YRC Public Data Repository - Protein Structure Prediction

Protein:	YEAG_ECOLI
Organism:	Escherichia coli
Length:	644 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YEAG_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|62127500, gi\|... - gi\|62179867\|ref\|YP_216284.1\| hypothetical protein SC1297 [Salmonella enterica subsp. enterica serova... gi\|224584208, gi... - gi\|224584208\|ref\|YP_002638006.1\| hypothetical protein SPC_2456 [Salmonella enterica subsp. enterica ...	635.0	[0..1]	[644..11]
gi\|194428508, gi... - gi\|75210260\|ref\|ZP_00710428.1\| COG2766: Putative Ser protein kinase [Escherichia coli B171], gi\|1944...	634.0	[0..1]	[644..1]
gi\|73855383, gi\|... - gi\|74311906\|ref\|YP_310325.1\| hypothetical protein SSON_1379 [Shigella sonnei Ss046], gi\|73855383\|gb\|...	633.0	[0..1]	[644..1]
gi\|204927511, gi... - gi\|204927511\|ref\|ZP_03218712.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica ser... gi\|207857214, gi... - gi\|207857214\|ref\|YP_002243865.1\| putative serine kinase [Salmonella enterica subsp. enterica serovar... gi\|198245623, gi... - gi\|198245623\|ref\|YP_002215850.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica se... gi\|199602229, gi... - gi\|200389784\|ref\|ZP_03216395.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica ser... gi\|197247484, gi... - gi\|197247484\|ref\|YP_002146754.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica se... gi\|197242819, gi... - gi\|197264564\|ref\|ZP_03164638.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica ser... gi\|194468848, gi... - gi\|194468848\|ref\|ZP_03074832.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica ser... gi\|194712239, gi... - gi\|194736737\|ref\|YP_002114302.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica se... gi\|194403963, gi... - gi\|194445300\|ref\|YP_002040542.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica se... gi\|194451442, gi... - gi\|194451442\|ref\|YP_002045291.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica se... gi\|238910898 - gi\|238910898\|ref\|ZP_04654735.1\| putative serine kinase [Salmonella enterica subsp. enterica serovar ... gi\|168264177, gi... - gi\|205347248\|gb\|EDZ33879.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica serovar... gi\|168463324, gi... - gi\|195634237\|gb\|EDX52589.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica serovar... gi\|16419801, gi\|... - gi\|16764636\|ref\|NP_460251.1\| putative serine protein kinase [Salmonella typhimurium LT2], gi\|1641980... gi\|197288271, gi... - gi\|197288271\|gb\|EDY27656.1\| PrkA AAA domain protein [Salmonella enterica subsp. enterica serovar Sch... gi\|205336740, gi... - gi\|205336740\|gb\|EDZ23504.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica serovar... gi\|167991904, gi... - gi\|205329684\|gb\|EDZ16448.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica serovar... gi\|205332604, gi... - gi\|205332604\|gb\|EDZ19368.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica serovar... lcl\|NC_016856.1_... - [gene=yeaG] [protein=putative serine protein kinase] [protein_id=YP_005237133.1] [location=complemen... gi\|161614316, gi... - gi\|161614316\|ref\|YP_001588281.1\| hypothetical protein SPAB_02062 [Salmonella enterica subsp. enteric... gi\|205322982, gi... - gi\|205322982\|gb\|EDZ10821.1\| serine protein kinase, PrkA [Salmonella enterica subsp. enterica serovar...	633.0	[0..1]	[644..1]
gi\|194421428, gi... - gi\|83584969\|ref\|ZP_00923624.1\| COG2766: Putative Ser protein kinase [Escherichia coli 101-1], gi\|194...	633.0	[0..1]	[644..1]
gi\|83569609, gi\|... - gi\|83569609\|ref\|ZP_00921060.1\| COG2766: Putative Ser protein kinase [Shigella dysenteriae 1012], gi\|...	632.0	[0..1]	[644..1]
gi\|213852769 - gi\|213852769\|ref\|ZP_03382301.1\| hypothetical protein SentesT_07856 [Salmonella enterica subsp. enter... gi\|214003039 - gi\|214003039\|ref\|ZP_03413774.1\| hypothetical protein Salmonellentericaenterica_23210 [Salmonella ent... gi\|29141632, gi\|... - gi\|29141632\|ref\|NP_804974.1\| hypothetical protein t1164 [Salmonella enterica subsp. enterica serovar... gi\|16760609 - gi\|16760609\|ref\|NP_456226.1\| hypothetical protein STY1831 [Salmonella enterica subsp. enterica serov... gi\|213161183 - gi\|213161183\|ref\|ZP_03346893.1\| hypothetical protein Salmoneentericaenterica_14540 [Salmonella enter... gi\|213613243 - gi\|213613243\|ref\|ZP_03371069.1\| hypothetical protein SentesTyp_12489 [Salmonella enterica subsp. ent... gi\|25287583, gi\|... - gi\|25287583\|pir\|\|AD0712 conserved hypothetical protein STY1831 [imported] - Salmonella enterica subs... gi\|213646212 - gi\|213646212\|ref\|ZP_03376265.1\| hypothetical protein SentesTy_01995 [Salmonella enterica subsp. ente...	631.0	[0..1]	[644..1]
gi\|194539923, gi... - gi\|75856409\|ref\|ZP_00764038.1\| COG2766: Putative Ser protein kinase [Vibrio sp. Ex25], gi\|254229010\|...	630.0	[0..1]	[644..20]
gi\|90410815, gi\|... - gi\|90410815\|ref\|ZP_01218830.1\| putative Ser protein kinase [Photobacterium profundum 3TCK], gi\|90328...	629.0	[0..1]	[644..1]
gi\|91225257, gi\|... - gi\|91225257\|ref\|ZP_01260425.1\| hypothetical protein V12G01_20858 [Vibrio alginolyticus 12G01], gi\|91...	628.0	[0..1]	[644..1]

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Predicted Domain #1

Region A:
Residues: [1-174]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIFDHYRQR YEAAKDEEFT LQEFLTTCRQ DRSAYANAAE RLLMAIGEPV MVDTAQEPRL  60
   61 SRLFSNRVIA RYPAFEEFYG MEDAIEQIVS YLKHAAQGLE EKKQILYLLG PVGGGKSSLA 120
  121 ERLKSLMQLV PIYVLSANGE RSPVNDHPFC LFNPQEDAQI LEKEYGIPRR YLGT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.0
Match:	1oz4A
Description:	VCP/p97
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.470983068319171	bayes_pls_golite062009
hydrolase activity	0.0582794297634999	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [175-481]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IMSPWAAKRL HEFGGDITKF RVVKVWPSIL QQIAIAKTEP GDENNQDISA LVGKVDIRKL  60
   61 EHYAQNDPDA YGYSGALCRA NQGIMEFVEM FKAPIKVLHP LLTATQEGNY NGTEGISALP 120
  121 FNGIILAHSN ESEWVTFRNN KNNEAFLDRV YIVKVPYCLR ISEEIKIYEK LLNHSELTHA 180
  181 PCAPGTLETL SRFSILSRLK EPENSSIYSK MRVYDGESLK DTDPKAKSYQ EYRDYAGVDE 240
  241 GMNGLSTRFA FKILSRVFNF DHVEVAANPV HLFYVLEQQI EREQFPQEQA ERYLEFLKGY 300
  301 LIPKYAE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.39794
Match:	1ojlA
Description:	Crystal structure of a sigma54-activator suggests the mechanism for the conformational switch necessary for sigma54 binding
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [482-644]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FIGKEIQTAY LESYSEYGQN IFDRYVTYAD FWIQDQEYRD PDTGQLFDRE SLNAELEKIE  60
   61 KPAGISNPKD FRNEIVNFVL RARANNSGRN PNWTSYEKLR TVIEKKMFSN TEELLPVISF 120
  121 NAKTSTDEQK KHDDFVDRMM EKGYTRKQVR LLCEWYLRVR KSS

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	67.102373
Match:	PF06798.3
Description:	No description for PF06798.3 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: