YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|119605155, gi...
Organism:	Homo sapiens
Length:	257 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|119605155, gi....

Description	E-value	Query Range	Subject Range
gi\|71675440, gi\|... - gi\|71675440\|ref\|ZP_00673185.1\| TPR repeat:Sel1-like repeat [Trichodesmium erythraeum IMS101], gi\|716...	5.0E-44	[17..256]	[1062..1291]
gi\|160879503, gi... - gi\|160879503\|ref\|YP_001558471.1\| beta-lactamase domain-containing protein [Clostridium phytofermenta...	2.0E-41	[15..256]	[9..240]
gi\|76659287 - gi\|76659287\|ref\|XP_885188.1\| PREDICTED: similar to O-linked GlcNAc transferase isoform 1 isoform 13 ...	3.0E-41	[18..256]	[68..296]
gi\|18250916, gi\|... - gi\|6911265\|gb\|AAF31458.1\| HRNT1 [Homo sapiens], gi\|2266994\|gb\|AAB63466.1\| O-linked GlcNAc transferas...	1.0E-40	[18..256]	[67..295]
gi\|72002782, gi\|... - gi\|72382932\|ref\|YP_292287.1\| TPR repeat-containing protein [Prochlorococcus marinus str. NATL2A], gi...	9.0E-40	[17..252]	[115..336]
gi\|40063716 - gi\|40063716\|gb\|AAR38497.1\| TPR repeat protein [uncultured marine bacterium 583]	1.0E-39	[19..256]	[43..271]
gi\|46119251, gi\|... - gi\|67923685\|ref\|ZP_00517153.1\| TPR repeat:TPR repeat [Crocosphaera watsonii WH 8501], gi\|67854485\|gb...	1.0E-39	[18..256]	[278..506]

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Predicted Domain #1

Region A:
Residues: [1-257]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPPAPGPAS GGSGEVDELF DVKNAFYIGS YQQCINEAQR VKLSSPERDV ERDVFLYRAY  60
   61 LAQRKFGVVL DEIKPSSAPE LQAVRMFADY LAHESRSTAM TVQILLKLDR LDLARKELKR 120
  121 MQDLDEDATL TQLATAWVSL ATGGEKLQDA YYIFQEMADK CSPTLLLLNG QAACHMAQGR 180
  181 WEAAEGLLQE ALDKDSGYPE TLVNLIVLSQ HLGKPPEVTN RYLSQLKDAH RSHPFIKEYQ 240
  241 AKENDFDRLV LQYAPSA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.522879
Match:	1w3bA
Description:	The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.14253214573541	bayes_pls_golite062009
protein binding	1.83529176977066	bayes_pls_golite062009
signal sequence binding	0.49295886046194	bayes_pls_golite062009
syntaxin binding	0.0598606763736398	bayes_pls_golite062009
peroxisome targeting sequence binding	0.0468412220974996	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: