YRC Public Data Repository - Protein Structure Prediction

Protein:	YFDZ_ECOLI
Organism:	Escherichia coli
Length:	412 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YFDZ_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|193069751, gi... - gi\|75235567\|ref\|ZP_00719758.1\| COG0436: Aspartate/tyrosine/aromatic aminotransferase [Escherichia co...	392.0	[0..1]	[412..1]
gi\|74312927, gi\|... - gi\|74312927\|ref\|YP_311346.1\| aminotransferase [Shigella sonnei Ss046], gi\|73856404\|gb\|AAZ89111.1\| pu...	392.0	[0..1]	[412..1]
gi\|194432938, gi... - gi\|83570023\|ref\|ZP_00921470.1\| COG0436: Aspartate/tyrosine/aromatic aminotransferase [Shigella dysen...	391.0	[0..1]	[412..1]
gi\|168780343, gi... - gi\|189001912\|gb\|EDU70898.1\| aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC4076... gi\|189372923, gi... - gi\|189372923\|gb\|EDU91339.1\| aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC869]... gi\|168800718, gi... - gi\|189377068\|gb\|EDU95484.1\| aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC508]... gi\|195938733 - gi\|195938733\|ref\|ZP_03084115.1\| aminotransferase [Escherichia coli O157:H7 str. EC4024] gi\|189355607, gi... - gi\|189355607\|gb\|EDU74026.1\| aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC4401... gi\|189366309, gi... - gi\|189366309\|gb\|EDU84725.1\| aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC4501... gi\|168770951, gi... - gi\|189360191\|gb\|EDU78610.1\| aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC4486... gi\|187771252, gi... - gi\|187771252\|gb\|EDU35096.1\| aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC4196... gi\|168748336, gi... - gi\|188017197\|gb\|EDU55319.1\| aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC4113... gi\|13362729, gi\|... - gi\|15832513\|ref\|NP_311286.1\| hypothetical protein ECs3259 [Escherichia coli O157:H7], gi\|13362729\|db... gi\|209764454, gi... - pir\|\|E85880 probable aminotransferase Z3644 [imported] - Escherichia coli (strain O157:H7, substrain... gi\|12516753, gi\|... - gi\|15802921\|ref\|NP_288949.1\| aminotransferase [Escherichia coli O157:H7 EDL933], gi\|12516753\|gb\|AAG5... gi\|254593741, gi... - gi\|254794341\|ref\|YP_003079178.1\| prediected aminotransferase, PLP-dependent [Escherichia coli O157:H... gi\|217327450, gi... - gi\|217327450\|ref\|ZP_03443533.1\| aminotransferase, classes I and II [Escherichia coli O157:H7 str. TW... gi\|13362729, gi\|... - gi\|15832513\|ref\|NP_311286.1\| aminotransferase [Escherichia coli O157:H7 str. Sakai], gi\|13362729\|dbj... gi\|208806924, gi... - gi\|208806924\|ref\|ZP_03249261.1\| aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC... gi\|208812373, gi... - gi\|208812373\|ref\|ZP_03253702.1\| aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC... gi\|208739597, gi... - gi\|208819474\|ref\|ZP_03259794.1\| aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC... gi\|209400401, gi... - gi\|209400401\|ref\|YP_002271865.1\| aminotransferase, classes I and II [Escherichia coli O157:H7 str. E...	391.0	[0..1]	[412..1]
gi\|187429810, gi... - gi\|75177846\|ref\|ZP_00697908.1\| COG0436: Aspartate/tyrosine/aromatic aminotransferase [Shigella boydi...	390.0	[0..1]	[412..1]
gi\|26109164, gi\|... - gi\|26248758\|ref\|NP_754798.1\| aminotransferase [Escherichia coli CFT073], gi\|26109164\|gb\|AAN81366.1\|A...	389.0	[0..1]	[412..1]
gi\|81246258, gi\|... - gi\|82544847\|ref\|YP_408794.1\| aminotransferase [Shigella boydii Sb227], gi\|81246258\|gb\|ABB66966.1\| pu...	389.0	[0..1]	[412..1]
gi\|82777783, gi\|... - gi\|82777783\|ref\|YP_404132.1\| aminotransferase [Shigella dysenteriae Sd197], gi\|81241931\|gb\|ABB62641....	388.0	[0..1]	[412..1]
gi\|30063785, gi\|... - gi\|30063785\|ref\|NP_837956.1\| aminotransferase [Shigella flexneri 2a str. 2457T], gi\|30042040\|gb\|AAP1... gi\|56480096, gi\|... - gi\|56480096\|ref\|NP_708249.2\| aminotransferase [Shigella flexneri 2a str. 301], gi\|56383647\|gb\|AAN439...	388.0	[0..1]	[412..1]
gi\|56412700, gi\|... - gi\|56412700\|ref\|YP_149775.1\| aminotransferase [Salmonella enterica subsp. enterica serovar Paratyphi... gi\|197093110, gi... - gi\|197361634\|ref\|YP_002141270.1\| aminotransferase [Salmonella enterica subsp. enterica serovar Parat...	380.0	[0..1]	[412..1]

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Predicted Domain #1

Region A:
Residues: [1-412]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADTRPERRF TRIDRLPPYV FNITAELKMA ARRRGEDIID FSMGNPDGAT PPHIVEKLCT  60
   61 VAQRPDTHGY STSRGIPRLR RAISRWYQDR YDVEIDPESE AIVTIGSKEG LAHLMLATLD 120
  121 HGDTVLVPNP SYPIHIYGAV IAGAQVRSVP LVEGVDFFNE LERAIRESYP KPKMMILGFP 180
  181 SNPTAQCVEL EFFEKVVALA KRYDVLVVHD LAYADIVYDG WKAPSIMQVP GARDVAVEFF 240
  241 TLSKSYNMAG WRIGFMVGNK TLVSALARIK SYHDYGTFTP LQVAAIAALE GDQQCVRDIA 300
  301 EQYKRRRDVL VKGLHEAGWM VEMPKASMYV WAKIPEPYAA MGSLEFAKKL LNEAKVCVSP 360
  361 GIGFGDYGDT HVRFALIENR DRIRQAIRGI KAMFRADGLL PASSKHIHEN AE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	104.0
Match:	1gd9A
Description:	Aromatic aminoacid aminotransferase, AroAT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
L-aspartate:2-oxoglutarate aminotransferase activity	5.51961002550688	bayes_pls_golite062009
4-aminobutyrate transaminase activity	2.50008459801306	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity	1.63055151623667	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	1.63055151623667	bayes_pls_golite062009
transferase activity	1.44093490824786	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
kynureninase activity	1.27354164393136	bayes_pls_golite062009
histidinol-phosphate transaminase activity	1.26617748508821	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances	0.942545094747784	bayes_pls_golite062009
hydrolase activity, acting on acid carbon-carbon bonds	0.845816961387768	bayes_pls_golite062009
5-aminolevulinate synthase activity	0.54326874956263	bayes_pls_golite062009
transferase activity, transferring acyl groups	0.319452731970428	bayes_pls_golite062009
vitamin B6 binding	0.16957228630576	bayes_pls_golite062009
pyridoxal phosphate binding	0.16957228630576	bayes_pls_golite062009
aromatic-amino-acid:2-oxoglutarate aminotransferase activity	0.0916183433120769	bayes_pls_golite062009
cystathionine beta-lyase activity	0.0833010353195099	bayes_pls_golite062009
nucleic acid binding	0.013097682076602	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: