YRC Public Data Repository - Protein Structure Prediction

Protein:	YIEC_ECOLI
Organism:	Escherichia coli
Length:	538 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIEC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|194425266, gi... - gi\|194435723\|ref\|ZP_03067826.1\| glucoside specific outer membrane porin BglH [Escherichia coli 101-1... BGLH_SHISS - Putative outer membrane porin BglH OS=Shigella sonnei (strain Ss046) GN=bglH PE=3 SV=1 gi\|226838903, gi... - gi\|254038938\|ref\|ZP_04872990.1\| glucoside specific outer membrane porin BglH [Escherichia sp. 1_1_43... gi\|218363056, gi... - gi\|218556287\|ref\|YP_002389201.1\| carbohydrate-specific outer membrane porin, cryptic [Escherichia co... gi\|209921197, gi... - gi\|209921197\|ref\|YP_002295281.1\| hypothetical protein ECSE_4006 [Escherichia coli SE11], gi\|20991445...	596.0	[0..1]	[538..1]
BGLH_ECOL5 - Putative outer membrane porin BglH OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=bglH PE=3 S... gi\|190909307, gi... - gi\|191170499\|ref\|ZP_03032052.1\| glucoside specific outer membrane porin BglH [Escherichia coli F11],...	592.0	[0..1]	[538..1]
BGLH_ECOL6 - Putative outer membrane porin BglH OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN... gi\|227883941, gi... - gi\|227883941\|ref\|ZP_04001746.1\| carbohydrate-specific outer membrane porin, cryptic [Escherichia col... BGLH_ECOL6 - Putative outer membrane porin BglH OS=Escherichia coli O6 GN=bglH PE=3 SV=1	591.0	[0..1]	[538..1]
BGLH_ECOUT - Putative outer membrane porin BglH OS=Escherichia coli (strain UTI89 / UPEC) GN=bglH PE=3 SV=1 gi\|218367564, gi... - gi\|218560795\|ref\|YP_002393708.1\| carbohydrate-specific outer membrane porin, cryptic [Escherichia co... BGLH_ECOK1 - Putative outer membrane porin BglH OS=Escherichia coli O1:K1 / APEC GN=bglH PE=3 SV=1	590.0	[0..1]	[538..1]
BGLH_SHIF8 - Putative outer membrane porin BglH OS=Shigella flexneri serotype 5b (strain 8401) GN=bglH PE=3 SV=1	588.0	[0..1]	[538..1]
gi\|75514219 - gi\|75514219\|ref\|ZP_00736527.1\| COG4580: Maltoporin (phage lambda and maltose receptor) [Escherichia ... gi\|75197616 - gi\|75197616\|ref\|ZP_00707686.1\| COG4580: Maltoporin (phage lambda and maltose receptor) [Escherichia ...	578.0	[0..14]	[538..1]
gi\|75188475 - gi\|75188475\|ref\|ZP_00701742.1\| COG4580: Maltoporin (phage lambda and maltose receptor) [Escherichia ...	578.0	[0..14]	[538..1]
gi\|83588415 - gi\|83588415\|ref\|ZP_00927039.1\| COG4580: Maltoporin (phage lambda and maltose receptor) [Escherichia ... gi\|75236449 - gi\|75236449\|ref\|ZP_00720545.1\| COG4580: Maltoporin (phage lambda and maltose receptor) [Escherichia ...	577.0	[0..14]	[538..1]
gi\|75231010 - gi\|75231010\|ref\|ZP_00717445.1\| COG4580: Maltoporin (phage lambda and maltose receptor) [Escherichia ...	576.0	[0..14]	[538..1]
gi\|75210670 - gi\|75210670\|ref\|ZP_00710811.1\| COG4580: Maltoporin (phage lambda and maltose receptor) [Escherichia ...	575.0	[0..14]	[538..1]

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Predicted Domain #1

Region A:
Residues: [1-105]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRRNLITSA ILLMAPLAFS AQSLAESLTV EQRLELLEKA LRETQSELKK YKDEEKKKYT  60
   61 PATVNRSVST NDQGYAANPF PTSSAAKPDA VLVKNEEKNA SETGS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [106-538]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IYSSMTLKDF SKFVKDEIGF SYNGYYRSGW GTASHGSPKS WAIGSLGRFG NEYSGWFDLQ  60
   61 LKQRVYNENG KRVDAVVMMD GNVGQQYSTG WFGDNAGGEN YMQFSDMYVT TKGFLPFAPE 120
  121 ADFWVGKHGA PKIEIQMLDW KTQRTDAAAG VGLENWKVGP GKIDIALVRE DVDDYDRSLQ 180
  181 NKQQINTNTI DLRYKDIPLW DKATLMVSGR YVTANESASE KDNQDNNGYY DWKDTWMFGT 240
  241 SLTQKFDKGG FNEFSFLVAN NSIASNFGRY AGASPFTTFN GRYYGDHTGG TAVRLTSQGE 300
  301 AYIGDHFIVA NAIVYSFGND IYSYETGAHS DFESIRAVVR PAYIWDQYNQ TGVELGYFTQ 360
  361 QNKDANSNKF NESGYKTTLF HTFKVNTSML TSRPEIRFYA TYIKALENEL DGFTFEDNKD 420
  421 DQFAVGAQAE IWW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	114.0
Match:	1af6A
Description:	Maltoporin (also LamB protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	2.60507547654721	bayes_pls_golite062009
maltose transmembrane transporter activity	2.28670706859872	bayes_pls_golite062009
alpha-glucoside transmembrane transporter activity	2.28670706859872	bayes_pls_golite062009
disaccharide transmembrane transporter activity	2.28670706859872	bayes_pls_golite062009
glucoside transmembrane transporter activity	1.6013750628135	bayes_pls_golite062009
substrate-specific transporter activity	0.86109425700917	bayes_pls_golite062009
transmembrane transporter activity	0.424956094980482	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	0.33560812495796	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: