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View Structure Prediction Details

Protein: gi|40018629
Organism: Homo sapiens
Length: 1173 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|40018629.

Description E-value Query
Range
Subject
Range
gi|114646636 - gi|114646636|ref|XP_522571.2| PREDICTED: similar to KIAA1033 protein [Pan troglodytes]
1905.0 [0..1] [1173..67]
gi|5689403 - gi|5689403|dbj|BAA82985.1| KIAA1033 protein [Homo sapiens]
1902.0 [0..1] [1173..24]
gi|73969965 - gi|73969965|ref|XP_531762.2| PREDICTED: similar to CG13957-PA [Canis familiaris]
1890.0 [0..4] [1173..139]
gi|38090591, gi|... - gi|94389530|ref|XP_995118.1| PREDICTED: similar to CG13957-PA [Mus musculus], gi|94388794|ref|XP_992...
1874.0 [0..1] [1173..91]
gi|62651891, gi|... - gi|62651891|ref|XP_235003.3| PREDICTED: similar to CG13957-PA [Rattus norvegicus], gi|109481736|ref|...
1844.0 [0..1] [1173..1]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVETLSPDW EFDRVDDGSQ KIHAEVQLKN YGKFLEEYTS QLRRIEDALD DSIGDVWDFN  60
   61 LDPIALKLLP YEQSSLLELI KTENKVLNKV ITVYAALCCE IKKLKYEAET KFYNGLLFYG 120
  121 EGATDASMVE GDCQIQMGR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [140-233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FISFLQELSC FVTRCYEVVM NVVHQLAALY ISNKIAPKII ETTGVHFQTM YEHLGELLTV  60
   61 LLTLDEIIDN HITLKDHWTM YKRLLKSVHH NPSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.970 a.47.1 STAT

Predicted Domain #3
Region A:
Residues: [234-312]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FGIQEEKLKP FEKFLLKLEG QLLDGMIFQA CIEQQFDSLN GGVSVSKNST FAEEFAHSIR  60
   61 SIFANVEAKL GEPSEIDQR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.846 a.144.1 PABC (PABP) domain

Predicted Domain #4
Region A:
Residues: [313-423]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKYVGICGLF VLHFQIFRTI DKKFYKSLLD ICKKVPAITL TANIIWFPDN FLIQKIPAAA  60
   61 KLLDRKSLQA IKIHRDTFLQ QKAQSLTKDV QSYYVFVSSW MMKMESILSK E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [424-577]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRMDKFAEDL TNRCNVFIQG FLYAYSISTI IKTTMNLYMS MQKPMTKTSV KALCRLVELL  60
   61 KAIEHMFYRR SMVVADSVSH ITQHLQHQAL HSISVAKKRV ISDKKYSEQR LDVLSALVLA 120
  121 ENTLNGPSTK QRRLIVSLAL SVGTQMKTFK DEEL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [578-811]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPLQVVMKKL DLISELRERV QTQCDCCFLY WHRAVFPIYL DDVYENAVDA ARLHYMFSAL  60
   61 RDCVPAMMHA RHLESYEILL DCYDKEIMEI LNEHLLDKLC KEIEKDLRLS VHTHLKLDDR 120
  121 NPFKVGMKDL ALFFSLNPIR FFNRFIDIRA YVTHYLDKTF YNLTTVALHD WATYSEMRNL 180
  181 ATQRYGLVMT EAHLPSQTLE QGLDVLEIMR NIHIFVSRYL YNLNNQIFIE RTSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [812-903]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKHLNTINIR HIANSIRTHG TGIMNTTVNF TYQFLKKKFY IFSQFMYDEH IKSRLIKDIR  60
   61 FFREIKDQND HKYPFDRAEK FNRGIRKLGV TP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.880 a.7.6 Ribosomal protein S20

Predicted Domain #8
Region A:
Residues: [904-1009]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGQSYLDQFR QLISQIGNAM GYVRMIRSGG LHCSSNAIRF VPDLEDIVNF EELVKEEGLA  60
   61 EETLKAARHL DSVLSDHTRN SAEGTEYFKM LVDVFAPEFR RPKNIH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.854 a.7.5 Tubulin chaperone cofactor A

Predicted Domain #9
Region A:
Residues: [1010-1173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRNFYIIVPP LTLNFVEHSI SCKEKLNKKN KIGAAFTDDG FAMGVAYILK LLDQYREFDS  60
   61 LHWFQSVREK YLKEIRAVAK QQNVQSASQD EKLLQTMNLT QKRLDVYLQE FELLYFSLSS 120
  121 ARIFFRADKT AAEENQEKKE KEEETKTSNG DLSDSTVSAD PVVK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle