YRC Public Data Repository - Protein Structure Prediction

Protein:	YFCG_ECOLI
Organism:	Escherichia coli
Length:	215 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YFCG_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|83748056, gi\|... - gi\|83748056\|ref\|ZP_00945085.1\| Glutathione S-transferase [Ralstonia solanacearum UW551], gi\|83725242... gi\|207742775, gi... - gi\|207742775\|ref\|YP_002259167.1\| glutathione-s-transferase protein [Ralstonia solanacearum IPO1609],...	222.0	[0..1]	[213..1]
gi\|45519430, gi\|... - gi\|73540704\|ref\|YP_295224.1\| glutathione S-transferase [Ralstonia eutropha JMP134], gi\|72118117\|gb\|A...	221.0	[0..1]	[205..1]
gi\|48770838, gi\|... - gi\|94309912\|ref\|YP_583122.1\| glutathione S-transferase-like protein [Ralstonia metallidurans CH34], ...	220.0	[0..1]	[205..1]
gi\|113525886, gi... - gi\|113867110\|ref\|YP_725599.1\| glutathione S-transferase [Ralstonia eutropha H16], gi\|113525886\|emb\|C...	219.0	[0..1]	[205..1]
gi\|17429039 - gi\|17429039\|emb\|CAD15723.1\| probable glutathione-s-transferase protein [Ralstonia solanacearum GMI10... gi\|17546740 - gi\|17546740\|ref\|NP_520142.1\| putative GST-related protein [Ralstonia solanacearum GMI1000]	219.0	[0..1]	[205..1]
gi\|116327436, gi... - gi\|116327436\|ref\|YP_797156.1\| glutathione transferase [Leptospira borgpetersenii serovar Hardjo-bovi...	218.0	[0..1]	[202..1]
gi\|67104621, gi\|... - gi\|67662036\|ref\|ZP_00459327.1\| Glutathione S-transferase, N-terminal:Glutathione S-transferase, C-te...	218.0	[0..1]	[205..21]
gi\|56313387, gi\|... - gi\|56477344\|ref\|YP_158933.1\| putative glutathione-S-transferase-related protein [Aromatoleum aromati...	218.0	[0..1]	[207..1]
gi\|24216055, gi\|... - gi\|24216055\|ref\|NP_713536.1\| glutathione S-transferase [Leptospira interrogans serovar Lai str. 5660...	217.0	[0..1]	[215..1]
gi\|116331951, gi... - gi\|116331951\|ref\|YP_801669.1\| glutathione transferase [Leptospira borgpetersenii serovar Hardjo-bovi...	217.0	[0..1]	[202..1]

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Predicted Domain #1

Region A:
Residues: [1-215]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIDLYFAPTP NGHKITLFLE EAELDYRLIK VDLGKGGQFR PEFLRISPNN KIPAIVDHSP  60
   61 ADGGEPLSLF ESGAILLYLA EKTGLFLSHE TRERAATLQW LFWQVGGLGP MLGQNHHFNH 120
  121 AAPQTIPYAI ERYQVETQRL YHVLNKRLEN SPWLGGENYS IADIACWPWV NAWTRQRIDL 180
  181 AMYPAVKNWH ERIRSRPATG QALLKAQLGD ERSDS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.0
Match:	1jzrA
Description:	Yeast prion protein ure2p, nitrogen regulation fragment
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
antioxidant activity	3.66884588063322	bayes_pls_golite062009
peroxidase activity	3.43831566988273	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	3.43831566988273	bayes_pls_golite062009
glutathione peroxidase activity	2.56524997297011	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.8187537496904	bayes_pls_golite062009
protein disulfide oxidoreductase activity	1.47769936616412	bayes_pls_golite062009
disulfide oxidoreductase activity	1.32811008894503	bayes_pls_golite062009
selenium binding	1.1082524159827	bayes_pls_golite062009
binding	0.704132579378598	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: