YRC Public Data Repository - Protein Structure Prediction

Protein:	YFGC_ECOLI
Organism:	Escherichia coli
Length:	487 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YFGC_ECOLI.

Description	E-value	Query Range	Subject Range
BEPA_SALTI - Beta-barrel assembly-enhancing protease OS=Salmonella typhi GN=bepA PE=3 SV=1 gi\|195630846, gi... - gi\|195630846\|gb\|EDX49438.1\| TPR repeat-containing protein YfgC [Salmonella enterica subsp. enterica ... BEPA_SALTY - Beta-barrel assembly-enhancing protease OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 7007... gi\|205349510, gi... - gi\|205349510\|gb\|EDZ36141.1\| TPR repeat-containing protein YfgC [Salmonella enterica subsp. enterica ... gi\|205337707, gi... - gi\|205337707\|gb\|EDZ24471.1\| TPR repeat-containing protein YfgC [Salmonella enterica subsp. enterica ... gi\|168232043, gi... - gi\|205333610\|gb\|EDZ20374.1\| TPR repeat-containing protein YfgC [Salmonella enterica subsp. enterica ... YFGC_SALTI - TPR repeat-containing protein yfgC OS=Salmonella typhi GN=yfgC PE=4 SV=1 gi\|197262697, gi... - gi\|197262697\|ref\|ZP_03162771.1\| TPR repeat-containing protein YfgC [Salmonella enterica subsp. enter... gi\|194448280, gi... - gi\|194448280\|ref\|YP_002046557.1\| TPR repeat-containing protein YfgC [Salmonella enterica subsp. ente... gi\|29140891, gi\|... - gi\|29140891\|ref\|NP_804233.1\| hypothetical protein t0363 [Salmonella enterica subsp. enterica serovar... gi\|194403506, gi... - gi\|194444843\|ref\|YP_002041755.1\| TPR repeat-containing protein YfgC [Salmonella enterica subsp. ente... YFGC_SALTY - TPR repeat-containing protein yfgC OS=Salmonella typhimurium GN=yfgC PE=4 SV=1 gi\|16761412 - gi\|16761412\|ref\|NP_457029.1\| hypothetical protein STY2735 [Salmonella enterica subsp. enterica serov... gi\|205344865, gi... - gi\|205344865\|gb\|EDZ31629.1\| TPR repeat-containing protein YfgC [Salmonella enterica subsp. enterica ... gi\|167991799, gi... - gi\|205329851\|gb\|EDZ16615.1\| TPR repeat-containing protein YfgC [Salmonella enterica subsp. enterica ... gi\|167549488, gi... - gi\|205325408\|gb\|EDZ13247.1\| TPR repeat-containing protein YfgC [Salmonella enterica subsp. enterica ... gi\|161362117, gi... - gi\|161612753\|ref\|YP_001586718.1\| hypothetical protein SPAB_00452 [Salmonella enterica subsp. enteric... gi\|213160891 - gi\|213160891\|ref\|ZP_03346601.1\| hypothetical protein Salmoneentericaenterica_12903 [Salmonella enter... gi\|206709710, gi... - gi\|207857907\|ref\|YP_002244558.1\| hypothetical protein SEN2475 [Salmonella enterica subsp. enterica s... gi\|205273380, gi... - gi\|205353599\|ref\|YP_002227400.1\| hypothetical protein SG2526 [Salmonella enterica subsp. enterica se... lcl\|NC_016856.1_... - [gene=STM14_3058] [protein=hypothetical protein] [protein_id=YP_005238586.1] [location=2659523..2660... gi\|198242783, gi... - gi\|198242783\|ref\|YP_002216563.1\| TPR repeat-containing protein YfgC [Salmonella enterica subsp. ente... gi\|238913633 - gi\|238913633\|ref\|ZP_04657470.1\| hypothetical protein SentesTe_21223 [Salmonella enterica subsp. ente... gi\|214002882 - gi\|214002882\|ref\|ZP_03413617.1\| hypothetical protein Salmonellentericaenterica_22266 [Salmonella ent... gi\|213855524 - gi\|213855524\|ref\|ZP_03383764.1\| hypothetical protein SentesT_16335 [Salmonella enterica subsp. enter... YFGC_SALTY - TPR repeat-containing protein yfgC OS=Salmonella typhimurium GN=yfgC PE=4 SV=1	257.0	[0..1]	[487..1]
gi\|115513802, gi... - gi\|117624678\|ref\|YP_853591.1\| putative peptidase YfgC [Escherichia coli APEC O1], gi\|115513802\|gb\|AB... gi\|218559418, gi... - gi\|218559418\|ref\|YP_002392331.1\| putative peptidase [Escherichia coli S88], gi\|218366187\|emb\|CAR0393...	255.0	[0..1]	[487..1]
gi\|110642656, gi... - gi\|110642656\|ref\|YP_670386.1\| hypothetical protein ECP_2496 [Escherichia coli 536], gi\|110344248\|gb\|... gi\|75240132, gi\|... - gi\|75240132\|ref\|ZP_00724091.1\| COG4783: Putative Zn-dependent protease, contains TPR repeats [Escher...	255.0	[0..1]	[487..1]
gi\|73856497, gi\|... - gi\|74313020\|ref\|YP_311439.1\| hypothetical protein SSON_2576 [Shigella sonnei Ss046], gi\|73856497\|gb\|...	255.0	[0..1]	[487..1]
gi\|224582972, gi... - gi\|224582972\|ref\|YP_002636770.1\| hypothetical protein SPC_1163 [Salmonella enterica subsp. enterica ... gi\|62128694, gi\|... - gi\|62181061\|ref\|YP_217478.1\| hypothetical protein SC2491 [Salmonella enterica subsp. enterica serova...	255.0	[0..1]	[487..1]
gi\|26248853, gi\|... - gi\|26248853\|ref\|NP_754893.1\| hypothetical protein c3011 [Escherichia coli CFT073], gi\|26109259\|gb\|AA... gi\|227835873, gi... - gi\|227887523\|ref\|ZP_04005328.1\| M48 family peptidase [Escherichia coli 83972], gi\|227835873\|gb\|EEJ46... gi\|237705000, gi... - gi\|237705000\|ref\|ZP_04535481.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22690...	255.0	[0..1]	[487..1]
gi\|15803017, gi\|... - gi\|15803017\|ref\|NP_289047.1\| hypothetical protein Z3757 [Escherichia coli O157:H7 EDL933], gi\|125168... gi\|209763582, gi... - pir\|\|H85892 hypothetical protein Z3757 [imported] - Escherichia coli (strain O157:H7, substrain EDL... gi\|254794439, gi... - gi\|254794439\|ref\|YP_003079276.1\| predicted peptidase [Escherichia coli O157:H7 str. TW14359], gi\|254... gi\|208734566, gi... - gi\|208813289\|ref\|ZP_03254618.1\| peptidase, M48 family [Escherichia coli O157:H7 str. EC4045], gi\|208... gi\|208820816, gi... - gi\|208820816\|ref\|ZP_03261136.1\| peptidase, M48 family [Escherichia coli O157:H7 str. EC4042], gi\|208... gi\|209399555, gi... - gi\|209399555\|ref\|YP_002271963.1\| peptidase, M48 family [Escherichia coli O157:H7 str. EC4115], gi\|20... gi\|217319540, gi... - gi\|217327173\|ref\|ZP_03443256.1\| peptidase, M48 family [Escherichia coli O157:H7 str. TW14588], gi\|21... gi\|13362826, gi\|... - gi\|15832610\|ref\|NP_311383.1\| hypothetical protein ECs3356 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|189372296, gi... - gi\|189372296\|gb\|EDU90712.1\| peptidase, M48 family [Escherichia coli O157:H7 str. EC869], gi\|16878783... gi\|189378648, gi... - gi\|189378648\|gb\|EDU97064.1\| peptidase, M48 family [Escherichia coli O157:H7 str. EC508], gi\|16879886... gi\|195936637 - gi\|195936637\|ref\|ZP_03082019.1\| hypothetical protein EscherichcoliO157_09275 [Escherichia coli O157:... gi\|208728030, gi... - gi\|208808229\|ref\|ZP_03250566.1\| peptidase, M48 family [Escherichia coli O157:H7 str. EC4206], gi\|208... gi\|168761101, gi... - gi\|189368366\|gb\|EDU86782.1\| peptidase, M48 family [Escherichia coli O157:H7 str. EC4501], gi\|1687611... gi\|168768584, gi... - gi\|189362217\|gb\|EDU80636.1\| peptidase, M48 family [Escherichia coli O157:H7 str. EC4486], gi\|1687685... BEPA_ECO57 - Beta-barrel assembly-enhancing protease OS=Escherichia coli O157:H7 GN=bepA PE=3 SV=1 gi\|187770572, gi... - gi\|187770572\|gb\|EDU34416.1\| peptidase, M48 family [Escherichia coli O157:H7 str. EC4196], gi\|1687735... gi\|189003191, gi... - gi\|189003191\|gb\|EDU72177.1\| peptidase, M48 family [Escherichia coli O157:H7 str. EC4076], gi\|1687784... gi\|188017078, gi... - gi\|188017078\|gb\|EDU55200.1\| peptidase, M48 family [Escherichia coli O157:H7 str. EC4113], gi\|1687484... gi\|189356561, gi... - gi\|189356561\|gb\|EDU74980.1\| peptidase, M48 family [Escherichia coli O157:H7 str. EC4401], gi\|1687562...	254.0	[0..1]	[487..1]
gi\|91211815, gi\|... - gi\|91211815\|ref\|YP_541801.1\| hypothetical protein UTI89_C2810 [Escherichia coli UTI89], gi\|91073389\|...	254.0	[0..1]	[487..1]
gi\|188494540, gi... - gi\|75515835\|ref\|ZP_00737970.1\| COG4783: Putative Zn-dependent protease, contains TPR repeats [Escher...	253.0	[0..1]	[487..1]
gi\|81246352, gi\|... - gi\|82544941\|ref\|YP_408888.1\| hypothetical protein SBO_2515 [Shigella boydii Sb227], gi\|81246352\|gb\|A...	253.0	[0..1]	[487..1]

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Predicted Domain #1

Region A:
Residues: [1-137]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRQLKKNLV ATLIAAMTIG QVAPAFADSA DTLPDMGTSA GSTLSIGQEM QMGDYYVRQL  60
   61 RGSAPLINDP LLTQYINSLG MRLVSHANSV KTPFHFFLIN NDEINAFAFF GGNVVLHSAL 120
  121 FRYSDNESQL ASVMAHE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [138-487]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISHVTQRHLA RAMEDQQRSA PLTWVGALGS ILLAMASPQA GMAALTGTLA GTRQGMISFT  60
   61 QQNEQEADRI GIQVLQRSGF DPQAMPTFLE KLLDQARYSS RPPEILLTHP LPESRLADAR 120
  121 NRANQMRPMV VQSSEDFYLA KARTLGMYNS GRNQLTSDLL DEWAKGNVRQ QRAAQYGRAL 180
  181 QAMEANKYDE ARKTLQPLLA AEPGNAWYLD LATDIDLGQN KANEAINRLK NARDLRTNPV 240
  241 LQLNLANAYL QGGQPQEAAN ILNRYTFNNK DDSNGWDLLA QAEAALNNRD QELAARAEGY 300
  301 ALAGRLDQAI SLLSSASSQV KLGSLQQARY DARIDQLRQL QERFKPYTKM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.0
Match:	1w3bA
Description:	The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.38600536767442	bayes_pls_golite062009
protein binding	0.883964976625377	bayes_pls_golite062009
hydrolase activity	0.391317518372402	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: