YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|40018629
Organism: Homo sapiens
Length: 1173 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|40018629.

Description E-value Query
Range
Subject
Range
gi|114646636 - gi|114646636|ref|XP_522571.2| PREDICTED: similar to KIAA1033 protein [Pan troglodytes]
1905.0 [0..1] [1173..67]
gi|5689403 - gi|5689403|dbj|BAA82985.1| KIAA1033 protein [Homo sapiens]
1902.0 [0..1] [1173..24]
gi|73969965 - gi|73969965|ref|XP_531762.2| PREDICTED: similar to CG13957-PA [Canis familiaris]
1890.0 [0..4] [1173..139]
gi|38090591, gi|... - gi|94389530|ref|XP_995118.1| PREDICTED: similar to CG13957-PA [Mus musculus], gi|94388794|ref|XP_992...
1874.0 [0..1] [1173..91]
gi|62651891, gi|... - gi|62651891|ref|XP_235003.3| PREDICTED: similar to CG13957-PA [Rattus norvegicus], gi|109481736|ref|...
1844.0 [0..1] [1173..1]

Back

Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVETLSPDW EFDRVDDGSQ KIHAEVQLKN YGKFLEEYTS QLRRIEDALD DSIGDVWDFN  60
   61 LDPIALKLLP YEQSSLLELI KTENKVLNKV ITVYAALCCE IKKLKYEAET KFYNGLLFYG 120
  121 EGATDASMVE GDCQIQMGR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.717 a.24.1 Apolipoprotein
View Download 0.717 a.24.1 Apolipoprotein
View Download 0.697 a.24.9 alpha-catenin/vinculin
View Download 0.690 a.24.9 alpha-catenin/vinculin
View Download 0.631 a.246.1 Description not found.
View Download 0.628 a.281.1 Description not found.
View Download 0.625 a.25.1 Ferritin-like
View Download 0.620 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.567 a.7.1 Spectrin repeat
View Download 0.559 a.7.7 BAG domain
View Download 0.290 d.38.1 Thioesterase/thiol ester dehydrase-isomerase
View Download 0.275 d.110.4 SNARE-like
View Download 0.263 a.1.1 Globin-like
View Download 0.238 d.110.4 SNARE-like
View Download 0.232 d.227.1 OsmC-like

Predicted Domain #2
Region A:
Residues: [140-233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FISFLQELSC FVTRCYEVVM NVVHQLAALY ISNKIAPKII ETTGVHFQTM YEHLGELLTV  60
   61 LLTLDEIIDN HITLKDHWTM YKRLLKSVHH NPSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.970 a.47.1 STAT
View Download 0.945 a.47.1 STAT
View Download 0.944 a.24.9 alpha-catenin/vinculin
View Download 0.933 a.47.2 t-snare proteins
View Download 0.933 a.47.2 t-snare proteins
View Download 0.928 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.928 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.928 a.24.3 Cytochromes
View Download 0.918 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.901 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.814 a.7.8 GAT domain
View Download 0.660 a.7.8 GAT domain
View Download 0.619 g.39.1 Glucocorticoid receptor-like (DNA-binding domain)
View Download 0.594 a.16.1 S15/NS1 RNA-binding domain
View Download 0.548 a.7.8 GAT domain

Predicted Domain #3
Region A:
Residues: [234-312]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FGIQEEKLKP FEKFLLKLEG QLLDGMIFQA CIEQQFDSLN GGVSVSKNST FAEEFAHSIR  60
   61 SIFANVEAKL GEPSEIDQR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.846 a.144.1 PABC (PABP) domain
View Download 0.846 a.144.1 PABC (PABP) domain
View Download 0.806 a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.788 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.730 f.14.1 Voltage-gated potassium channels
View Download 0.730 f.14.1 Voltage-gated potassium channels
View Download 0.703 a.5.3 N-terminal domain of phosphatidylinositol transfer protein sec14p
View Download 0.697 a.144.1 PABC (PABP) domain
View Download 0.365 d.58.7 RNA-binding domain, RBD
View Download 0.296 a.74.1 Cyclin-like
View Download 0.290 a.159.5 Description not found.
View Download 0.288 a.1.1 Globin-like
View Download 0.284 a.4.1 Homeodomain-like

Predicted Domain #4
Region A:
Residues: [313-423]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKYVGICGLF VLHFQIFRTI DKKFYKSLLD ICKKVPAITL TANIIWFPDN FLIQKIPAAA  60
   61 KLLDRKSLQA IKIHRDTFLQ QKAQSLTKDV QSYYVFVSSW MMKMESILSK E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.541 a.39.2 Insect pheromon/odorant-binding proteins
View Download 0.540 c.23.5 Flavoproteins
View Download 0.538 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.538 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.523 a.29.13 Description not found.
View Download 0.520 a.29.16 Description not found.
View Download 0.510 a.26.1 4-helical cytokines
View Download 0.429 a.25.1 Ferritin-like
View Download 0.390 a.25.1 Ferritin-like
View Download 0.386 a.2.5 Prefoldin
View Download 0.317 c.51.2 TolB, N-terminal domain
View Download 0.281 d.110.4 SNARE-like
View Download 0.260 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.219 c.44.1 Phosphotyrosine protein phosphatases I
View Download 0.215 d.360.1 Description not found.

Predicted Domain #5
Region A:
Residues: [424-577]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRMDKFAEDL TNRCNVFIQG FLYAYSISTI IKTTMNLYMS MQKPMTKTSV KALCRLVELL  60
   61 KAIEHMFYRR SMVVADSVSH ITQHLQHQAL HSISVAKKRV ISDKKYSEQR LDVLSALVLA 120
  121 ENTLNGPSTK QRRLIVSLAL SVGTQMKTFK DEEL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [578-811]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPLQVVMKKL DLISELRERV QTQCDCCFLY WHRAVFPIYL DDVYENAVDA ARLHYMFSAL  60
   61 RDCVPAMMHA RHLESYEILL DCYDKEIMEI LNEHLLDKLC KEIEKDLRLS VHTHLKLDDR 120
  121 NPFKVGMKDL ALFFSLNPIR FFNRFIDIRA YVTHYLDKTF YNLTTVALHD WATYSEMRNL 180
  181 ATQRYGLVMT EAHLPSQTLE QGLDVLEIMR NIHIFVSRYL YNLNNQIFIE RTSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [812-903]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKHLNTINIR HIANSIRTHG TGIMNTTVNF TYQFLKKKFY IFSQFMYDEH IKSRLIKDIR  60
   61 FFREIKDQND HKYPFDRAEK FNRGIRKLGV TP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.880 a.7.6 Ribosomal protein S20
View Download 0.842 a.24.4 Hemerythrin
View Download 0.821 a.24.28 Description not found.
View Download 0.812 a.29.10 Description not found.
View Download 0.805 a.24.9 alpha-catenin/vinculin
View Download 0.801 a.46.1 Methionine synthase domain
View Download 0.780 a.133.1 Phospholipase A2, PLA2
View Download 0.777 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.773 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)

Predicted Domain #8
Region A:
Residues: [904-1009]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGQSYLDQFR QLISQIGNAM GYVRMIRSGG LHCSSNAIRF VPDLEDIVNF EELVKEEGLA  60
   61 EETLKAARHL DSVLSDHTRN SAEGTEYFKM LVDVFAPEFR RPKNIH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.854 a.7.5 Tubulin chaperone cofactor A
View Download 0.854 a.7.5 Tubulin chaperone cofactor A
View Download 0.802 a.24.17 Group V grass pollen allergen
View Download 0.802 a.24.17 Group V grass pollen allergen
View Download 0.797 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.680 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.680 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.622 a.7.1 Spectrin repeat
View Download 0.500 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.291 d.58.4 Dimeric alpha+beta barrel
View Download 0.273 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.219 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.215 a.16.1 S15/NS1 RNA-binding domain

Predicted Domain #9
Region A:
Residues: [1010-1173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRNFYIIVPP LTLNFVEHSI SCKEKLNKKN KIGAAFTDDG FAMGVAYILK LLDQYREFDS  60
   61 LHWFQSVREK YLKEIRAVAK QQNVQSASQD EKLLQTMNLT QKRLDVYLQE FELLYFSLSS 120
  121 ARIFFRADKT AAEENQEKKE KEEETKTSNG DLSDSTVSAD PVVK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle