YRC Public Data Repository - Protein Structure Prediction

Protein:	YCFH_ECOLI
Organism:	Escherichia coli
Length:	265 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YCFH_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|52078534, gi\|... - gi\|52783896\|ref\|YP_089725.1\| YabD [Bacillus licheniformis ATCC 14580], gi\|52346398\|gb\|AAU39032.1\| Ya...	289.0	[0..2]	[257..1]
gi\|89084133, gi\|... - gi\|89101165\|ref\|ZP_01173998.1\| YabD [Bacillus sp. NRRL B-14911], gi\|89084133\|gb\|EAR63301.1\| YabD [Ba...	286.0	[0..2]	[257..1]
gi\|91201025 - gi\|91201025\|emb\|CAJ74083.1\| conserved hypothetical protein [Candidatus Kuenenia stuttgartiensis]	286.0	[0..1]	[261..15]
gi\|170707566, gi... - gi\|170707566\|ref\|ZP_02898019.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0389], gi\|1... gi\|177655347, gi... - gi\|177655347\|ref\|ZP_02936876.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0174], gi\|1... gi\|190568989, gi... - gi\|190568989\|ref\|ZP_03021890.1\| deoxyribonuclease, TatD family [Bacillus anthracis Tsiankovskii-I], ... gi\|196036356, gi... - gi\|196036356\|ref\|ZP_03103753.1\| deoxyribonuclease, TatD family [Bacillus cereus W], gi\|195990986\|gb\|... gi\|196027406, gi... - gi\|196041786\|ref\|ZP_03109076.1\| deoxyribonuclease, TatD family [Bacillus cereus NVH0597-99], gi\|1960... gi\|218535153, gi... - gi\|218901240\|ref\|YP_002449074.1\| deoxyribonuclease, TatD family [Bacillus cereus AH820], gi\|21853515... gi\|164711717, gi... - gi\|165872589\|ref\|ZP_02217221.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0488], gi\|1... gi\|167635090, gi... - gi\|167635090\|ref\|ZP_02393407.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0442], gi\|1... gi\|167510519, gi... - gi\|167641534\|ref\|ZP_02399782.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0193], gi\|1... gi\|170667141, gi... - gi\|170688917\|ref\|ZP_02880119.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0465], gi\|1... gi\|254762418 - gi\|254762418\|ref\|ZP_05214260.1\| deoxyribonuclease, TatD family protein [Bacillus anthracis str. Aust... gi\|254756362 - gi\|254756362\|ref\|ZP_05208391.1\| deoxyribonuclease, TatD family protein [Bacillus anthracis str. Voll... gi\|254744657 - gi\|254744657\|ref\|ZP_05202336.1\| deoxyribonuclease, TatD family protein [Bacillus anthracis str. Krug... gi\|254733575 - gi\|254733575\|ref\|ZP_05191296.1\| deoxyribonuclease, TatD family protein [Bacillus anthracis str. West... gi\|254682334 - gi\|254682334\|ref\|ZP_05146195.1\| deoxyribonuclease, TatD family protein [Bacillus anthracis str. CNEV... gi\|229604431, gi... - gi\|229604431\|ref\|YP_002864690.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. A0248], gi\|... gi\|229119702, gi... - gi\|229119702\|ref\|ZP_04248964.1\| Uncharacterized deoxyribonuclease yabD [Bacillus cereus 95/8201], gi... gi\|49477127, gi\|... - gi\|49477127\|ref\|YP_034393.1\| TatD related DNase [Bacillus thuringiensis serovar konkukian str. 97-27... gi\|229089171, gi... - gi\|229089171\|ref\|ZP_04220453.1\| Uncharacterized deoxyribonuclease yabD [Bacillus cereus Rock3-42], g... gi\|228815803, gi... - gi\|228943846\|ref\|ZP_04106232.1\| Uncharacterized deoxyribonuclease yabD [Bacillus thuringiensis serov... gi\|228828094, gi... - gi\|228931542\|ref\|ZP_04094449.1\| Uncharacterized deoxyribonuclease yabD [Bacillus thuringiensis serov... gi\|228912779, gi... - gi\|228912779\|ref\|ZP_04076427.1\| Uncharacterized deoxyribonuclease yabD [Bacillus thuringiensis serov... gi\|227002938, gi... - gi\|227812712\|ref\|YP_002812721.1\| deoxyribonuclease, TatD family [Bacillus anthracis str. CDC 684], g... gi\|49177000, gi\|... - gi\|49183073\|ref\|YP_026325.1\| TatD family deoxyribonuclease [Bacillus anthracis str. Sterne], gi\|4917... gi\|47500440, gi\|... - gi\|47525292\|ref\|YP_016641.1\| TatD family deoxyribonuclease [Bacillus anthracis str. 'Ames Ancestor']... gi\|30253550, gi\|... - gi\|30260229\|ref\|NP_842606.1\| TatD family deoxyribonuclease [Bacillus anthracis str. Ames], gi\|302535... gi\|21398002, gi\|... - gi\|65317499\|ref\|ZP_00390458.1\| COG0084: Mg-dependent DNase [Bacillus anthracis str. A2012], ref\|NP_6...	286.0	[0..2]	[257..1]
YABD_BACSU - Uncharacterized metal-dependent hydrolase YabD OS=Bacillus subtilis (strain 168) GN=yabD PE=3 SV=1 YABD_BACSU - Uncharacterized deoxyribonuclease YabD OS=Bacillus subtilis GN=yabD PE=3 SV=1 gi\|221312170 - gi\|221312170\|ref\|ZP_03593975.1\| hypothetical protein BsubsN3_00195 [Bacillus subtilis subsp. subtili... gi\|221321366 - gi\|221321366\|ref\|ZP_03602660.1\| hypothetical protein BsubsS_00195 [Bacillus subtilis subsp. subtilis... gi\|221317103 - gi\|221317103\|ref\|ZP_03598397.1\| hypothetical protein BsubsJ_00195 [Bacillus subtilis subsp. subtilis...	285.0	[0..2]	[257..1]
gi\|95133324, gi\|... - gi\|95930672\|ref\|ZP_01313406.1\| TatD-related deoxyribonuclease [Desulfuromonas acetoxidans DSM 684], ...	284.0	[0..3]	[263..6]
gi\|217066631, gi... - gi\|217957615\|ref\|YP_002336157.1\| deoxyribonuclease, TatD family [Bacillus cereus AH187], gi\|21706663... gi\|229136886, gi... - gi\|229136886\|ref\|ZP_04265514.1\| Uncharacterized deoxyribonuclease yabD [Bacillus cereus BDRD-ST26], ... gi\|222093809, gi... - gi\|222093809\|ref\|YP_002527858.1\| TatD related DNase [Bacillus cereus Q1], gi\|221237856\|gb\|ACM10566.1... gi\|228983295, gi... - gi\|228983295\|ref\|ZP_04143509.1\| Uncharacterized deoxyribonuclease yabD [Bacillus thuringiensis serov... gi\|206743852, gi... - gi\|206977946\|ref\|ZP_03238833.1\| deoxyribonuclease, TatD family [Bacillus cereus H3081.97], gi\|206743... gi\|228629622, gi... - gi\|229153818\|ref\|ZP_04281949.1\| Uncharacterized deoxyribonuclease yabD [Bacillus cereus ATCC 4342], ... gi\|47569888, gi\|... - gi\|47569888\|ref\|ZP_00240555.1\| sec-independent secretion protein tatD [Bacillus cereus G9241], gi\|47...	284.0	[0..2]	[257..1]
gi\|89207208, gi\|... - gi\|89207208\|ref\|ZP_01185754.1\| TatD-related deoxyribonuclease [Bacillus weihenstephanensis KBAB4], g... gi\|229131047, gi... - gi\|229131047\|ref\|ZP_04259960.1\| Uncharacterized deoxyribonuclease yabD [Bacillus cereus BDRD-ST196],... gi\|228751693, gi... - gi\|229009549\|ref\|ZP_04166776.1\| Uncharacterized deoxyribonuclease yabD [Bacillus mycoides DSM 2048],... gi\|229165028, gi... - gi\|229165028\|ref\|ZP_04292824.1\| Uncharacterized deoxyribonuclease yabD [Bacillus cereus AH621], gi\|2...	283.0	[0..2]	[257..1]
gi\|42735033, gi\|... - gi\|42779118\|ref\|NP_976365.1\| TatD family deoxyribonuclease [Bacillus cereus ATCC 10987], gi\|42735033...	283.0	[0..2]	[257..1]
gi\|52145176, gi\|... - gi\|52145176\|ref\|YP_081652.1\| TatD related DNase [Bacillus cereus E33L], gi\|51978645\|gb\|AAU20195.1\| T...	283.0	[0..2]	[257..1]

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Predicted Domain #1

Region A:
Residues: [1-265]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLVDSHCHL DGLDYESLHK DVDDVLAKAA ARDVKFCLAV ATTLPGYLHM RDLVGERDNV  60
   61 VFSCGVHPLN QNDPYDVEDL RRLAAEEGVV ALGETGLDYY YTPETKVRQQ ESFIHHIQIG 120
  121 RELNKPVIVH TRDARADTLA ILREEKVTDC GGVLHCFTED RETAGKLLDL GFYISFSGIV 180
  181 TFRNAEQLRD AARYVPLDRL LVETDSPYLA PVPHRGKENQ PAMVRDVAEY MAVLKGVAVE 240
  241 ELAQVTTDNF ARLFHIDASR LQSIR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	75.69897
Match:	1yixA
Description:	Crystal structure of YCFH, TATD homolog from Escherichia coli K12, at 1.9 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	3.06979421893431	bayes_pls_golite062009
catalytic activity	1.70199291046899	bayes_pls_golite062009
binding	0.420164638111423	bayes_pls_golite062009
deoxyribonuclease activity	0.375250302403787	bayes_pls_golite062009
protein binding	0.0854348074331311	bayes_pls_golite062009
peptidase activity	0.00898222301952797	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: