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View Structure Prediction Details

Protein: CDYL
Organism: Homo sapiens
Length: 598 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDYL.

Description E-value Query
Range
Subject
Range
gi|114605306 - gi|114605306|ref|XP_518216.2| PREDICTED: chromodomain protein, Y chromosome-like isoform 2 [Pan trog...
0.0 [1..598] [1..598]
CDYL - chromodomain protein, Y-like
0.0 [1..598] [1..598]
gi|74003862 - gi|74003862|ref|XP_848773.1| PREDICTED: similar to chromodomain protein, Y chromosome-like isoform a...
0.0 [57..598] [46..587]
gi|109069509 - gi|109069509|ref|XP_001119034.1| PREDICTED: similar to chromodomain protein, Y chromosome-like isofo...
0.0 [45..598] [121..674]
gi|32479358 - gi|32479358|gb|AAP83844.1| chromodomain Y-like protein [Macaca fascicularis]
0.0 [55..593] [1..540]
CDYL_MOUSE - Chromodomain Y-like protein OS=Mus musculus GN=Cdyl PE=1 SV=1
0.0 [20..598] [21..593]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTFQASHRSA WGKSRKKNWQ YEGPTQKLFL KRNNVSAPDG PSDPSISVSS EQSGAQQPPA  60
   61 LQVERIVDKR KNKKGKTEYL VRWKGYDSED DTWEPEQHLV NCEEYIHDFN RRHTEKQKES 120
  121 TLTRTNRTSP NNARKQISRS TN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.69897
Match: 2dntA
Description: No description for 2dntA was found.

Predicted functions:

Term Confidence Notes
chromatin binding 2.24907597884231 bayes_pls_golite062009
binding 2.08435489796069 bayes_pls_golite062009
protein binding 1.36447131532637 bayes_pls_golite062009
transcription regulator activity 0.946024766547601 bayes_pls_golite062009
transcription repressor activity 0.727533656387579 bayes_pls_golite062009
catalytic activity 0.14067200158938 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [143-200]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNFSKTSPKA LVIGKDHESK NSQLFAASQK FRKNTAPSLS SRKNMDLAKS GIKILVPK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [201-337]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPVKSRTAVD GFQSESPEKL DPVEQGQEDT VAPEVAAEKP VGALLGPGAE RARMGSRPRI  60
   61 HPLVPQVPGP VTAAMATGLA VNGKGTSPFM DALTANGTTN IQTSVTGVTA SKRKFIDDRR 120
  121 DQPFDKRLRF SVRQTES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [338-598]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AYRYRDIVVR KQDGFTHILL STKSSENNSL NPEVMREVQS ALSTAAADDS KLVLLSAVGS  60
   61 VFCCGLDFIY FIRRLTDDRK RESTKMAEAI RNFVNTFIQF KKPIIVAVNG PAIGLGASIL 120
  121 PLCDVVWANE KAWFQTPYTT FGQSPDGCST VMFPKIMGGA SANEMLLSGR KLTAQEACGK 180
  181 GLVSQVFWPG TFTQEVMVRI KELASCNPVV LEESKALVRC NMKMELEQAN ERECEVLKKI 240
  241 WGSAQGMDSM LKYLQRKIDE F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.522879
Match: 2gtrA
Description: No description for 2gtrA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle