YRC Public Data Repository - Protein Structure Prediction

Protein:	ARNA_ECOLI, YFBG...
Organism:	Escherichia coli
Length:	660 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARNA_ECOLI, YFBG....

Description	E-value	Query Range	Subject Range
ARNA_ECOUT - Bifunctional polymyxin resistance protein ArnA OS=Escherichia coli (strain UTI89 / UPEC) GN=arnA PE=... ARNA_ECO45 - Bifunctional polymyxin resistance protein ArnA OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=ar... gi\|226901099, gi... - gi\|237704733\|ref\|ZP_04535214.1\| bifunctional polymyxin resistance protein aRNA [Escherichia sp. 3_2_... ARNA_ECOK1 - Bifunctional polymyxin resistance protein ArnA OS=Escherichia coli O1:K1 / APEC GN=arnA PE=3 SV=1	558.0	[0..1]	[660..1]
ARNA_PHOLL - Bifunctional polymyxin resistance protein ArnA OS=Photorhabdus luminescens subsp. laumondii (strain ... ARNA_PHOLL - Bifunctional polymyxin resistance protein arnA OS=Photorhabdus luminescens subsp. laumondii GN=arnA ...	558.0	[0..1]	[651..1]
ARNA_ECO8A - Bifunctional polymyxin resistance protein ArnA OS=Escherichia coli O8 (strain IAI1) GN=arnA PE=3 SV=... ARNA_ECO55 - Bifunctional polymyxin resistance protein ArnA OS=Escherichia coli (strain 55989 / EAEC) GN=arnA PE=... gi\|193062414, gi... - gi\|75259718\|ref\|ZP_00731020.1\| COG0451: Nucleoside-diphosphate-sugar epimerases [Escherichia coli E2... gi\|194414835, gi... - gi\|75211663\|ref\|ZP_00711742.1\| COG0451: Nucleoside-diphosphate-sugar epimerases [Escherichia coli B1... ARNA_ECO24 - Bifunctional polymyxin resistance protein ArnA OS=Escherichia coli O139:H28 (strain E24377A / ETEC) ... ARNA_ECOSE - Bifunctional polymyxin resistance protein ArnA OS=Escherichia coli (strain SE11) GN=arnA PE=3 SV=1	558.0	[0..1]	[660..1]
ARNA_ECOL6 - Bifunctional polymyxin resistance protein ArnA OS=Escherichia coli O6 GN=arnA PE=3 SV=1 ARNA_ECOL6 - Bifunctional polymyxin resistance protein ArnA OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 70092...	556.0	[0..1]	[660..1]
gi\|190909436, gi... - gi\|75243070\|ref\|ZP_00726776.1\| COG0451: Nucleoside-diphosphate-sugar epimerases [Escherichia coli F1... ARNA_ECOL5 - Bifunctional polymyxin resistance protein ArnA OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN...	556.0	[0..1]	[659..1]
ARNA_SHIBS - Bifunctional polymyxin resistance protein ArnA OS=Shigella boydii serotype 4 (strain Sb227) GN=arnA ...	555.0	[0..1]	[660..1]
gi\|191166526, gi... - gi\|75230359\|ref\|ZP_00716849.1\| COG0451: Nucleoside-diphosphate-sugar epimerases [Escherichia coli B7...	555.0	[0..1]	[660..1]
gi\|75238043, gi\|... - gi\|75238043\|ref\|ZP_00722048.1\| COG0451: Nucleoside-diphosphate-sugar epimerases [Escherichia coli E1...	554.0	[0..1]	[660..1]
ARNA_ECOHS - Bifunctional polymyxin resistance protein ArnA OS=Escherichia coli O9:H4 (strain HS) GN=arnA PE=3 SV...	554.0	[0..1]	[660..1]
gi\|189357598, gi... - gi\|189357598\|gb\|EDU76017.1\| UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyl... gi\|15802804, gi\|... - gi\|15802804\|ref\|NP_288831.1\| bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-ar... gi\|168761304, gi... - gi\|189368338\|gb\|EDU86754.1\| UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyl... gi\|168767883, gi... - gi\|189362879\|gb\|EDU81298.1\| UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyl... gi\|168773017, gi... - gi\|187771097\|gb\|EDU34941.1\| UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyl... gi\|188016114, gi... - gi\|188016114\|gb\|EDU54236.1\| UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyl... ARNA_ECO57 - Bifunctional polymyxin resistance protein ArnA OS=Escherichia coli O157:H7 GN=arnA PE=3 SV=1 gi\|217327888, gi... - gi\|217327888\|ref\|ZP_03443971.1\| UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose fo... gi\|254593550, gi... - gi\|254794150\|ref\|YP_003078987.1\| bifunctional UDP-L-Ara4N formyltransferase [Escherichia coli O157:H... gi\|15832397, gi\|... - gi\|15832397\|ref\|NP_311170.1\| bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-ar... gi\|208809714, gi... - gi\|208809714\|ref\|ZP_03252051.1\| UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose fo... gi\|208813824, gi... - gi\|208813824\|ref\|ZP_03255153.1\| UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose fo... gi\|208741590, gi... - gi\|208821467\|ref\|ZP_03261787.1\| UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose fo... ARNA_ECO5E - Bifunctional polymyxin resistance protein ArnA OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN... gi\|189002204, gi... - gi\|189002204\|gb\|EDU71190.1\| UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyl... gi\|168787165, gi... - gi\|189372920\|gb\|EDU91336.1\| UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyl... gi\|209765356, gi... - pir\|\|F85865 probable transformylase Z3513 [imported] - Escherichia coli (strain O157:H7, substrain ... gi\|189379016, gi... - gi\|189379016\|gb\|EDU97432.1\| UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyl... gi\|195935634 - gi\|195935634\|ref\|ZP_03081016.1\| bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L...	554.0	[0..1]	[660..1]

Back

Predicted Domain #1

Region A:
Residues: [1-660]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTVVFAYHD MGCLGIEALL AAGYEISAIF THTDNPGEKA FYGSVARLAA ERGIPVYAPD  60
   61 NVNHPLWVER IAQLSPDVIF SFYYRHLIYD EILQLAPAGA FNLHGSLLPK YRGRAPLNWV 120
  121 LVNGETETGV TLHRMVKRAD AGAIVAQLRI AIAPDDIAIT LHHKLCHAAR QLLEQTLPAI 180
  181 KHGNILEIAQ RENEATCFGR RTPDDSFLEW HKPASVLHNM VRAVADPWPG AFSYVGNQKF 240
  241 TVWSSRVHPH ASKAQPGSVI SVAPLLIACG DGALEIVTGQ AGDGITMQGS QLAQTLGLVQ 300
  301 GSRLNSQPAC TARRRTRVLI LGVNGFIGNH LTERLLREDH YEVYGLDIGS DAISRFLNHP 360
  361 HFHFVEGDIS IHSEWIEYHV KKCDVVLPLV AIATPIEYTR NPLRVFELDF EENLRIIRYC 420
  421 VKYRKRIIFP STSEVYGMCS DKYFDEDHSN LIVGPVNKPR WIYSVSKQLL DRVIWAYGEK 480
  481 EGLQFTLFRP FNWMGPRLDN LNAARIGSSR AITQLILNLV EGSPIKLIDG GKQKRCFTDI 540
  541 RDGIEALYRI IENAGNRCDG EIINIGNPEN EASIEELGEM LLASFEKHPL RHHFPPFAGF 600
  601 RVVESSSYYG KGYQDVEHRK PSIRNAHRCL DWEPKIDMQE TIDETLDFFL RTVDLTDKPS 660
  661

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	159.0
Match:	1z7eA
Description:	Crystal structure of full length ArnA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydroxymethyl-, formyl- and related transferase activity	5.69633962913959	bayes_pls_golite062009
methionyl-tRNA formyltransferase activity	5.65386414092027	bayes_pls_golite062009
methyltransferase activity	2.76628443233732	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	2.70337357342253	bayes_pls_golite062009
catalytic activity	2.53047786804923	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	2.44659532474253	bayes_pls_golite062009
ligase activity	1.96240394924455	bayes_pls_golite062009
oxidoreductase activity	1.95477050413	bayes_pls_golite062009
transferase activity	1.21569993951472	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	1.18415676807338	bayes_pls_golite062009
dTDP-4-dehydrorhamnose reductase activity	0.835820446605149	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.771153340292	bayes_pls_golite062009
DNA N-glycosylase activity	0.747108219360159	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.66554302844944	bayes_pls_golite062009
fatty acid synthase activity	0.561621495862231	bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds	0.432154504301609	bayes_pls_golite062009
phosphoribosylglycinamide formyltransferase activity	0.274274040236549	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: