YRC Public Data Repository - Protein Structure Prediction

Protein:	YCIM_ECOLI
Organism:	Escherichia coli
Length:	389 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YCIM_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|71675440, gi\|... - gi\|71675440\|ref\|ZP_00673185.1\| TPR repeat:Sel1-like repeat [Trichodesmium erythraeum IMS101], gi\|716...	280.0	[0..8]	[371..1000]
gi\|91079875 - gi\|91079875\|ref\|XP_967579.1\| PREDICTED: similar to CG10392-PB, isoform B [Tribolium castaneum]	273.0	[0..6]	[356..265]
gi\|56967372, gi\|... - gi\|62821820\|ref\|NP_001017359.1\| O-linked N-acetylglucosamine transferase isoform 1 [Danio rerio], gi...	272.0	[0..6]	[356..128]
gi\|76659271 - gi\|76659271\|ref\|XP_884992.1\| PREDICTED: similar to O-linked GlcNAc transferase isoform 1 isoform 7 [...	269.0	[0..6]	[356..128]
gi\|72383071, gi\|... - gi\|72383071\|ref\|YP_292426.1\| TPR repeat-containing protein [Prochlorococcus marinus str. NATL2A], gi...	268.0	[0..6]	[357..107]
gi\|66793439, gi\|... - gi\|66793439\|ref\|NP_001019747.1\| UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase [Xe...	267.0	[0..6]	[356..118]

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Predicted Domain #1

Region A:
Residues: [1-389]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLELLFLLLP VAAAYGWYMG RRSAQQNKQD EANRLSRDYV AGVNFLLSNQ QDKAVDLFLD  60
   61 MLKEDTGTVE AHLTLGNLFR SRGEVDRAIR IHQTLMESAS LTYEQRLLAI QQLGRDYMAA 120
  121 GLYDRAEDMF NQLTDETDFR IGALQQLLQI YQATSEWQKA IDVAERLVKL GKDKQRVEIA 180
  181 HFYCELALQH MASDDLDRAM TLLKKGAAAD KNSARVSIMM GRVFMAKGEY AKAVESLQRV 240
  241 ISQDRELVSE TLEMLQTCYQ QLGKTAEWAE FLQRAVEENT GADAELMLAD IIEARDGSEA 300
  301 AQVYITRQLQ RHPTMRVFHK LMDYHLNEAE EGRAKESLMV LRDMVGEKVR SKPRYRCQKC 360
  361 GFTAYTLYWH CPSCRAWSTI KPIRGLDGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.045757
Match:	1w3bA
Description:	The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.439878494078852	bayes_pls_golite062009
protein binding	0.164436493568669	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: