YRC Public Data Repository - Protein Structure Prediction

Protein:	YGAV_ECOLI
Organism:	Escherichia coli
Length:	99 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGAV_ECOLI.

Description	E-value	Query Range	Subject Range
Y1325_METJA, YD2... - (Q58721) Putative HTH-type transcriptional regulator MJ1325, Uncharacterized HTH-type transcriptiona... Y1325_METJA - Uncharacterized HTH-type transcriptional regulator MJ1325 OS=Methanocaldococcus jannaschii (strain A... gi\|255051040, gi... - gi\|255051040\|ref\|ZP_05303303.1\| transcriptional regulator, ArsR family [Methanocaldococcus vulcanius...	114.0	[0..8]	[96..1]
gi\|82778036, gi\|... - gi\|82778036\|ref\|YP_404385.1\| hypothetical protein SDY_2857 [Shigella dysenteriae Sd197], gi\|81242184...	107.0	[0..1]	[99..1]
gi\|208726573, gi... - gi\|208806772\|ref\|ZP_03249109.1\| transcriptional regulator, ArsR family [Escherichia coli O157:H7 str... gi\|208812286, gi... - gi\|208812286\|ref\|ZP_03253615.1\| transcriptional regulator, ArsR family [Escherichia coli O157:H7 str... gi\|208741391, gi... - gi\|208821268\|ref\|ZP_03261588.1\| transcriptional regulator, ArsR family [Escherichia coli O157:H7 str... gi\|209397295, gi... - gi\|209397295\|ref\|YP_002272131.1\| transcriptional regulator, ArsR family [Escherichia coli O157:H7 st... gi\|168778645, gi... - gi\|189003587\|gb\|EDU72573.1\| transcriptional regulator, ArsR family [Escherichia coli O157:H7 str. EC... gi\|168789569, gi... - gi\|189370873\|gb\|EDU89289.1\| transcriptional regulator, ArsR family [Escherichia coli O157:H7 str. EC... gi\|168800548, gi... - gi\|189377161\|gb\|EDU95577.1\| transcriptional regulator, ArsR family [Escherichia coli O157:H7 str. EC... gi\|195938419 - gi\|195938419\|ref\|ZP_03083801.1\| hypothetical protein EscherichcoliO157_18635 [Escherichia coli O157:... gi\|168755408, gi... - gi\|189357335\|gb\|EDU75754.1\| transcriptional regulator, ArsR family [Escherichia coli O157:H7 str. EC... gi\|189367232, gi... - gi\|189367232\|gb\|EDU85648.1\| transcriptional regulator, ArsR family [Escherichia coli O157:H7 str. EC... gi\|189362038, gi... - gi\|189362038\|gb\|EDU80457.1\| transcriptional regulator, ArsR family [Escherichia coli O157:H7 str. EC... gi\|168774804, gi... - gi\|187769525\|gb\|EDU33369.1\| transcriptional regulator, ArsR family [Escherichia coli O157:H7 str. EC... gi\|188014954, gi... - gi\|188014954\|gb\|EDU53076.1\| transcriptional regulator, ArsR family [Escherichia coli O157:H7 str. EC... gi\|15832782, gi\|... - gi\|15832782\|ref\|NP_311555.1\| hypothetical protein ECs3528 [Escherichia coli O157:H7], gi\|13362999\|db... gi\|209762330, gi... - pir\|\|H91069 hypothetical protein ECs3528 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|12517101, gi\|... - gi\|15803185\|ref\|NP_289217.1\| hypothetical protein Z3966 [Escherichia coli O157:H7 EDL933], gi\|125171... gi\|15832782, gi\|... - gi\|15832782\|ref\|NP_311555.1\| hypothetical protein ECs3528 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|217320259, gi... - gi\|217327892\|ref\|ZP_03443975.1\| transcriptional regulator, ArsR family [Escherichia coli O157:H7 str... gi\|254594011, gi... - gi\|254794611\|ref\|YP_003079448.1\| predicted DNA-binding transcriptional regulator [Escherichia coli O...	107.0	[0..1]	[99..1]
gi\|72161958, gi\|... - gi\|72161958\|ref\|YP_289615.1\| ArsR family transcriptional regulator [Thermobifida fusca YX], gi\|71915...	107.0	[0..7]	[99..26]
gi\|16421345, gi\|... - gi\|16766108\|ref\|NP_461723.1\| putative regulatory protein [Salmonella typhimurium LT2], gi\|16421345\|g... gi\|206709868, gi... - gi\|207858065\|ref\|YP_002244716.1\| putative ArsR-family regulatory protein [Salmonella enterica subsp.... gi\|204929681, gi... - gi\|204929681\|ref\|ZP_03220755.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serova... lcl\|NC_016856.1_... - [gene=STM14_3374] [protein=putative regulatory protein] [protein_id=YP_005238889.1] [location=296627... gi\|205273529, gi... - gi\|205353748\|ref\|YP_002227549.1\| putative ArsR-family regulatory protein [Salmonella enterica subsp.... gi\|197264482, gi... - gi\|197264482\|ref\|ZP_03164556.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serova... gi\|198244582, gi... - gi\|198244582\|ref\|YP_002216769.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serov... gi\|194444472, gi... - gi\|194444472\|ref\|YP_002042039.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serov... gi\|194469448, gi... - gi\|194469448\|ref\|ZP_03075432.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serova... gi\|168233754, gi... - gi\|205332198\|gb\|EDZ18962.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serovar Ke... gi\|168262098, gi... - gi\|205349310\|gb\|EDZ35941.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serovar Ha... gi\|56129012, gi\|... - gi\|56414755\|ref\|YP_151830.1\| putative transcriptional regulator [Salmonella enterica subsp. enterica... gi\|205329260, gi... - gi\|205329260\|gb\|EDZ16024.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serovar 4,... gi\|238909567 - gi\|238909567\|ref\|ZP_04653404.1\| putative ArsR-family regulatory protein [Salmonella enterica subsp. ...	106.0	[0..1]	[99..1]
gi\|213613087 - gi\|213613087\|ref\|ZP_03370913.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serova... gi\|213650074 - gi\|213650074\|ref\|ZP_03380127.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serova... gi\|213864804 - gi\|213864804\|ref\|ZP_03386923.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serova... gi\|213981341 - gi\|213981341\|ref\|ZP_03408600.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serova... gi\|213025970 - gi\|213025970\|ref\|ZP_03340417.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serova... gi\|213053445 - gi\|213053445\|ref\|ZP_03346323.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serova... gi\|213424565 - gi\|213424565\|ref\|ZP_03357354.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serova... gi\|213580993 - gi\|213580993\|ref\|ZP_03362819.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serova... gi\|29138691, gi\|... - gi\|29143058\|ref\|NP_806400.1\| putative transcriptional regulator [Salmonella enterica subsp. enterica... gi\|16761578 - gi\|16761578\|ref\|NP_457195.1\| putative transcriptional regulator [Salmonella enterica subsp. enterica... gi\|16503879, gi\|... - gi\|25300805\|pir\|\|AC0840 probable transcription regulator STY2917 [imported] - Salmonella enterica su... gi\|213999978 - gi\|213999978\|ref\|ZP_03410713.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serova...	106.0	[0..1]	[99..1]
gi\|199605063, gi... - gi\|200387965\|ref\|ZP_03214577.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serova... gi\|197251611, gi... - gi\|197251611\|ref\|YP_002147693.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serov... gi\|194447388, gi... - gi\|194447388\|ref\|YP_002046757.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serov... gi\|205340772, gi... - gi\|205340772\|gb\|EDZ27536.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serovar We... gi\|168464087, gi... - gi\|195633307\|gb\|EDX51721.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serovar Ne... gi\|168244591, gi... - gi\|205336545\|gb\|EDZ23309.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serovar He... gi\|167552707, gi... - gi\|205322716\|gb\|EDZ10555.1\| regulatory protein, ArsR [Salmonella enterica subsp. enterica serovar Sa... gi\|161365052, gi... - gi\|161615688\|ref\|YP_001589653.1\| hypothetical protein SPAB_03473 [Salmonella enterica subsp. enteric... gi\|62181299, gi\|... - gi\|62181299\|ref\|YP_217716.1\| ArsR family regulatory protein [Salmonella enterica subsp. enterica ser... gi\|224584579, gi... - gi\|224584579\|ref\|YP_002638377.1\| putative transcriptional regulator [Salmonella enterica subsp. ente...	106.0	[0..1]	[99..1]
gi\|24113971, gi\|... - gi\|24113971\|ref\|NP_708481.1\| hypothetical protein SF2695 [Shigella flexneri 2a str. 301], gi\|2405308... gi\|30064035, gi\|... - gi\|30064035\|ref\|NP_838206.1\| hypothetical protein S2881 [Shigella flexneri 2a str. 2457T], gi\|300422... gi\|110616248, gi... - gi\|110806700\|ref\|YP_690220.1\| hypothetical protein SFV_2836 [Shigella flexneri 5 str. 8401], gi\|1106...	105.0	[0..1]	[99..1]
gi\|90417861, gi\|... - gi\|90417861\|ref\|ZP_01225773.1\| transcriptional regulatory protein, ArsR family [Aurantimonas sp. SI8... gi\|90417861, gi\|... - gi\|90417861\|ref\|ZP_01225773.1\| transcriptional regulatory protein, ArsR family [Aurantimonas sp. SI8...	105.0	[0..2]	[98..63]
gi\|187428746, gi... - gi\|75178700\|ref\|ZP_00698736.1\| COG0640: Predicted transcriptional regulators [Shigella boydii BS512]...	104.0	[0..1]	[99..1]

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Predicted Domain #1

Region A:
Residues: [1-99]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTELAQLQAS AEQAAALLKA MSHPKRLLIL CMLSGSPGTS AGELTRITGL SASATSQHLA  60
   61 RMRDEGLIDS QRDAQRILYS IKNEAVNAII ATLKNVYCP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.69897
Match:	1u2wA
Description:	Crystal Structure of the Staphylococcus aureus pI258 CadC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.835523092977445	bayes_pls_golite062009
transcription regulator activity	0.4843036104266	bayes_pls_golite062009
nucleic acid binding	0.37117756729668	bayes_pls_golite062009
DNA binding	0.3118855114645	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: