YRC Public Data Repository - Protein Structure Prediction

Protein:	NAGK_ECOLI, YCFX...
Organism:	Escherichia coli
Length:	303 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAGK_ECOLI, YCFX....

Description	E-value	Query Range	Subject Range
NAGK_ECO24 - N-acetyl-D-glucosamine kinase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=nagK PE=3 SV=1	257.0	[0..1]	[303..1]
NAGK_ECOL5 - N-acetyl-D-glucosamine kinase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=nagK PE=3 SV=1 NAGK_ECOUT - N-acetyl-D-glucosamine kinase OS=Escherichia coli (strain UTI89 / UPEC) GN=nagK PE=3 SV=1 NAGK_ECOK1 - N-acetyl-D-glucosamine kinase OS=Escherichia coli O1:K1 / APEC GN=nagK PE=3 SV=1 NAGK_ECO45 - N-acetyl-D-glucosamine kinase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=nagK PE=3 SV=1 gi\|190906652, gi... - gi\|75239617\|ref\|ZP_00723584.1\| COG1940: Transcriptional regulator/sugar kinase [Escherichia coli F11... NAGK_ECO81 - N-acetyl-D-glucosamine kinase OS=Escherichia coli O81 (strain ED1a) GN=nagK PE=3 SV=1	257.0	[0..1]	[303..1]
gi\|254792502, gi... - gi\|254792502\|ref\|YP_003077339.1\| putative NAGC-like transcriptional regulator [Escherichia coli O157... gi\|168751331, gi... - gi\|188014653\|gb\|EDU52775.1\| N-acetylglucosamine kinase [Escherichia coli O157:H7 str. EC4113], gi\|16... NAGK_ECO57 - N-acetyl-D-glucosamine kinase OS=Escherichia coli O157:H7 GN=nagK PE=3 SV=1 gi\|25322560, gi\|... - pir\|\|E85675 probable NAGC-like transcription regulator ycfX [imported] - Escherichia coli (strain O1... gi\|12514669, gi\|... - gi\|15801236\|ref\|NP_287253.1\| N-acetyl-D-glucosamine kinase [Escherichia coli O157:H7 EDL933], gi\|125... gi\|217318680, gi... - gi\|217328253\|ref\|ZP_03444335.1\| N-acetylglucosamine kinase [Escherichia coli O157:H7 str. TW14588], ... gi\|208807822, gi... - gi\|208807822\|ref\|ZP_03250159.1\| N-acetylglucosamine kinase [Escherichia coli O157:H7 str. EC4206], g... gi\|208815520, gi... - gi\|208815520\|ref\|ZP_03256699.1\| N-acetylglucosamine kinase [Escherichia coli O157:H7 str. EC4045], g... gi\|208737799, gi... - gi\|208822314\|ref\|ZP_03262633.1\| N-acetylglucosamine kinase [Escherichia coli O157:H7 str. EC4042], g... NAGK_ECO5E - N-acetyl-D-glucosamine kinase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=nagK PE=3 SV=1 gi\|188999146, gi... - gi\|188999146\|gb\|EDU68132.1\| N-acetylglucosamine kinase [Escherichia coli O157:H7 str. EC4076], gi\|16... gi\|13360961, gi\|... - gi\|15830751\|ref\|NP_309524.1\| N-acetyl-D-glucosamine kinase [Escherichia coli O157:H7 str. Sakai], gi... gi\|189370373, gi... - gi\|189370373\|gb\|EDU88789.1\| N-acetylglucosamine kinase [Escherichia coli O157:H7 str. EC869], gi\|168... gi\|189377266, gi... - gi\|189377266\|gb\|EDU95682.1\| N-acetylglucosamine kinase [Escherichia coli O157:H7 str. EC508], gi\|168... gi\|195938878 - gi\|195938878\|ref\|ZP_03084260.1\| N-acetyl-D-glucosamine kinase [Escherichia coli O157:H7 str. EC4024] gi\|168757834, gi... - gi\|189355225\|gb\|EDU73644.1\| N-acetylglucosamine kinase [Escherichia coli O157:H7 str. EC4401], gi\|16... gi\|168764589, gi... - gi\|189365421\|gb\|EDU83837.1\| N-acetylglucosamine kinase [Escherichia coli O157:H7 str. EC4501], gi\|16... gi\|189359849, gi... - gi\|189359849\|gb\|EDU78268.1\| N-acetylglucosamine kinase [Escherichia coli O157:H7 str. EC4486], gi\|16... gi\|168776787, gi... - gi\|187767892\|gb\|EDU31736.1\| N-acetylglucosamine kinase [Escherichia coli O157:H7 str. EC4196], gi\|16...	257.0	[0..1]	[303..1]
NAGK_ECOL6 - N-acetyl-D-glucosamine kinase OS=Escherichia coli O6 GN=nagK PE=3 SV=1 NAGK_ECOL6 - N-acetyl-D-glucosamine kinase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=nagK...	256.0	[0..1]	[303..1]
gi\|124529866, gi... - gi\|124529866\|ref\|ZP_01700710.1\| ROK family protein [Escherichia coli B], gi\|124499574\|gb\|EAY47060.1... NAGK_ECOHS - N-acetyl-D-glucosamine kinase OS=Escherichia coli O9:H4 (strain HS) GN=nagK PE=3 SV=1 NAGK_ECOLC - N-acetyl-D-glucosamine kinase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=nagK PE=...	256.0	[0..1]	[303..1]
gi\|194421360, gi... - gi\|83584886\|ref\|ZP_00923544.1\| COG1940: Transcriptional regulator/sugar kinase [Escherichia coli 101...	256.0	[0..1]	[303..1]
NAGK_SHIBS - N-acetyl-D-glucosamine kinase OS=Shigella boydii serotype 4 (strain Sb227) GN=nagK PE=3 SV=1	253.0	[0..1]	[303..1]
NAGK_HAES1 - N-acetyl-D-glucosamine kinase OS=Haemophilus somnus (strain 129Pt) GN=nagK PE=3 SV=1	251.0	[0..1]	[302..1]
gi\|170717772, gi... - gi\|32030010\|ref\|ZP_00132938.1\| COG1940: Transcriptional regulator/sugar kinase [Haemophilus somnus 2...	250.0	[0..1]	[302..1]

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Predicted Domain #1

Region A:
Residues: [1-303]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYYGFDIGGT KIALGVFDSG RQLQWEKRVP TPRDSYDAFL DAVCELVAEA DQRFGCKGSV  60
   61 GIGIPGMPET EDGTLYAANV PAASGKPLRA DLSARLDRDV RLDNDANCFA LSEAWDDEFT 120
  121 QYPLVMGLIL GTGVGGGLIF NGKPITGKSY ITGEFGHMRL PVDALTMMGL DFPLRRCGCG 180
  181 QHGCIENYLS GRGFAWLYQH YYHQPLQAPE IIALYDQGDE QARAHVERYL DLLAVCLGNI 240
  241 LTIVDPDLVV IGGGLSNFPA ITTQLADRLP RHLLPVARVP RIERARHGDA GGMRGAAFLH 300
  301 LTD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.0
Match:	2ap1A
Description:	Crystal structure of the putative regulatory protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbohydrate kinase activity	0.7849166795124	bayes_pls_golite062009
catalytic activity	0.666924658593345	bayes_pls_golite062009
hexokinase activity	0.32024736915472	bayes_pls_golite062009
binding	0.107823909095522	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: