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View Structure Prediction Details

Protein: gi|500638, gi|33...
Organism: Homo sapiens
Length: 341 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|500638, gi|33....

Description E-value Query
Range
Subject
Range
gi|76689279 - gi|76689279|ref|XP_881322.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
5.0E-44 [4..330] [186..520]
gi|73976775 - gi|73976775|ref|XP_539581.2| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
1.0E-42 [4..327] [186..518]
gi|55959639, gi|... - gi|66267552|gb|AAH94755.1| PABPC4 protein [Homo sapiens], gi|55962217|emb|CAI12298.1| poly(A) bindin...
gi|114555673 - gi|114555673|ref|XP_001170937.1| PREDICTED: poly A binding protein, cytoplasmic 4 isoform 1 [Pan tro...
1.0E-42 [4..330] [186..521]
gi|48734702 - gi|48734702|gb|AAH71591.1| PABPC4 protein [Homo sapiens]
2.0E-42 [4..330] [186..521]
gi|34785465 - gi|34785465|gb|AAH57655.1| Hnrpa3 protein [Mus musculus]
3.0E-42 [3..198] [7..202]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEREKEQFRK LFIGGLSFET TEESLRNYYE QWGKLTDCVV MRDPASKRSR GFGFVTFSSM  60
   61 AEVDAAMAAR PHSIDGRVVE PKRAVAREES GKPGAHVTVK KLFVGGIKED TEEHHLRDYF 120
  121 EEYGKIDTIE IITDRQSGKK RGFGFVTFDD HDPVDKIVLQ KYHTINGHNA EVRKALSRQE 180
  181 MQE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.0
Match: 1po6A
Description: Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [184-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQSSRSGRGG NFGFGDSRGG GGNFGPGPGS NFRGGSDGYG SGRGFGDGYN GYGGGPGGGN  60
   61 FGGSPGYGGG RGGYGGGGPG YGNQGGGYGG GYDNYGGGNY GSGNYNDFGN YNQQPSNYGP 120
  121 MKSGNFGGSR NMGGPYGGGN YGPGGSGGSG GYGGRSRY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle