YRC Public Data Repository - Protein Structure Prediction

Protein:	YFIO_ECOLI
Organism:	Escherichia coli
Length:	245 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YFIO_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|71675440, gi\|... - gi\|71675440\|ref\|ZP_00673185.1\| TPR repeat:Sel1-like repeat [Trichodesmium erythraeum IMS101], gi\|716...	200.0	[0..17]	[244..1080]
gi\|72002781, gi\|... - gi\|72382931\|ref\|YP_292286.1\| TPR repeat-containing protein [Prochlorococcus marinus str. NATL2A], gi...	194.0	[0..22]	[244..150]
gi\|46119331, gi\|... - gi\|67923599\|ref\|ZP_00517071.1\| TPR repeat:TPR repeat [Crocosphaera watsonii WH 8501], gi\|67854569\|gb...	194.0	[0..17]	[244..209]
gi\|23123830 - gi\|23123830\|ref\|ZP_00105868.1\| COG0457: FOG: TPR repeat [Nostoc punctiforme PCC 73102]	190.0	[0..17]	[244..253]
gi\|40063048 - gi\|40063048\|gb\|AAR37904.1\| TPR domain protein [uncultured marine bacterium 560]	189.0	[0..21]	[244..64]
gi\|40063716 - gi\|40063716\|gb\|AAR38497.1\| TPR repeat protein [uncultured marine bacterium 583]	188.0	[0..21]	[244..64]

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Predicted Domain #1

Region A:
Residues: [1-245]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRMKYLVAA ATLSLFLAGC SGSKEEVPDN PPNEIYATAQ QKLQDGNWRQ AITQLEALDN  60
   61 RYPFGPYSQQ VQLDLIYAYY KNADLPLAQA AIDRFIRLNP THPNIDYVMY MRGLTNMALD 120
  121 DSALQGFFGV DRSDRDPQHA RAAFSDFSKL VRGYPNSQYT TDATKRLVFL KDRLAKYEYS 180
  181 VAEYYTERGA WVAVVNRVEG MLRDYPDTQA TRDALPLMEN AYRQMQMNAQ AEKVAKIIAA 240
  241 NSSNT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.0
Match:	1w3bA
Description:	The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.25418044968722	bayes_pls_golite062009
protein binding	1.17586390384786	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: