYI PVTLIASFHR VLALTTDVAV  60
   61 IVNAIKESDK LELFEGYKVR TKTTPTTWPI TEVPEVNEGE PKAIGTLEQE QLEQNDGQEK 120
  121 LEEQTEADSP PP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.17
Match: 2cqkA
Description: Solution structure of the La domain of c-Mpl binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.683379929086364 bayes_pls_golite062009
transcription regulator activity 0.16959343932447 bayes_pls_golite062009
nucleic acid binding 0.0949481158963694 bayes_pls_golite062009
DNA binding 0.00746597740509714 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [585-693]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILTSAMATKP LNSIPPPPMP RNPQNLVPKM LQDKQQSRSS TIAALNSVNA ISALTQQVEG  60
   61 GAAELAGHLS GLAESVKPKS TSTPDKRNAA SAGNGAGSAA ALVAEPEGI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [694-830]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WKEVKRRSKT NAIKENATTP PQQQQPPLSQ TLNNNNDNVK TNNTSSKSKS SSNNAPSNAS  60
   61 SSATVCVTTN NASSATKATT KTTTTSTATT TTNNNIKSGN AAYSKTHSKS SSKTAAPPSA 120
  121 QCHAEKEELD FQFDEEL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [831-1061]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPLPPGTGR INNFTENFSD DDESDYEFAD RDINKLLIVA QVGRAPKHEG YDRTADFTSR  60
   61 TKITQDLENI INDGLVNYEE DLWTTTNVVA DYKTVNVISQ ADFEKLAGGR NKSVLPPQVV 120
  121 PPPPPFEEDL DETLVGDTTL NSTLNNTLKS RRARFYAAPN SHSIDPRTPR KRKLRHTANP 180
  181 PVEAHVGWLL DTVEHRPRTT SMGSSAGTSP TASSYGSFGS SVPQSLPVFQ H

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1062-1223]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSHALLKENN FTQQAYHKYH SRCLKERRRL GYGQSQEMNT LYRFWSFFLR ENFNKSMYNE  60
   61 FRSLALEDAG NGFRYGLECL FRFFSYGLEK KFRPNIYQDF QDETIADYET GQLYGLEKFW 120
  121 AFLKYYKNGE KLEVQPKLAE YLKSFKNIED FRVVEPEINE ML

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1224-1403]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGVGSLNPGR QLNRHRSVSE SDGTAVIAAG GRRLNTTITN RSDYVGRLLQ QQHQQQQQQQ  60
   61 HHQYQQGYGG YNQQQNRRRT GSFGSTTVRI RSGSLGNKPQ VANRNQGSQH ELRRGGSNSG 120
  121 LAPHKRQQQQ KPKPGAGSQT GSTRATTSAA ATATTAASAA TSTAATPAVT VSSGSSSSKK 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle