YRC Public Data Repository - Protein Structure Prediction

Protein:	YHBZ_ECOLI
Organism:	Escherichia coli
Length:	390 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YHBZ_ECOLI.

Description	E-value	Query Range	Subject Range
OBG_IDILO - GTPase obg OS=Idiomarina loihiensis GN=obg PE=3 SV=1 OBG_IDILO - GTPase Obg OS=Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR) GN=obg PE=3 SV=1	339.0	[0..1]	[357..1]
gi\|238724369, gi... - gi\|77974006\|ref\|ZP_00829549.1\| COG0536: Predicted GTPase [Yersinia frederiksenii ATCC 33641], gi\|238...	338.0	[0..1]	[390..1]
OBG_ACTSZ - GTPase Obg OS=Actinobacillus succinogenes (strain ATCC 55618 / 130Z) GN=obg PE=3 SV=1	338.0	[0..1]	[390..1]
OBG_SODGM - GTPase Obg OS=Sodalis glossinidius (strain morsitans) GN=obg PE=3 SV=1	337.0	[0..1]	[390..1]
gi\|188491854, gi... - gi\|75510980\|ref\|ZP_00733739.1\| COG0536: Predicted GTPase [Escherichia coli 53638], gi\|188491854\|ref\|... gi\|191174476, gi... - gi\|75236237\|ref\|ZP_00720347.1\| COG0536: Predicted GTPase [Escherichia coli F11], gi\|191174476\|ref\|ZP... gi\|189374127, gi... - gi\|189374127\|gb\|EDU92543.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC869], gi\|1... gi\|13363535, gi\|... - gi\|15833316\|ref\|NP_312089.1\| GTPase ObgE [Escherichia coli O157:H7 str. Sakai], gi\|13363535\|dbj\|BAB3... gi\|168781327, gi... - gi\|189001085\|gb\|EDU70071.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC4076], gi\|... OBG_ECOL5 - GTPase Obg OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=obg PE=3 SV=1 gi\|208727362, gi... - gi\|208807561\|ref\|ZP_03249898.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC4206],... gi\|195938402 - gi\|195938402\|ref\|ZP_03083784.1\| GTPase ObgE [Escherichia coli O157:H7 str. EC4024] gi\|208742116, gi... - gi\|208821993\|ref\|ZP_03262313.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC4042],... gi\|208735131, gi... - gi\|208813854\|ref\|ZP_03255183.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC4045],... gi\|217320124, gi... - gi\|217327757\|ref\|ZP_03443840.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. TW14588]... OBG_ECO5E - GTPase Obg OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=obg PE=3 SV=1 gi\|168769039, gi... - gi\|189361859\|gb\|EDU80278.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC4486], gi\|... gi\|189358740, gi... - gi\|189358740\|gb\|EDU77159.1\| GTP-binding protein Obg/CgtA [Escherichia coli O157:H7 str. EC4401], gi\|... gi\|209758208, gi... - pir\|\|A85982 probable GTP-binding factor yhbZ [imported] - Escherichia coli (strain O157:H7, substrai... OBG_ECO57 - GTPase Obg OS=Escherichia coli O157:H7 GN=obg PE=3 SV=1 OBG_ECOL6 - GTPase Obg OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=obg PE=3 SV=1 OBG_ECO45 - GTPase Obg OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=obg PE=3 SV=1 gi\|12517798, gi\|... - gi\|15803723\|ref\|NP_289757.1\| GTPase ObgE [Escherichia coli O157:H7 EDL933], gi\|12517798\|gb\|AAG58317.... gi\|227887904, gi... - gi\|227887904\|ref\|ZP_04005709.1\| GTP-binding protein [Escherichia coli 83972], gi\|227835300\|gb\|EEJ457... OBG_ECOK1 - GTPase Obg OS=Escherichia coli O1:K1 / APEC GN=obg PE=3 SV=1 gi\|226899105, gi... - gi\|237706065\|ref\|ZP_04536546.1\| GTPase ObgE [Escherichia sp. 3_2_53FAA], gi\|226899105\|gb\|EEH85364.1\|... gi\|254038348, gi... - gi\|254038348\|ref\|ZP_04872406.1\| GTPase ObgE [Escherichia sp. 1_1_43], gi\|226839972\|gb\|EEH71993.1\| GT... gi\|254795132, gi... - gi\|254795132\|ref\|YP_003079969.1\| GTPase involved in cell partioning and DNA repair [Escherichia coli... OBG_ECOL6 - GTPase obg OS=Escherichia coli O6 GN=obg PE=3 SV=1	335.0	[0..1]	[390..1]
gi\|52629966, gi\|... - gi\|52842855\|ref\|YP_096654.1\| GTP-binding protein, GTP1/Obg family [Legionella pneumophila subsp. pne...	333.0	[0..1]	[335..59]
gi\|238783528, gi... - gi\|77958778\|ref\|ZP_00822806.1\| COG0536: Predicted GTPase [Yersinia bercovieri ATCC 43970], gi\|238783...	332.0	[0..1]	[361..1]
OBG_PASMU - GTPase obg OS=Pasteurella multocida GN=obg PE=3 SV=1 OBG_PASMU - GTPase Obg OS=Pasteurella multocida (strain Pm70) GN=obg PE=3 SV=1	332.0	[0..1]	[364..1]
gi\|42630290 - gi\|42630290\|ref\|ZP_00155834.1\| COG0536: Predicted GTPase [Haemophilus influenzae R2846]	331.0	[0..1]	[364..1]
gi\|238718562, gi... - gi\|77961856\|ref\|ZP_00825685.1\| COG0536: Predicted GTPase [Yersinia mollaretii ATCC 43969], gi\|238797...	331.0	[0..1]	[361..1]

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Predicted Domain #1

Region A:
Residues: [1-390]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFVDEASIL VVAGDGGNGC VSFRREKYIP KGGPDGGDGG DGGDVWMEAD ENLNTLIDYR  60
   61 FEKSFRAERG QNGASRDCTG KRGKDVTIKV PVGTRVIDQG TGETMGDMTK HGQRLLVAKG 120
  121 GWHGLGNTRF KSSVNRTPRQ KTNGTPGDKR ELLLELMLLA DVGMLGMPNA GKSTFIRAVS 180
  181 AAKPKVADYP FTTLVPSLGV VRMDNEKSFV VADIPGLIEG AAEGAGLGIR FLKHLERCRV 240
  241 LLHLIDIDPI DGTDPVENAR IIISELEKYS QDLATKPRWL VFNKIDLLDK VEAEEKAKAI 300
  301 AEALGWEDKY YLISAASGLG VKDLCWDVMT FIIENPVVQA EEAKQPEKVE FMWDDYHRQQ 360
  361 LEEIAEEDDE DWDDDWDEDD EEGVEFIYKR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	84.221849
Match:	1lnzA
Description:	Obg GTP-binding protein N-terminal domain; Obg GTP-binding protein C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.828877635849693	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.724314026597703	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.723703267640935	bayes_pls_golite062009
binding	0.671939534213175	bayes_pls_golite062009
pyrophosphatase activity	0.42243458498398	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: