YRC Public Data Repository - Protein Structure Prediction

Protein:	YJEK_ECOLI
Organism:	Escherichia coli
Length:	342 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJEK_ECOLI.

Description	E-value	Query Range	Subject Range
KAMA_CLOSU - L-lysine 2,3-aminomutase OS=Clostridium subterminale GN=kamA PE=1 SV=1	329.0	[0..4]	[340..9]
gi\|158319469, gi... - gi\|158319469\|ref\|YP_001511976.1\| lysine 2,3-aminomutase YodO family protein [Alkaliphilus oremlandii...	325.0	[0..4]	[340..10]
gi\|188594710, gi... - gi\|188995030\|ref\|YP_001929282.1\| L-lysine 2,3-aminomutase [Porphyromonas gingivalis ATCC 33277], gi\|... gi\|34397120, gi\|... - gi\|34540806\|ref\|NP_905285.1\| L-lysine 2,3-aminomutase [Porphyromonas gingivalis W83], gi\|34397120\|gb...	324.0	[0..3]	[340..9]
gi\|214035161, gi... - gi\|254478895\|ref\|ZP_05092258.1\| KamA family protein [Carboxydibrachium pacificum DSM 12653], gi\|2234... gi\|20515713, gi\|... - gi\|20807210\|ref\|NP_622381.1\| lysine 2,3-aminomutase [Thermoanaerobacter tengcongensis MB4], gi\|20515... gi\|20807210 - gi\|20807210\|ref\|NP_622381.1\| Lysine 2,3-aminomutase [Thermoanaerobacter tengcongensis MB4]	321.0	[0..7]	[340..13]
gi\|209750484, gi... - pir\|\|G91269 hypothetical protein ECs5127 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|208818769, gi... - gi\|208818769\|ref\|ZP_03259089.1\| KamA family protein [Escherichia coli O157:H7 str. EC4042], gi\|20873... gi\|15834381, gi\|... - gi\|15834381\|ref\|NP_313154.1\| hypothetical protein ECs5127 [Escherichia coli O157:H7], gi\|13364604\|db... gi\|15834381, gi\|... - gi\|15834381\|ref\|NP_313154.1\| hypothetical protein ECs5127 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|209396148, gi... - gi\|209396148\|ref\|YP_002273691.1\| KamA family protein [Escherichia coli O157:H7 str. EC4115], gi\|2091... gi\|217321394, gi... - gi\|217325173\|ref\|ZP_03441257.1\| KamA family protein [Escherichia coli O157:H7 str. TW14588], gi\|2173... gi\|189375646, gi... - gi\|189375646\|gb\|EDU94062.1\| KamA family protein [Escherichia coli O157:H7 str. EC508], gi\|168802345\|... gi\|195935938 - gi\|195935938\|ref\|ZP_03081320.1\| hypothetical protein EscherichcoliO157_05645 [Escherichia coli O157:... gi\|208728360, gi... - gi\|208808559\|ref\|ZP_03250896.1\| KamA family protein [Escherichia coli O157:H7 str. EC4206], gi\|20872... gi\|208813031, gi... - gi\|208813031\|ref\|ZP_03254360.1\| KamA family protein [Escherichia coli O157:H7 str. EC4045], gi\|20873... gi\|189363903, gi... - gi\|189363903\|gb\|EDU82322.1\| KamA family protein [Escherichia coli O157:H7 str. EC4486], gi\|168766424... gi\|187769928, gi... - gi\|187769928\|gb\|EDU33772.1\| KamA family protein [Escherichia coli O157:H7 str. EC4196], gi\|168774523... gi\|254796168, gi... - gi\|254796168\|ref\|YP_003081005.1\| lysine 2,3-aminomutase [Escherichia coli O157:H7 str. TW14359], gi\|... gi\|189001809, gi... - gi\|189001809\|gb\|EDU70795.1\| KamA family protein [Escherichia coli O157:H7 str. EC4076], gi\|168780577... gi\|189374875, gi... - gi\|189374875\|gb\|EDU93291.1\| KamA family protein [Escherichia coli O157:H7 str. EC869], gi\|168784782\|... gi\|168747993, gi... - gi\|188017568\|gb\|EDU55690.1\| KamA family protein [Escherichia coli O157:H7 str. EC4113], gi\|168747993... gi\|189357403, gi... - gi\|189357403\|gb\|EDU75822.1\| KamA family protein [Escherichia coli O157:H7 str. EC4401], gi\|168755334... gi\|168761014, gi... - gi\|189368518\|gb\|EDU86934.1\| KamA family protein [Escherichia coli O157:H7 str. EC4501], gi\|168761014...	320.0	[0..1]	[336..1]
gi\|26111471, gi\|... - gi\|26251039\|ref\|NP_757079.1\| hypothetical protein c5231 [Escherichia coli CFT073], gi\|26111471\|gb\|AA... gi\|227836152, gi... - gi\|227886810\|ref\|ZP_04004615.1\| lysine 2,3-aminomutase [Escherichia coli 83972], gi\|227836152\|gb\|EEJ...	320.0	[0..1]	[336..1]
gi\|218368075, gi... - gi\|218561306\|ref\|YP_002394219.1\| putative lysine aminomutase [Escherichia coli S88], gi\|218368075\|em... gi\|237703813, gi... - gi\|237703813\|ref\|ZP_04534294.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22690... gi\|110644505, gi... - gi\|110644505\|ref\|YP_672235.1\| hypothetical protein ECP_4390 [Escherichia coli 536], gi\|110346097\|gb\|... gi\|91075270, gi\|... - gi\|91213696\|ref\|YP_543682.1\| hypothetical protein UTI89_C4744 [Escherichia coli UTI89], gi\|91075270\|... gi\|117626495, gi... - gi\|117626495\|ref\|YP_859818.1\| putative lysine aminomutase [Escherichia coli APEC O1], gi\|115515619\|g... gi\|190906333, gi... - gi\|75239115\|ref\|ZP_00723095.1\| COG1509: Lysine 2,3-aminomutase [Escherichia coli F11], gi\|191173357\|...	320.0	[0..1]	[336..1]
gi\|81243566, gi\|... - gi\|82779418\|ref\|YP_405767.1\| hypothetical protein SDY_4389 [Shigella dysenteriae Sd197], gi\|81243566...	319.0	[0..1]	[336..1]

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Predicted Domain #1

Region A:
Residues: [1-342]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAHIVTLNTP SREDWLTQLA DVVTDPDELL RLLNIDAEEK LLAGRSAKKL FALRVPRSFI  60
   61 DRMEKGNPDD PLLRQVLTSQ DEFVIAPGFS TDPLEEQHSV VPGLLHKYHN RALLLVKGGC 120
  121 AVNCRYCFRR HFPYAENQGN KRNWQTALEY VAAHPELDEM IFSGGDPLMA KDHELDWLLT 180
  181 QLEAIPHIKR LRIHSRLPIV IPARITEALV ECFARSTLQI LLVNHINHAN EVDETFRQAM 240
  241 AKLRRVGVTL LNQSVLLRDV NDNAQTLANL SNALFDAGVM PYYLHVLDKV QGAAHFMVSD 300
  301 DEARQIMREL LTLVSGYLVP KLAREIGGEP SKTPLDLQLR QQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	90.09691
Match:	2a5hA
Description:	2.1 Angstrom X-ray crystal structure of lysine-2,3-aminomutase from Clostridium subterminale SB4, with Michaelis analog (L-alpha-lysine external aldimine form of pyridoxal-5'-phosphate).
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits